
Downtown West Holidays
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Where to stay in Downtown West
Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West

Downtown St. Louis
4 out of top 10 points of interest in this area
4.5/5(18 area reviews)
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Top hotels in Downtown West

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 3.773.111 ₫ per night from 1 Feb to 2 Feb
3.773.111 ₫
4.543.192 ₫ total
1 Feb - 2 Feb
includes taxes & fees
9/10 Wonderful! (1,539 reviews)
Good vibe
Reviewed on 7 Jan 2026

Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 2.046.121 ₫ per night from 19 Jan to 20 Jan
2.046.121 ₫
2.392.508 ₫ total
19 Jan - 20 Jan
includes taxes & fees
8/10 Very Good! (647 reviews)
The hotel and the room were very up-to-date, clean and inviting, the staff including the security guards (James, Norris and Mike) were all very professional, full of information about the area, restaurants and sights. They all went out of their way to help us and were so friendly. The breakfast was ...
Reviewed on 12 Jan 2026

Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 3.125.391 ₫ per night from 18 Jan to 19 Jan
3.125.391 ₫
3.716.901 ₫ total
18 Jan - 19 Jan
includes taxes & fees
9.2/10 Wonderful! (1,330 reviews)
The hotel was in a great location and the staff was super friendly. Rooms were clean and comfortable. The food was good. And we loved the kick back. Getting 3 drinks per person per night and a dinner snack was awesome!!! We would highly recommend this hotel to anyone.
Reviewed on 5 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit

St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game.

City Museum
You can spend an afternoon browsing the exhibits at City Museum during your trip to St. Louis. Experience the area's fascinating museums and great live music.

Citygarden
Explore the great outdoors at Citygarden, a lovely green space in St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game.


