The 10 Best 4 Star Hotels in Agathonisi - 2026 Updated Prices | Expedia

A coastal town with buildings on a hillside, a clear blue sea, and a boat anchored near the shore.

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Check availability on Agathonisi 4 Star Hotels

Tonight

14 Oct - 15 Oct

Tomorrow

15 Oct - 16 Oct

This weekend

16 Oct - 18 Oct

Next weekend

23 Oct - 25 Oct

Our top choices for Agathonisi 4-star hotels

A person in a colorful swimsuit standing on a balcony overlooking the ocean.

An indoor swimming pool with lounge chairs, a table, and a ceiling with wooden beams.

A coastal residential area with multi-story buildings, a swimming pool, and a view of the sea and a mountain in the distance.

A beach with clear blue water, a sandy shore, and a few boats. There are buildings with colorful roofs in the background.

1. Hydrele Beach Hotel

Samos

United States

armida

2.543.410 ₫

3.075.501 ₫ total

includes taxes & fees

15 Oct - 16 Oct

An outdoor cafe with tables, chairs, potted plants, and a tree with ripe oranges.

A spa area with a hot tub, two bean bag chairs, and several potted plants.

A modern kitchen with dark cabinetry, a central island, and two chairs.

A modern living room with a sofa, wooden side tables, a round ottoman, and a dining area with chairs and a kitchen in the background.

2. Doryssa Theorem Hotel

Samos

United States

Nicole

A pool area with lounge chairs and umbrellas, surrounded by stone walls and greenery.

A bedroom with a wooden wall, a hanging textured light fixture, and a bed with pillows.

A wooden deck with lounge chairs and a pool.

A boutique hotel entrance with a stone pathway, wooden gates, and potted plants.

3. Doryssa Boutique Hotel

Samos

Netherlands

Mika

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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Agathonisi.

Casa Cook Samos

Casa Cook Samos

Potokaki, Pythagorion Samos

5.951.369 ₫

6.953.294 ₫ total

28 Oct - 29 Oct

includes taxes & fees

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

Pythagorion Samos Samos Island

4.278.633 ₫

5.121.012 ₫ total

15 Oct - 16 Oct

includes taxes & fees

Doryssa Seaside Resort

Doryssa Seaside Resort

Pythagoreiou-Choras Samos Samos Island

4.577.893 ₫

5.450.172 ₫ total

15 Oct - 16 Oct

includes taxes & fees

8.8/10 Excellent! (183 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Agathonisi

Escape to this tranquil island where the pristine waters of Papa Beach invite swimming and snorkelling in crystal-clear seas. Explore the charming coves of Pálos and Spiliá, then wander to Vathý Pigádi where local fishermen bring in the day's catch.

See all hotels in Agathonisi

A coastal town with buildings on a hillside, a clear blue sea, and a boat anchored near the shore.

Top Agathonisi Hotel Reviews

Doryssa Boutique Hotel

Doryssa Boutique Hotel

10/10 Excellent

"The staff really make this hotel. Attentive, friendly and an absolute joy. Thank you for an amazing stay!"