San Luis Obispo Wine Country Holidays

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Photo by Anthony Hilario

Where to stay in San Luis Obispo Wine Country

Find the best San Luis Obispo Wine Country areas and neighborhoods for the activities you enjoy most. Learn more about San Luis Obispo Wine Country
Downtown San Luis Obispo

Downtown San Luis Obispo

3 out of top 10 points of interest in this area
4.5/5(2 area reviews)

If you're spending some time in Downtown San Luis Obispo, Downtown SLO Farmers' Market and Mission San Luis Obispo de Tolosa are top sights worth seeing.

Find hotels in Downtown San Luis Obispo

Top hotels in San Luis Obispo Wine Country

Madonna Inn

Madonna Inn

3.5 out of 5
100 Madonna Road San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is 3.264.424 ₫ per night from 16 Apr to 17 Apr
3.264.424 ₫
4.601.521 ₫ total
16 Apr - 17 Apr
includes taxes & fees
9.2/10 Wonderful! (1,418 reviews)
Everything was great

Reviewed on 10 Apr 2026

Madonna Inn
Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

3 out of 5
1631 Monterey St San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is 3.411.850 ₫ per night from 26 Apr to 27 Apr
3.411.850 ₫
4.537.253 ₫ total
26 Apr - 27 Apr
includes taxes & fees
9.4/10 Exceptional! (1,381 reviews)
Clean room

Reviewed on 7 Apr 2026

Quality Suites Downtown San Luis Obispo
Spyglass Inn

Spyglass Inn

3 out of 5
2705 Spyglass Dr Pismo Beach CA
Fully refundableReserve now, pay when you stay
The price is 3.893.615 ₫ per night from 3 May to 4 May
3.893.615 ₫
4.465.781 ₫ total
3 May - 4 May
includes taxes & fees
8.8/10 Excellent! (1,529 reviews)
Clean and pretty room. Great customer service in front office. Near to ocean and beautiful greenery

Reviewed on 8 Apr 2026

Spyglass Inn
See all 404 properties in San Luis Obispo Wine Country
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

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California Polytechnic State University, San Luis Obispo

Enjoy the student vibe at California Polytechnic State University, San Luis Obispo during your visit to San Luis Obispo. Stroll along the area's seaside or simply savour its top-notch restaurants.

California Polytechnic State University, San Luis Obispo
Avila Hot Springs

Avila Hot Springs

Explore the great outdoors at Avila Hot Springs and enjoy the beautiful sunsets during your trip to San Luis Obispo. Wander through the beautiful beaches and seaside in this family-friendly area.

Avila Hot Springs
Fremont Theater

Fremont Theater

You can enjoy a show at Fremont Theater during your trip to San Luis Obispo. Wander the beautiful beaches or discover the area's beautiful sunsets.

Fremont Theater

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