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Check prices for these dates

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

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Our top choices for Louisville Science Center hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,009 reviews)
"Had a great stay! "
United States
Amanda
The price is 2.909.966 ₫
3.423.865 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Homewood Suites by Hilton Louisville Downtown, KY
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town."
United States
Jason
The price is 4.009.802 ₫
4.849.712 ₫ total
includes taxes & fees
21 Jun - 22 Jun
21c Museum Hotel Louisville
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Had a wonderful stay and the staff were so friendly!"
United States
Tanya
The price is 4.131.303 ₫
4.860.837 ₫ total
includes taxes & fees
28 May - 29 May
The Grady
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (467 reviews)
"Bar and restaurant were amazing!!"
Canada
Cheryl
The price is 4.847.396 ₫
5.703.447 ₫ total
includes taxes & fees
14 Jun - 15 Jun
Hotel Distil, Autograph Collection
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (610 reviews)
"Great place to stay! I would definitely stay here again!"
United States
Dana Jean
The price is 2.661.956 ₫
3.132.059 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Towneplace Suites By Marriott Louisville Downtown
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,892 reviews)
"Great place to stay, perfect location "
United States
Ben
The price is 4.722.995 ₫
5.556.899 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Omni Louisville Hotel
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (108 reviews)
"Very nice and quiet hotel."
United States
Sandy
The price is 5.165.249 ₫
6.077.432 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (121 reviews)
"Great place near quite a few shops and restaurants. Close enough to downtown. Breakfast was nice and everyone was very welcoming."
United States
Anissa
The price is 4.394.599 ₫
4.965.734 ₫ total
includes taxes & fees
27 May - 28 May
Market Street Inn
Interior entrance

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (23 reviews)
"The property is beautiful. Our room was lovely—very clean and comfortable. The seating in our room was perfect for reading, and the balcony an extra treat. Allen was so gracious and helpful. The location was great for dinner plans and a short easy drive to Churchill Downs. Breakfast was delicious—especially the biscuits and gravy. And, the young lady that served us breakfast was very nice and helpful. I’d recommend this Bed and Breakfast to anyone who is planning to spend time in...
United States
Nancy
The price is 8.170.360 ₫
9.483.338 ₫ total
includes taxes & fees
27 May - 28 May
Louisville Bourbon Inn
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,228 reviews)
"Breakfast menu was great, bartender, and drinks were wonderful!"
United States
hannah
The price is 5.433.804 ₫
6.393.414 ₫ total
includes taxes & fees
31 May - 1 Jun
The Brown Hotel
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,008 reviews)
"Loved our stay!"
United States
Rebecca
The price is 3.163.774 ₫
3.722.496 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Cambria Hotel Louisville Downtown-Whiskey Row
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (759 reviews)
"The Moxy is a great hotel, very cool decor. Great location and a very helpful staff. Rooms are quiet and there is a nice bar in the lobby."
United States
Carrie
The price is 2.556.532 ₫
3.008.016 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Moxy Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (135 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is 2.829.073 ₫
4.660.318 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Stellar Suites
4 restaurants; breakfast, lunch, and dinner served

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,191 reviews)
"The staff was super friendly and the stay was very comfortable!"
United States
James
The price is 3.615.242 ₫
4.253.693 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Galt House Hotel Trademark Collection by Wyndham
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,247 reviews)
"Clean, great staff!"
United States
Natali
The price is 2.958.636 ₫
3.481.131 ₫ total
includes taxes & fees
9 Jun - 10 Jun
Embassy Suites Louisville Downtown
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,741 reviews)
"Room was clean, staff was helpful and breakfast was excellent"
United States
Chic
The price is 2.661.956 ₫
3.132.057 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Holiday Inn Express & Suites Louisville Downtown by IHG
2 restaurants; breakfast and dinner served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,021 reviews)
"Excellent location and clean hotel!"
United States
Monica
The price is 3.436.822 ₫
4.043.765 ₫ total
includes taxes & fees
27 May - 28 May
Tempo By Hilton Louisville Downtown Nulu
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
2.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.6 out of 10, Exceptional, (121 reviews)
"The staff and breakfast served was excellent. Amazing time, I will come back next time!!"
United States
Raman
The price is 3.764.164 ₫
4.369.034 ₫ total
includes taxes & fees
3 Jun - 4 Jun
DuPont Mansion Bed & Breakfast
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Bar was great."
United Kingdom
Pete
The price is 5.190.551 ₫
6.107.202 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Louisville Marriott Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,093 reviews)
"Adorable rooms and great spaces in the lobby to work. "
United States
Marissa
The price is 3.558.060 ₫
4.186.413 ₫ total
includes taxes & fees
14 Jun - 15 Jun
Hotel Genevieve part of JdV by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,009 reviews
View
Front of property
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,002 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,004 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
467 reviews
View
Property amenity
Towneplace Suites By Marriott Louisville Downtown
3.0 star property
9.2
Wonderful
610 reviews
View

Top Louisville Science Center Hotel Reviews

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown

10/10 Excellent
"The bed slept real good"
Yvonne 3-night trip
Posted 1 hour ago
Hilton Garden Inn Louisville Downtown

Hotels near other Louisville Science Center attractions

Louisville Slugger Museum

4.6/5 (2,299 reviews)
You can spend an afternoon studying the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 268 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 268 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.