Search Hotels in Downtown South San Francisco, San Francisco

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Downtown South San Francisco, San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very good, (2008)
"Great place to stay "
The price is 2.667.932 ₫
3.133.986 ₫ total
includes taxes & fees
26 Oct - 27 Oct
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

2.0 star property
8.8 out of 10, Excellent, (961)
"I was surprised by how friendly the front desk guy was when I checked in after midnight, and also by how clean the room was, for the price I would say this is unbeatable for the area, I will be back."
The price is 2.729.916 ₫
3.198.618 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Airport Inn

Inn By The SFO

2.0 star property
7.8 out of 10, Good, (1001)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
Inn By The SFO

Miller Apartments

2.0 star property
7.8 out of 10, Good, (14)
"Ty"
The price is 1.648.500 ₫
3.924.914 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Miller Apartments

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
9.0 out of 10, Wonderful, (2152)
"Had a wonderful stay, staff was wonderful."
The price is 3.642.648 ₫
5.079.382 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Hotel North Beach

2.0 star property
7.0 out of 10, Good, (1005)
"Shops great food cool vibe this the coolest place love it "
Hotel North Beach

Half Moon Bay Lodge

3.0 star property
9.0 out of 10, Wonderful, (1004)
"Definitely would stay there again. Felt like being with family."
The price is 4.443.828 ₫
5.205.148 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Half Moon Bay Lodge

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
8.6 out of 10, Excellent, (1416)
"Great place to stay."
The price is 3.560.760 ₫
5.277.528 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Centric Fisherman's Wharf San Francisco

Hotel Caza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (3792)
"very nice place to stay"
The price is 3.223.675 ₫
5.004.762 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Hotel Caza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6919)
"Very clean, wonderful staff, amazing breakfast, and close to all fishermen’s Wharf activities!!"
The price is 3.881.035 ₫
5.654.475 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Hotel Riu Plaza Fisherman's Wharf

FOUND Hotel Carlton, Nob Hill

2.0 star property
8.6 out of 10, Excellent, (929)
"Great staff- great locations"
The price is 2.007.082 ₫
2.362.235 ₫ total
includes taxes & fees
2 Nov - 3 Nov
FOUND Hotel Carlton, Nob Hill

The Lodge at Tiburon

3.5 star property
8.8 out of 10, Excellent, (1000)
"Overall a great stay. "
The price is 5.358.284 ₫
6.751.575 ₫ total
includes taxes & fees
2 Nov - 3 Nov
The Lodge at Tiburon

Hotel Majestic

3.5 star property
9.2 out of 10, Wonderful, (1010)
"Easy access to a lot of things, nice and clean and good staff!"
The price is 4.228.639 ₫
4.926.682 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Hotel Majestic

The Marina Inn on San Francisco Bay

2.5 star property
8.6 out of 10, Excellent, (2118)
"Great value, convenient location, & the staff was very nice. "
The Marina Inn on San Francisco Bay

Hotel Nikko San Francisco

4.5 star property
9.4 out of 10, Exceptional, (2562)
"Everything from the staff to the location was excellent. Will definitely stay here again."
The price is 5.134.088 ₫
7.255.510 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Hotel Nikko San Francisco

Hotel Zephyr San Francisco

4.0 star property
8.6 out of 10, Excellent, (2222)
"Great location"
The price is 5.631.276 ₫
7.559.068 ₫ total
includes taxes & fees
6 Oct - 7 Oct
Hotel Zephyr San Francisco

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1317)
"The location was great"
The price is 3.560.760 ₫
4.733.833 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Regency San Francisco Airport

SFO El Rancho Inn SureStay Collection by Best Western

3.0 star property
8.4 out of 10, Very good, (2854)
"It is very close to the airport and good place to stay if you have early flight "
The price is 2.892.128 ₫
3.346.048 ₫ total
includes taxes & fees
10 Oct - 11 Oct
SFO El Rancho Inn SureStay Collection by Best Western

Handlery Union Square Hotel

3.5 star property
8.8 out of 10, Excellent, (2723)
"Enjoyed our stay"
The price is 4.822.456 ₫
5.675.789 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Handlery Union Square Hotel

The Dylan at SFO

3.0 star property
9.2 out of 10, Wonderful, (1756)
"Nice place to stay "
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Downtown South San Francisco Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.

How many hotels should I expect to find in the Downtown South San Francisco area?

When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.

What can I see and do in this South San Francisco neighbourhood?

See's Candies, Cinemark Century at Tanforan and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.