What is Mission Bay like?

Travellers will be sure to enjoy their time in San Francisco's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Chase Center while you're in the neighbourhood.

How many hotels will I be able to find in Mission Bay?

When you want to find places to stay in San Francisco, start by booking one of Expedia's 5 hotels and other accommodation options in Mission Bay.

If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals available in Mission Bay.

What are the top things to see and do in Mission Bay?

Chase Center, PIER 48 - Lot #39 and Lefty O'Doul Bridge are just a few attractions to check out in Mission Bay. A visit to Lucky Strike San Francisco is also worth the trip while you're discovering the neighbourhood. Oracle Park and Pier 39 are some popular places to visit in the area around Mission Bay. When you're sightseeing in San Francisco, Bottom of the Hill and California College of the Arts are also worth a stop.

How can I get around Mission Bay and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at UCSF/Chase Center Stop, Mission Rock Station or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.

The Best Hotels in Mission Bay, San Francisco - 2026 Updated Prices

A coastal cityscape with a large body of water, several ships, and ongoing construction on a prominent red building.

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Our top choices for Mission Bay hotels

A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.

1. LUMA Hotel San Francisco

Mission Bay

ninos

6.490.479 ₫ total

includes taxes & fees

23 Nov - 24 Nov

An outdoor seating area with wicker furniture and a fire feature, adjacent to a bar and dining area with modern decor.

2. Hyatt Place San Francisco Downtown

0.9 km from Mission Bay

Shea

5.125.099 ₫ total

includes taxes & fees

25 Nov - 26 Nov

A modern interior with a central escalator, multiple levels, and a distinctive sculpture.

3. Hyatt Regency San Francisco

Financial District, 2.6 km from Mission Bay

Joceline

6.285.058 ₫ total

includes taxes & fees

21 Nov - 22 Nov

A Holiday Inn hotel with a modern design, featuring a large number of uniformly sized windows and a flat roof.

4. Holiday Inn Golden Gateway by IHG

Nob Hill, 3.4 km from Mission Bay

Sangeeta Harinarain

3.585.460 ₫ total

includes taxes & fees

29 Nov - 30 Nov

A tall hotel with a modern design, a prominent entrance, and a view of the city skyline.

5. Hilton San Francisco Financial District

Financial District, 2.9 km from Mission Bay

Huy

2.747.674 ₫ total

includes taxes & fees

29 Nov - 30 Nov

A modern building with a sign reading "RIU Plaza Fisherman's Wharf".

6. Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf, 4.5 km from Mission Bay

Patricia

5.030.373 ₫ total

includes taxes & fees

13 Dec - 14 Dec

A hotel with a modern design, featuring a prominent 'PARC 55' sign, multiple floors, and a corner location with a visible street view.

7. Parc 55 San Francisco - A Hilton Hotel

Union Square, 2.2 km from Mission Bay

Joseph

4.430.935 ₫ total

includes taxes & fees

29 Nov - 30 Nov

The exterior of the Chancellor Hotel with a glass entrance, a signboard, and an ATM on the right.

8. Chancellor Hotel on Union Square

2.5 km from Mission Bay

Jamie

3.123.023 ₫ total

includes taxes & fees

22 Nov - 23 Nov

A modern living room with a city view, a round coffee table, and a sofa.

9. Hotel Nikko San Francisco

Union Square, 2.3 km from Mission Bay

Jessica

6.529.792 ₫ total

includes taxes & fees

22 Nov - 23 Nov

A rooftop terrace with a table and chairs, a potted plant, and a view of tall buildings.

10. Club Quarters Hotel Embarcadero, San Francisco

Financial District, 2.8 km from Mission Bay

Stephen

3.464.940 ₫ total

includes taxes & fees

20 Nov - 21 Nov

A hotel lobby with a wooden floor, patterned chairs, a small table with a candle, and a decorative railing.

11. Galleria Park Hotel

Financial District, 2.4 km from Mission Bay

Kari

4.363.029 ₫ total

includes taxes & fees

27 Nov - 28 Nov

A historic building with a prominent corner entrance, a tram line, and a flag.

12. Stanford Court San Francisco

Nob Hill, 2.8 km from Mission Bay

naman

5.649.408 ₫ total

includes taxes & fees

13 Nov - 14 Nov

A multi-story building with a prominent corner entrance, large windows, and a visible ground-level cafe.

13. King George Hotel

Union Square, 2.4 km from Mission Bay

Jessica J

3.314.495 ₫ total

includes taxes & fees

28 Nov - 29 Nov

A hotel room with two beds, a nightstand with a vase of flowers, and a wooden wall with a hanging light.

14. Hotel 32One

Union Square, 2.5 km from Mission Bay

Braelyn

2.974.258 ₫ total

includes taxes & fees

25 Nov - 26 Nov

A hotel room with a large window offering a cityscape view, a lamp, and a chair.

15. Comfort Inn by the Bay

Cow Hollow, 4.5 km from Mission Bay

Crystal

3.109.409 ₫ total

includes taxes & fees

13 Dec - 14 Dec

A hotel courtyard with a swimming pool, lounge chairs, and potted plants.

16. Handlery Union Square Hotel

Union Square, 2.4 km from Mission Bay

Anna

4.496.890 ₫ total

includes taxes & fees

13 Dec - 14 Dec

A high-rise room with a city view, a sofa, two chairs, a small table, and a patterned rug.

17. Hilton San Francisco Union Square

Union Square, 2.4 km from Mission Bay

Emily

4.323.644 ₫ total

includes taxes & fees

25 Nov - 26 Nov

A lobby with a chandelier, seating area, and large mirrors.

18. Beacon Grand, A Union Square Hotel

Union Square, 2.5 km from Mission Bay

Peggy

6.137.608 ₫ total

includes taxes & fees

25 Nov - 26 Nov

A modern lounge area with seating, a bar, and a large window.

19. Hotel Zephyr San Francisco

Fisherman's Wharf, 4.5 km from Mission Bay

Adriana

4.834.761 ₫ total

includes taxes & fees

29 Nov - 30 Nov

A modern bar area with a long wooden counter, multiple bar stools, and a variety of bottles and glasses.

20. Hotel Emblem San Francisco

2.6 km from Mission Bay

Jessica

3.892.880 ₫ total

includes taxes & fees

22 Nov - 23 Nov

View all properties

Compare top hotels in Mission Bay

LUMA Hotel San Francisco 4.0 star property Mission Bay View	Hyatt Place San Francisco Downtown 3.0 star property 0.9 km from Mission Bay View	Hyatt Regency San Francisco 4.0 star property Financial District, 2.6 km from Mission Bay View	Holiday Inn Golden Gateway by IHG 3.5 star property Nob Hill, 3.4 km from Mission Bay View	Hilton San Francisco Financial District 4.0 star property Financial District, 2.9 km from Mission Bay View
9.6 Exceptional 2,692 reviews	9.4 Exceptional 2,370 reviews	9.4 Exceptional 2,577 reviews	9.0 Wonderful 6,486 reviews	8.8 Excellent 3,439 reviews
The price is 5.514.535 ₫ 6.490.479 ₫ total includes taxes & fees 23 Nov - 24 Nov	The price is 4.354.560 ₫ 5.125.099 ₫ total includes taxes & fees 25 Nov - 26 Nov	The price is 4.338.528 ₫ 6.285.058 ₫ total includes taxes & fees 21 Nov - 22 Nov	The price is 3.046.400 ₫ 3.585.460 ₫ total includes taxes & fees 29 Nov - 30 Nov	The price is 2.334.572 ₫ 2.747.674 ₫ total includes taxes & fees 29 Nov - 30 Nov
No Breakfast included No Pool No Spa No Pet-friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included No Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	No Breakfast included Yes, Pool No Spa No Pet-friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet-friendly No WiFi included Yes, Parking

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

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A city street with tall buildings, flags, and cars.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

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A cityscape with a prominent skyscraper, a bridge, and a mix of modern and historic buildings.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

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Top Mission Bay Hotel Reviews

Handlery Union Square Hotel

10/10 Excellent

"No fuss, easy access."

Parc 55 San Francisco - A Hilton Hotel

8/10 Good

"All in all the hotel was nice. I have two complaints. The woman checking us in was very curt, appeared annoyed and never smiled. Perhaps she was having a bad day. She made things not start well. The bar experience was nice with great staff but the cocktails were over priced. $22 for a single cocktail? Seriously? Yes we would go back because the location was ideal."

Search Hotels in Mission Bay, San Francisco

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Our top choices for Mission Bay hotels

1. LUMA Hotel San Francisco

2. Hyatt Place San Francisco Downtown

3. Hyatt Regency San Francisco

4. Holiday Inn Golden Gateway by IHG

5. Hilton San Francisco Financial District

6. Hotel Riu Plaza Fisherman's Wharf

7. Parc 55 San Francisco - A Hilton Hotel

8. Chancellor Hotel on Union Square

9. Hotel Nikko San Francisco

10. Club Quarters Hotel Embarcadero, San Francisco

11. Galleria Park Hotel

12. Stanford Court San Francisco

13. King George Hotel

14. Hotel 32One

15. Comfort Inn by the Bay

16. Handlery Union Square Hotel

17. Hilton San Francisco Union Square

18. Beacon Grand, A Union Square Hotel

19. Hotel Zephyr San Francisco

20. Hotel Emblem San Francisco

Compare top hotels in Mission Bay

LUMA Hotel San Francisco

Hyatt Place San Francisco Downtown

Hyatt Regency San Francisco

Holiday Inn Golden Gateway by IHG

Hilton San Francisco Financial District

Where to stay in Mission Bay

Union Square

Downtown San Francisco

Fisherman's Wharf

South of Market

Nob Hill

Top Mission Bay Hotel Reviews

Handlery Union Square Hotel

Frequently asked questions

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