Mackenzie Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Mackenzie

Find the best Mackenzie areas and neighborhoods for the activities you enjoy most. Learn more about Mackenzie
Downtown St. Louis

Downtown St. Louis

3 out of top 10 points of interest in this area
4.5/5(18 area reviews)

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Find hotels in Downtown St. Louis

Top hotels in Mackenzie

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 3.334.188 ₫ per night from 25 May to 26 May
3.334.188 ₫
3.931.974 ₫ total
25 May - 26 May
includes taxes & fees
8.6/10 Excellent! (4,055 reviews)
Missed our room for housekeeping which is minor, toilet seat was broken but they fixed it promptly, overall decor is dated, no recycling, otherwise fine.

Reviewed on 7 May 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 2.615.225 ₫ per night from 17 May to 18 May
2.615.225 ₫
3.053.290 ₫ total
17 May - 18 May
includes taxes & fees
8.8/10 Excellent! (3,189 reviews)
Excellent breakfast Receptionist not too friendly

Reviewed on 6 May 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 4.449.094 ₫ per night from 10 May to 11 May
4.449.094 ₫
5.333.911 ₫ total
10 May - 11 May
includes taxes & fees
9/10 Wonderful! (1,821 reviews)
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.

Reviewed on 6 May 2026

21C Museum Hotel St Louis
See all 1,875 properties in Mackenzie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mackenzie holiday package cost?
Much less than you might think — from a low , actually! By combining hotels, flights and car rentals into a custom-built package, your trip to Mackenzie is just clicks away.
How do I get a cheap travel package to Mackenzie?
You'll save piles of cash if you combine your flights, car rentals and hotels into a Mackenzie holiday package. Sometimes cheap means fewer choices. But not with Expedia. We offer over 550 partner airlines and 1null000null000 hotels across the globe, which means you'll always have plenty of variety to choose from. Eager to save even more? Add some popular activities to your package deal and unlock even bigger discounts! After all, travel is about more than simply getting to your destination.
Where should I stay in Mackenzie?
Most who travel to Mackenzie include both St. Louis Zoo and Cathedral Basilica of St. Louis on their itineraries. Why not select a hotel that's close to these fantastic attractions?
How far in advance should I book my Mackenzie holiday?
Savvy travellers will likely want to reserve their seats early. You can usually start comparing international fares on Expedia up to 12 months before your flight. If you've left things to the last minute, don't stress. Budget prices sometimes occur just weeks before departure.
What does an Expedia Mackenzie travel package include?
Expedia has all you need to arrange your Mackenzie trip, but what goes into your package is your choice. Pick from any combination of hotels, flights and rental cars. After some activities to keep you on the move? Once you've made your booking, you can add them on too. No matter your budget or style, there's a package to match your needs.
What should I know before booking a Mackenzie travel package?
Locking in all the parts of your holiday together is one of the easiest ways to save. Bundle car rentals, airfares and hotels into a handy package. But your options don't end at hotels. Expedia has all kinds of properties, including holiday rentals like beachfront villas and serviced residences. The list goes on!
Can I choose my airline with a Mackenzie Expedia holiday package?
Expedia has access to more than 550 partner airlines worldwide, so you definitely can. Simply choose your preferred air carrier and create the perfect Mackenzie holiday.
If I'm not able to travel, can I cancel my Mackenzie holiday package?
Because we understand life can throw you a few curveballs, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you've booked your Mackenzie holiday package in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.

Popular places to visit

Union Station, St. Louis, MO

St. Louis Union Station

You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Union Station
Gateway Arch

Gateway Arch

Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

Why not visit the animals who live at St. Louis Zoo and see why this is a favourite attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.

St. Louis Zoo