South Central Houston Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Downtown Houston
3 out of top 10 points of interest in this area
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.
Texas Medical Center
1 out of top 10 points of interest in this area
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Top hotels in South Central Houston
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
2.741.606 ₫
3.237.744 ₫ total
19 Sept - 20 Sept
includes taxes & fees
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
4.986.363 ₫
6.858.064 ₫ total
12 Sept - 13 Sept
includes taxes & fees
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
3.549.082 ₫
4.417.542 ₫ total
27 Sept - 28 Sept
includes taxes & fees
9.2/10 Wonderful! (1,189 reviews)
"The hotel was very clean, and the installations were well maintained. The location is amazing for visiting the museum district and even has some commercial food options in the surroundings. I was very pleased with my stay."
Reviewed on 11 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a South Central Houston holiday package cost?
Starting from a low , a holiday package is your passport to inexpensive travel. Custom build your South Central Houston getaway by selecting from our huge range of hotels, flights and rental cars.
How do I get a cheap travel package to South Central Houston?
Combining your flight and hotel with Expedia won't just save you time — it'll save you a tidy sum too. A South Central Houston holiday package makes it easy to put together the perfect trip. With more than 550 airlines across the world to choose from, finding flights that suit your busy schedule won't be a problem. On top of that, we have over 1null000null000 hotels globally to select from. Now that's what we call choice. Whatever your budget, Expedia will help show you the world.
How far in advance should I book my South Central Houston holiday?
While not all air carriers release ticket prices early, you can usually compare international fares on Expedia up to 12 months in advance. This is the time you can nab some incredible deals. If you've left everything to the last minute, you might get lucky. Low prices sometimes appear just weeks before departure.
What does an Expedia South Central Houston travel package include?
That depends on what you're after. If you're travelling by yourself, you might decide to bundle hotels and flights. Taking the whole family to South Central Houston? A travel package including hotels, flights and rental cars might suit you better. Expedia gives you the flexibility to build your own travel package.
What should I know before booking a South Central Houston travel package?
Design deals that suit your budget with an Expedia package. Flights, hotels, rental cars — we have everything you need to plan your escape. You'll save a packet just by combining your bookings. Whether you're embarking on a ski trip or drinking cocktails on a beach, your dream holiday is just a few clicks away.
Can I choose my airline with a South Central Houston Expedia holiday package?
Yes, you sure can. We offer more than 550 airline partners worldwide, so select the carrier that matches your budget needs.
If I'm not able to travel, can I cancel my South Central Houston holiday package?
Yes, it's possible to cancel your South Central Houston booking if your travel plans have been upended. Whether you'll incur a penalty or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking free of charge if you booked in the last 24 hours. Head to our Customer Service Portal to find out more.
Stay near popular South Central Houston attractions
Photo by Michael Lore
University of Houston
8.2/10 (2,247 reviews)
Take a campus tour or just explore the area of University of Houston during your travels in Houston. Experience the great live music and lively festivals in this vibrant area.
Houston Zoo
8.6/10 (4,550 reviews)
Why not see the exotic and native animals who call Houston Zoo home during your holiday in Houston? Experience the area's fascinating museums and lively festivals.
Texas Southern University
10.0/10 (1 review)
Enjoy the student vibe when you visit Texas Southern University during your travels in Houston. Experience the acclaimed art galleries and lively festivals in this vibrant area.
Photo by Greater Houston Convention and Visitors Bureau (photographer: Hugh Hargrave)
Houston Museum of Fine Arts
9.4/10 (258 reviews)
You can spend time studying the exhibits at Houston Museum of Fine Arts during your trip to Houston. Experience the area's acclaimed theatre scene and fascinating museums.
Hermann Park
9.4/10 (13 reviews)
Hermann Park is just one of the places to see in Houston, so why not enjoy the other things to explore during your travels? Experience the area's lively festivals or attend a sporting event.
Photo by Mariam Ahmed
Children's Museum of Houston
8.8/10 (495 reviews)
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's acclaimed art galleries and great live music.
Houston Natural Science Museum
9.2/10 (1,036 reviews)
You can spend time browsing the exhibits at Houston Natural Science Museum during your trip to Houston. Experience the area's acclaimed theatre scene and great live music.
Main Street Theater - Rice Village
You can get tickets for a performance at Main Street Theater - Rice Village on your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.