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30 Oct - 1 Nov
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6 Nov - 8 Nov

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Our top choices for Isle of Palms hotels

A spacious living area with a high ceiling, a fireplace, and a bar area in the background.

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (613 reviews)
"Had a great experience while here. Rooms were clean and spacious. Will definitely stay here again."
United States
LISA
The price is 3.532.723 ₫
4.009.641 ₫ total
includes taxes & fees
13 Nov - 14 Nov
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
A modern restaurant with a bar area, wooden ceiling, and large windows.

2. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
4.5 star property
2.1 km from Isle of Palms
9.2 out of 10, Wonderful, (386 reviews)
"A beautiful place will stay there again"
United States
Brandy
The price is 4.107.427 ₫
4.661.930 ₫ total
includes taxes & fees
22 Nov - 23 Nov
Hilton Jacksonville at Mayo Clinic near Beaches
A hotel lobby with a bar area, seating arrangements, and a reception desk.

3. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,002 reviews)
"Loved the room, and the little cheese omelets at breakfast were good!"
United States
Kerry
The price is 3.066.810 ₫
3.480.831 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
A lobby with a reception desk, seating area, and a staircase.

4. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,020 reviews)
"Great bed and breakfast"
United States
Gregory
The price is 2.713.305 ₫
3.079.602 ₫ total
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.

5. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
3 km from Isle of Palms
9.2 out of 10, Wonderful, (667 reviews)
"The room was very clean and comfortable. It would be nice to have the breakfast time last longer than 9:00am though."
United States
Lana
The price is 3.178.443 ₫
3.607.533 ₫ total
includes taxes & fees
1 Nov - 2 Nov
TownePlace Suites by Marriott Jacksonville East
A spacious lobby with a glass floor, a reception desk, and a view of the ocean.

6. Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
8.8 out of 10, Excellent, (4,612 reviews)
"really enjoyed our stay"
United States
Lavorus
The price is 3.705.057 ₫
4.205.238 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Margaritaville Jacksonville Beach
An outdoor patio area with wicker furniture, a fire feature, and string lights.

7. Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
10.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was real nice rooms were clean. Bartender was real nice facilities looked amazing."
United States
Jarvon
The price is 3.072.495 ₫
3.487.281 ₫ total
includes taxes & fees
30 Oct - 31 Oct
Sheraton Jacksonville Hotel
An outdoor patio with seating, a fire pit, and string lights.

8. Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,185 reviews)
"Nice hotel"
United States
Becky
The price is 3.286.975 ₫
3.730.717 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Hyatt Place Jacksonville / St. Johns Town Center
A terrace with wooden tables and chairs, overlooking a beach and a pier.

9. Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
Oceanfront, 4.5 km from Isle of Palms
9.0 out of 10, Wonderful, (813 reviews)
"Lovely hotel"
United States
Ovidiu
The price is 4.371.005 ₫
4.961.090 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Springhill Suites By Marriott Jacksonville Beach Oceanfront
A modern outdoor seating area with white wicker chairs, a glass fire pit with burning wood, and a view of palm trees and a building in the background.

10. Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (595 reviews)
"always a great stay. although this is our second time staying and something was broken in the bathroom."
United States
ariel
The price is 3.721.104 ₫
4.223.453 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Element by Marriott Jacksonville Beach
Pool

11. Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
Oceanfront, 4.3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location, room was spacious and comfortable"
United States
Rachel
The price is 5.249.599 ₫
5.958.295 ₫ total
includes taxes & fees
11 Nov - 12 Nov
Four Points by Sheraton Jacksonville Beachfront
Exterior

12. Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.4 out of 10, Exceptional, (231 reviews)
"Wonderful stay!"
United States
Mandy
The price is 3.126.761 ₫
3.548.874 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Hyatt Studios Jacksonville/St Johns Town Center
A covered entrance with a dark tiled floor, white columns, and a green bench.

13. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,246 reviews)
"Great location"
United States
William Garita
The price is 3.053.114 ₫
3.465.285 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
A buffet with multiple self-service stations, including omelets and other prepared foods.

14. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
3.3 km from Isle of Palms
9.2 out of 10, Wonderful, (1,006 reviews)
"Great place to stay"
United States
Bobby
The price is 2.945.874 ₫
3.343.567 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Jacksonville Beach by IHG
A self-service beverage station with a refrigerated display and a coffee machine.

15. Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (975 reviews)
"The staff was very welcoming,and friendly ."
United States
Janice
The price is 2.829.073 ₫
3.210.998 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Tru By Hilton Jacksonville St Johns Town Center
A corridor with large windows, a patterned carpet, and a wooden bench.

16. Holiday Inn Jacksonville E 295 Baymeadows by IHG

Holiday Inn Jacksonville E 295 Baymeadows by IHG
3.0 star property
9.8 km from Isle of Palms
8.6 out of 10, Excellent, (1,002 reviews)
"Great Hotel"
United States
Josh
The price is 2.403.213 ₫
2.727.646 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Holiday Inn Jacksonville E 295 Baymeadows by IHG
A beach with a sandy shore, waves, and buildings in the background.

17. Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,006 reviews)
"Would stay again"
United States
Williams
The price is 3.147.175 ₫
3.572.045 ₫ total
includes taxes & fees
27 Oct - 28 Oct
Best Western Oceanfront
A modern dining area with wooden tables and chairs, pendant lighting, and artwork on the walls.

18. Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (996 reviews)
"friendly and helpful staff. Breakfast was very good."
United States
Daniel
The price is 3.272.763 ₫
3.714.587 ₫ total
includes taxes & fees
29 Oct - 30 Oct
Fairfield Inn & Suites by Marriott Jacksonville Beach
A living room with a sofa, chairs, a coffee table, a lamp, and a view of the ocean.

19. Dune House Hotel & Spa

Dune House Hotel & Spa
4.5 star property
6.7 km from Isle of Palms
8.8 out of 10, Excellent, (1,001 reviews)
"Location right on the beach with private access, use of property chairs, umbrellas and towels. Staff is immensely helpful. Coastal Farmer restaurant and bar is fabulous!"
United States
Tracy
The price is 5.400.769 ₫
7.241.036 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Dune House Hotel & Spa
A modern bar area with wooden accents, a variety of beverages, and seating arrangements.

20. Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway
3.0 star property
13.3 km from Isle of Palms
9.2 out of 10, Wonderful, (751 reviews)
"Lovely stay"
United States
Chloie Marie
The price is 2.306.309 ₫
2.617.660 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott Jacksonville I-295/East Beltway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Isle of Palms

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
613 reviews
View
A lobby with a reception desk, seating area, and a staircase.
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
9.0
Wonderful
1,020 reviews
View
A hotel lobby with a bar area, seating arrangements, and a reception desk.
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,002 reviews
View
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
667 reviews
View
A beach with a sandy shore, waves, and buildings in the background.
Best Western Oceanfront
3.0 star property
9.0
Wonderful
1,006 reviews
View

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.
A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Florida Theatre and Jacksonville Museum of Modern Art are top sights in Downtown Jacksonville, and you should be sure to explore the stunning river views. Hop aboard the metro at Riverplace Station or Kings Avenue Station to see more sights in the area.

A coastal cityscape at dusk with a prominent clock tower, waterfront, and historic buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

A sunset over a beach with waves and a pier.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

A city skyline at night with illuminated buildings and a bridge reflecting on the water.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

A golf course with a pond, trees, and buildings in the background.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms Hotel Reviews

Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

10/10 Excellent
"The breakfast was absolutely phenomenal! The wait staff were friendly. Front desk were very helpful & kind. We had a very pleasant stay. Definitely recommend!"
Sherrie 2-night trip
Posted 2 hours ago
Embassy Suites by Hilton Jacksonville Baymeadows

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
How many hotels should I expect to find in Isle of Palms?
Expedia has 37 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.