The Best Hotels Closest to Louisville Science Center in Louisville - 2026 Updated Prices

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, large windows, and classic furniture.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

1. The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

Meghan

3.241.865 ₫

3.814.379 ₫ total

includes taxes & fees

10 Nov - 11 Nov

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

2. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Louisville Science Center

Anthony

6.139.096 ₫

7.223.261 ₫ total

includes taxes & fees

29 Oct - 30 Oct

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A living room with a sofa, a fireplace, a staircase, and a chandelier.

An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

3. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

Casey

3.704.153 ₫

4.299.410 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A swimming pool with lounge chairs and a view of the city.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

4. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

Kelly

3.189.882 ₫

3.753.215 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern bar area with a circular bar, multiple seating options, and a large screen.

A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

A modern lobby with a fireplace, seating area, and a reception desk.

A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

5. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Louisville Science Center

William

2.794.176 ₫

3.287.627 ₫ total

includes taxes & fees

9 Nov - 10 Nov

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

A building with a sign reading "THE GRADY" at the entrance.

6. The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

Bruce

4.808.164 ₫

5.657.285 ₫ total

includes taxes & fees

18 Oct - 19 Oct

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.

7. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

Addison

3.168.616 ₫

3.728.193 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A modern interior with a fireplace, bookshelves, and seating areas.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

A lobby with a marble floor, a reception desk, and a large chandelier.

8. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Louisville Science Center

Samantha

6.571.488 ₫

7.732.012 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

9. Stellar Suites

East Market District, 2.2 km from Louisville Science Center

Kevin

3.052.637 ₫

4.894.529 ₫ total

includes taxes & fees

4 Nov - 5 Nov

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern hotel room with a large bed, a city view, and a unique headboard design.

A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Louisville Science Center

Cameron

4.657.228 ₫

5.479.694 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A covered patio with a stone wall, a glass table, and a bench.

A stone house with a balcony, a front door, and a staircase leading to the entrance.

A grand room with a fireplace, a staircase, and a chandelier.

11. Central Park Bed & Breakfast

Old Louisville, 3 km from Louisville Science Center

Brittany

4.418.161 ₫

5.128.347 ₫ total

includes taxes & fees

10 Nov - 11 Nov

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

12. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Louisville Science Center

Matt

4.156.337 ₫

5.019.707 ₫ total

includes taxes & fees

8 Nov - 9 Nov

An outdoor seating area with wicker furniture and a fire pit.

A modern lounge area with seating, tables, and a view of the city through large windows.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

Derek

2.716.560 ₫

3.196.306 ₫ total

includes taxes & fees

5 Nov - 6 Nov

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

A modern coffee shop interior with a central island, wooden counter, and large windows.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

14. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Dolores

3.514.576 ₫

4.135.249 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A modern living room with a sofa, ottomans, a coffee table, and a rug.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

15. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Bryan

3.319.552 ₫

3.905.783 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.

16. AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

Jen

3.702.283 ₫

4.356.106 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A balcony with a view of a river, a bridge, and a cityscape.

17. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

Saud

3.764.061 ₫

4.428.794 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

A brightly lit grocery store with yellow shelving and a central checkout counter.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

18. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

Tyler

3.829.056 ₫

4.505.267 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

A modern hotel room with a living area, a dining area, and a bedroom.

A hotel dining area with long tables, booths, and a bar.

19. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Frances

3.797.492 ₫

4.468.128 ₫ total

includes taxes & fees

9 Nov - 10 Nov

A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

A reception area with marble counters, modern pendant lighting, and potted orchids.

20. Louisville Marriott Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Veronica

5.776.539 ₫

6.796.674 ₫ total

includes taxes & fees

7 Nov - 8 Nov

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Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
The Brown Hotel	9.4 Exceptional 1,359 reviews	View
Hotel Distil, Autograph Collection	9.6 Exceptional 508 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 148 reviews	View
Homewood Suites by Hilton Louisville Downtown, KY	9.4 Exceptional 1,002 reviews	View
Cambria Hotel Louisville Downtown-Whiskey Row	9.4 Exceptional 1,004 reviews	View

Top Louisville Science Center Hotel Reviews

Courtyard by Marriott Louisville Downtown

8/10 Good

"wonderful location and service"

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent

"overall everything about this property is good."

Econo Lodge Louisville Downtown

8/10 Good

"location was good."

Hyatt Regency Louisville

10/10 Excellent

"This hotel was beautiful, clean and well kept. The staff were very helpful during our stay providing directions to local areas we needed to go, and giving us umbrellas to use."

Cambria Hotel Louisville Downtown-Whiskey Row

10/10 Excellent

"Great hotel!"

Towneplace Suites By Marriott Louisville Downtown

8/10 Good

"Staff were great. Breakfast was good. Only is was the fan in the bathroom. It had a banging noise coming from it and if you left the door open it would keep you awake."

Holiday Inn Louisville Downtown by IHG

8/10 Good

"The room was very small. Had hoped that myself and husband could work remote in room, but that was impossible due to tiny space. He was able to work downstairs in lobby, but not ideal. Unable to get served at on-site restaurant. One person taking orders, cooking and serving during busy time of day. The person's working at checking and in on-site bar area were very helpful. Coffee and water were not kept filled in lobby area. A little disappointed in this. Good location near 4th Street Live area. Parking location is across the street if you don't want to pay valet fee."

Embassy Suites Louisville Downtown

10/10 Excellent

"It was clean, quite and there is plenty of entertainment close by."

Moxy Louisville Downtown

10/10 Excellent

"Amazing experience, everyone was helpful and the space was beautiful-- great photo opportunities everywhere and conveniently located. parking was not super far but did need about 5 minutes to walk to and from"

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

You can spend an afternoon studying the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

You can spend an afternoon browsing the exhibits at Muhammad Ali Center during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

You can spend an afternoon exploring the galleries in Frazier International History Museum during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy an outing to Kentucky Center for the Performing Arts during your stay in Louisville. Stroll along the riverfront or attend a sporting event in the area.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

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Our top choices for Louisville Science Center hotels

1. The Brown Hotel

2. Hotel Distil, Autograph Collection

3. DuPont Mansion Bed & Breakfast

4. Homewood Suites by Hilton Louisville Downtown, KY

5. Cambria Hotel Louisville Downtown-Whiskey Row

6. The Grady

7. Tempo By Hilton Louisville Downtown Nulu

8. Omni Louisville Hotel

9. Stellar Suites

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

11. Central Park Bed & Breakfast

12. 21c Museum Hotel Louisville

13. Towneplace Suites By Marriott Louisville Downtown

14. Aloft by Marriott Louisville Downtown

15. Moxy Louisville Downtown

16. AC Hotel Louisville Downtown

17. Galt House Hotel Trademark Collection by Wyndham

18. Hotel Genevieve part of JdV by Hyatt

19. Embassy Suites Louisville Downtown

20. Louisville Marriott Downtown

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

Courtyard by Marriott Louisville Downtown

Galt House Hotel Trademark Collection by Wyndham

Econo Lodge Louisville Downtown

Hyatt Regency Louisville

Cambria Hotel Louisville Downtown-Whiskey Row

Towneplace Suites By Marriott Louisville Downtown

Holiday Inn Louisville Downtown by IHG

Embassy Suites Louisville Downtown

Moxy Louisville Downtown

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions

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