Compare and book 4 Star hotels in Murrells Inlet, South Carolina

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Murrells Inlet 4 Star Hotels

Our top choices for Murrells Inlet 4-star hotels

Terrace/patio
Willow Lodge

Willow Lodge

Willow Lodge
4.0 star property
Murrells Inlet
9.6 out of 10, Exceptional, (803)
"Awesome place. Would not hesitate to stay there again. "
United States
Karen
The price is 5.766.489 ₫
6.729.677 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Willow Lodge
Condo, 1 Bedroom | Exterior
0406 Waters Edge Resort 1 Bedroom Condo by RedAwning

0406 Waters Edge Resort 1 Bedroom Condo by RedAwning

0406 Waters Edge Resort 1 Bedroom Condo by RedAwning
4.0 star property
Murrells Inlet
0406 Waters Edge Resort 1 Bedroom Condo by RedAwning
Room | Terrace/patio
The Sanctuary

The Sanctuary

The Sanctuary
4.0 star property
Murrells Inlet
The Sanctuary
4 bedrooms, free WiFi, bed sheets
On Point

On Point

On Point
4.0 star property
Murrells Inlet
On Point
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Murrells Inlet

Stroll the scenic Marsh Walk at sunset when local musicians perform and seafood restaurants serve the day's fresh catch. Rent a kayak to explore salt marshes where dolphins surface, or book a fishing charter to reel in flounder and red drum.

See all hotels in Murrells Inlet
Murrells Inlet showing a small town or village, wetlands and a sunset

Top Murrells Inlet Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Murrells Inlet?
Expedia can help you quickly track down the perfect 4-star hotel for your holiday in Murrells Inlet. Use our handy filter tool to fine-tune your search by things like amenities, budget and property star rating and get access to awesome deals in a few clicks.

  • Search for the lowest price from 6.729.677 ₫

What's the difference between 5-star and 4-star hotels in Murrells Inlet?
Treat yourself to luxury during your Murrells Inlet getaway by checking in to a 4-star hotel. As well as featuring upmarket accommodation, these retreats are typically filled with amenities such as bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your stay an even more lavish and memorable one. 24-hour concierge assistance, luxurious spas and gourmet dining are just the start of the first-rate conveniences and services you'll likely get access to.
Does Murrells Inlet have any 4-star all-inclusive resorts?
Finding your dream hotel in Murrells Inlet is as easy as entering your dates and destination, and clicking on our "All inclusive" filter. Stay and play where everything is already taken care of like your meals, accommodation, entertainment and activities, or opt for a standard 4-star resort in or around this sought-after destination.