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Top hotels in Medora

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

3 out of 5
3559 College Avenue Alton IL
Fully refundable
The price is 2.218.351 ₫ per night from 21 Dec to 22 Dec
2.218.351 ₫
2.528.476 ₫ total
21 Dec - 22 Dec
includes taxes & fees
7.6/10 Good! (756 reviews)
Was a great stay !!!!

Reviewed on 16 Nov 2025

The Great Rivers, an Ascend Collection Hotel
Comfort Inn Alton near I-255

Comfort Inn Alton near I-255

2.5 out of 5
11 Crossroads Ct Alton IL
Fully refundableReserve now, pay when you stay
The price is 2.082.835 ₫ per night from 30 Nov to 1 Dec
2.082.835 ₫
2.373.905 ₫ total
30 Nov - 1 Dec
includes taxes & fees
7.6/10 Good! (497 reviews)
The room was very clean. The staff was fantastic. It was quiet and I was able to relax comfortably and got a great nights sleep.

Reviewed on 25 Nov 2025

Comfort Inn Alton near I-255
Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton

2.5 out of 5
1904 Homer M Adams Parkway Alton IL
Fully refundableReserve now, pay when you stay
The price is 3.038.285 ₫ per night from 19 Dec to 20 Dec
3.038.285 ₫
3.463.170 ₫ total
19 Dec - 20 Dec
includes taxes & fees
9/10 Wonderful! (636 reviews)
We reserved a handicap accessible room. It was extremely nice and roomy. Bathroom was large as well. Our stay was great and and room was clean.

Reviewed on 17 Nov 2025

Hampton Inn & Suites St. Louis/Alton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.