St. Peter's Square with the obelisk, colonnades, and Bernini's sculpture of a man with a scythe.

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Check availability on Vatican City 4 Star Hotels

Tonight
20 Oct - 21 Oct
Tomorrow
21 Oct - 22 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Vatican City 4-star hotels

An outdoor cafe with tables and chairs, a view of the street, and buildings in the background.
A hotel reception area with a wooden reception desk, a glass door entrance, and a view of the street outside.
A modern dining area with patterned chairs, tables, and potted plants.
A modern interior with a white armchair, wooden panel wall, and a glass door leading to an outdoor balcony.

1. Hotel Delle Nazioni

Hotel Delle Nazioni
Rome City Centre
Canada
Asha
5.260.147 ₫
6.222.523 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hotel Delle Nazioni
A rooftop restaurant with tables set for dining, overlooking a cityscape.
A rooftop restaurant with white wicker furniture, tables set with white tablecloths, and red flowers. A view of a cityscape with historic buildings is visible in the background.
A marble-floored lobby with a red carpeted staircase, a reception desk, and a red chair.
A lobby with a fireplace, red and blue chairs, marble walls, and wall sconces.

2. Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo
Rome City Centre
United States
Luis
4.784.751 ₫
5.698.779 ₫ total
includes taxes & fees
20 Nov - 21 Nov
Bettoja Hotel Mediterraneo
A dining area with round tables and purple chairs, large windows with a city view, and a red sofa.
A bar with various drinks and bottles, a fruit bowl, and a cityscape with mountains in the background.
A modern hotel room with a large bed, a desk, and a chair.
A terrace with a table set for dining, overlooking a cityscape with historic buildings and a prominent archway.

3. Marcella Royal Hotel - Rooftop Garden

Marcella Royal Hotel - Rooftop Garden
Rome City Centre
United Kingdom
Kelly Ann
4.117.959 ₫
4.965.308 ₫ total
includes taxes & fees
16 Nov - 17 Nov
Marcella Royal Hotel - Rooftop Garden
A courtyard with outdoor seating, a statue, and surrounding buildings.
A hotel room with a large bed, a sitting area with a chair and a small table, a desk, and a chandelier.
A room with green patterned sofas, a coffee table with magazines, a fireplace, and a television mounted on the wall.
A spacious lobby with a central round table, multiple seating arrangements, and red curtains.

4. Hotel Quirinale

Hotel Quirinale
Rome City Centre
United States
Kayleigh
4.540.208 ₫
5.429.898 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hotel Quirinale
An outdoor patio with wooden flooring, white and black chairs, and large umbrellas.
A modern hotel building with a sign for 'HOTELS' and 'La Fatalignorante Rooftop Restaurant'.
A hotel room with three beds, a television, a desk, and a window with curtains.
A buffet area with various food items and a clock on the wall.

5. iQ Hotel Roma

iQ Hotel Roma
Rome City Centre
United States
Ronald
6.308.924 ₫
7.375.369 ₫ total
includes taxes & fees
15 Nov - 16 Nov
iQ Hotel Roma
A historic building with multiple stories, ornate architectural details, and a street in front with cars and illuminated storefronts.
A hot tub with steps and metal railings, surrounded by mosaic-tiled walls and a stone-like textured wall.
A spacious lobby with a glass table, a sofa, and a vase with flowers.
A professional kitchen with stainless steel appliances, a large pot on the counter, and chefs in white uniforms.

6. Hotel Artemide

Hotel Artemide
Rome City Centre
United States
Lisa
6.704.881 ₫
7.810.922 ₫ total
includes taxes & fees
18 Nov - 19 Nov
Hotel Artemide
An outdoor seating area with wicker chairs and tables, a 'VIVANI' sign, and greenery.
An outdoor dining area with wicker chairs, a wooden table, and string lights.
A modern bedroom with a large bed, a nightstand, a desk, and a large window.
A narrow street with historic buildings, including a building with "DI VIRO STET CALO" inscribed on it.

7. Hotel 55 Fifty five

Hotel 55 Fifty five
Rome City Centre
United States
JESUS ANTONIO
3.308.418 ₫
4.075.621 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hotel 55 Fifty five
A narrow alleyway with a shop on the left and a door on the right.
A narrow alleyway with buildings on either side, featuring balconies and windows.
Living area
A rooftop terrace with wicker furniture, potted plants, and a view of surrounding buildings.

8. Condotti Boutique Hotel

Condotti Boutique Hotel
Rome City Centre
United States
Diana
4.333.465 ₫
5.202.364 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Condotti Boutique Hotel
A balcony with a table set with two glasses of red drink, a bowl of nuts, and a vase of flowers.
An arched doorway leading to a street with pedestrians.
A bedroom with a large bed, a brick wall, a window with a view of buildings, and a vase with flowers.
A hotel entrance with a reception desk, a potted plant, and a stone fountain.

9. Argentina Residenza Style Hotel

Argentina Residenza Style Hotel
Rome City Centre
United States
Nathaniel
5.110.734 ₫
6.057.360 ₫ total
includes taxes & fees
18 Nov - 19 Nov
Argentina Residenza Style Hotel
A balcony with a table set for two, overlooking a cityscape with domed buildings.
A hotel entrance with numbered doors, a revolving door, and two potted plants.
A bar area with a bartender, bar counter, and seating arrangement.
A hotel room with a bed, a desk with a lamp, a chair, and a view of the outside.

10. UNA Hotels Decò Roma

UNA Hotels Decò Roma
Rome City Centre
United States
Anthony
3.425.032 ₫
4.203.089 ₫ total
includes taxes & fees
8 Nov - 9 Nov
UNA Hotels Decò Roma
A rooftop dining area with a table set for two, surrounded by potted plants and overlooking historic buildings.
A modern restaurant interior with hexagonal ceiling panels, black tables, and chairs.
A modern indoor pool area with a tiled floor, a seating area with cushioned benches, and a wall with a geometric pattern.
A modern hotel room with a large bed, a nightstand, a wall-mounted mirror, and a ceiling light fixture.

11. The Hive Hotel

The Hive Hotel
Rome City Centre
United States
Kristi
4.103.176 ₫
4.949.046 ₫ total
includes taxes & fees
11 Nov - 12 Nov
The Hive Hotel
An outdoor dining area with tables set for breakfast, overlooking a cityscape with domed buildings and a tower.
A buffet with various food items, including breads, pastries, and fruits.
A breakfast tray with croissants, eggs, bacon, and fruit on a hotel room table.
The entrance to Hotel Gioberti with a modern design, featuring a large illuminated sign, stone walls, and a well-lit interior visible through the glass doors.

12. Gioberti Hotel

Gioberti Hotel
Rome City Centre
United States
paulina
4.601.584 ₫
5.498.163 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Gioberti Hotel
A multi-story building with a corner entrance, featuring a boutique store named 'nina' on the ground floor.
A buffet setup with various food items and a coffee machine.
A room with a red chair, a sliding glass door leading to a balcony with potted plants and a view of buildings.
A reception desk with two staff members, a chandelier, and a clock on the wall.

13. Augusta Lucilla Palace

Augusta Lucilla Palace
Rome City Centre
United States
Jose
2.878.347 ₫
3.601.735 ₫ total
includes taxes & fees
16 Nov - 17 Nov
Augusta Lucilla Palace
A rooftop bar with a panoramic city view, featuring a curved bar and seating area.
A multi-story building with classical architecture, featuring ornate balconies and multiple windows.
A couple dining at a table with a cityscape view, including a prominent dome structure.
A hotel room with a view of a building through a window, a wooden bench, and a floor lamp.

14. Best Western Plus Hotel Universo

Best Western Plus Hotel Universo
Rome City Centre
United States
Van
5.015.462 ₫
5.952.561 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Best Western Plus Hotel Universo
An outdoor seating area with tables and chairs, a red table, and a lamp post.
A modern cafe with a checkered floor, a central serving counter with fresh produce, and seating areas with a view of the city.
A modern bedroom with a large window, a bed, and a TV mounted on the wall.
A person preparing a drink at a bar with a modern interior, including pendant lighting and a view of the city through large windows.

15. citizenM Rome Isola Tiberina

citizenM Rome Isola Tiberina
Rome City Centre
United States
Coraima
4.962.668 ₫
5.894.488 ₫ total
includes taxes & fees
15 Nov - 16 Nov
citizenM Rome Isola Tiberina
An outdoor dining area with wicker chairs and a round table set for two, overlooking a historic building with domed architecture.
A person in a white robe standing by a window with a view of a classical building.
The exterior of The Majestic Hotel with a classic entrance, a metal awning, and a street view through the windows.
A modern interior with a fireplace, shelves with decorative items, and two upholstered chairs.

16. The Major

The Major
Rome City Centre
United States
Matthew
5.301.799 ₫
6.268.341 ₫ total
includes taxes & fees
27 Oct - 28 Oct
The Major
A balcony with wicker furniture, a red sofa, and a table with a glass of wine.
A hotel lobby with a chandelier, a reception desk, and a large painting on the wall.
A hotel room with a large bed, bedside tables, a desk with a chair, and two paintings on the walls.
A hotel with a red awning, outdoor seating, and potted plants.

17. Hotel Homs

Hotel Homs
Rome City Centre
United States
Scott
3.207.256 ₫
3.963.535 ₫ total
includes taxes & fees
18 Nov - 19 Nov
Hotel Homs
A spacious lobby with a central glass-top table, flanked by sofas and chairs, and a decorative floral arrangement.
A hotel entrance with two arched doorways, each adorned with a bow and festive garlands.
A large Christmas tree in a hotel lobby with a geometric tile floor and classical architecture.
A bartender at a bar with shelves of liquor bottles in the background.

18. River Palace Hotel

River Palace Hotel
Municipio I
Canada
Robert
4.646.811 ₫
5.547.045 ₫ total
includes taxes & fees
16 Nov - 17 Nov
River Palace Hotel
A hotel lobby with three arched doorways, each labeled with a room number and a sign indicating the hotel name.
A multi-story hotel with a classic architectural style, featuring a central entrance with arched windows and a prominent sign.
A hotel lobby with a reception desk, a seating area with a sofa and ottoman, and two potted plants.
A modern interior with a staircase, seating area, and bar.

19. The Republic Hotel

The Republic Hotel
Rome City Centre
United States
Michael
4.077.416 ₫
4.921.519 ₫ total
includes taxes & fees
8 Nov - 9 Nov
The Republic Hotel
A balcony with a sofa, chairs, a table, and a potted plant.
A spacious balcony with a sofa, chairs, and a dining table. A television is mounted on the wall, and a potted plant is on the table.
A bar area with a marble counter, red chairs, and a patterned carpet.
A hotel room with a large bed, a desk with a chair, a television, and a mirror.

20. Hotel Nazionale

Hotel Nazionale
Rome City Centre
United States
Richard
4.959.384 ₫
5.890.876 ₫ total
includes taxes & fees
16 Nov - 17 Nov
Hotel Nazionale
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Vatican City.
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

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15.938.612 ₫
18.113.211 ₫ total
3 Nov - 4 Nov
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
InterContinental Rome Ambasciatori Palace by IHG

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11.927.231 ₫
13.701.770 ₫ total
15 Nov - 16 Nov
includes taxes & fees
InterContinental Rome Ambasciatori Palace by IHG
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

Via Vittorio Veneto 72 Rome RM
10.996.325 ₫
12.677.774 ₫ total
9 Nov - 10 Nov
includes taxes & fees
Baglioni Hotel Regina - The Leading Hotels of the World
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Vatican City

Marvel at Michelangelo's masterpiece ceiling in the Sistine Chapel before climbing St. Peter's Basilica dome for panoramic views. Reserve tickets for the Vatican Museums well in advance to explore one of the world's greatest art collections without the longest lines.

See all hotels in Vatican City
St. Peter's Square with the obelisk, colonnades, and Bernini's sculpture of a man with a scythe.

Top Vatican City Hotel Reviews

Aria Palace by OMNIA Hotels

Aria Palace by OMNIA Hotels

8/10 Good
"Breakfast excellent, staff excellent, air conditionné ok, gros dégât d’eau dans notre chambre et pas de réglage de la climatisation."
Pierre 1-night trip
Posted 6 hours ago
Aria Palace by OMNIA Hotels
The Major

The Major

10/10 Excellent
"convenient to Tremini and easy to sights and restaurants. staff is nice, great rooftop bar. Very clean all over. Would stay again."
Jeffrey 1-night trip
Posted 9 hours ago
The Major
Best Western Plus Hotel Universo

Best Western Plus Hotel Universo

10/10 Excellent
"Chambre très confortable, propre et spacieuse. Personnel très sympathique et courtois. Je recommande vivement cet hôtel qui est très près de la gare (train, métro et autobus) et près des attractions à visiter (à pied ou en métro)."
Natalie 17-night trip
Posted 2 days ago
Best Western Plus Hotel Universo
Hotel Artemide

Hotel Artemide

10/10 Excellent
"Everyone was very nice and professional. The breakfast was amazing. Nice location in the city."
MICHAEL 3-night trip
Posted 3 days ago
Hotel Artemide
iQ Hotel Roma

iQ Hotel Roma

8/10 Good
"Clean room, good staff, closed to Roma Termi, only one thing confused me - VERY SMALL ROOMS…."
Tatiana 1-night trip
Posted 6 days ago
iQ Hotel Roma
The Guardian Hotel

The Guardian Hotel

8/10 Good
"Clean room"
Vicente 2-night trip
Posted 7 days ago
The Guardian Hotel

Frequently asked questions

What are the best 4-star hotels in Vatican City?
Relax in 4-star hotel comfort at Columbus. Ranked highly by many Expedia guests, it features room service and a garden. Also have a look at Elle Boutique Hotel. Concierge services and a garden help make this stay another sought-after choice in Vatican City.
How much does it cost to stay in a 4-star hotel in Vatican City?
With Expedia's handy filter tool, bagging a terrific deal on a 4-star hotel in Vatican City just got easier. Start by entering your chosen travel dates and length of your getaway. Then list the results by price and pick a property that best fits your style and budget.
  • Search for the lowest price from 12.677.774 ₫
What's the difference between 5-star and 4-star hotels in Vatican City?
If you decide to book a stay at a 4-star hotel in Vatican City, you'll typically find plenty of amenities to keep you relaxed, such as a pool, gym and restaurant. You can look forward to excellent service and upmarket surroundings. Opt for a 5-star hotel and you'll get a few extra bells and whistles — think concierge assistance, on-site spas and indulgent turndown services. You're likely to get additional amenities and first-class services at a 5-star stay, though both are fabulous options for luxury travellers.