Compare and book 4 Star hotels in Chillicothe, Missouri

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Check availability on Chillicothe 4 Star Hotels

Tonight
30 Nov - 1 Dec
Tomorrow
1 Dec - 2 Dec
Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec

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Chillicothe and related destinations

Nestled along the Wabash River, this family-friendly small town invites visitors to explore its charming Grayville Public Library and relax at Memorial Park. After enjoying local attractions, take a short drive to discover the intriguing Labyrinth State Memorial and artistic treasures at New Harmony Gallery of Contemporary Art.

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Illinois Central NO 8701 Old Illinois Passenger Depot Railroad Museum 121 S. Illinois Avenue Carbondale IL Photo taken on February 3, 2021

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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Chillicothe?
We can help you easily locate the perfect 4-star hotel for your trip to Chillicothe. Use our filter tool to tailor your search by things like budget, amenities and hotel star rating and get access to fantastic deals in a couple of clicks.

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What's the difference between 5-star and 4-star hotels in Chillicothe?
If you choose to spend your holiday at a 4-star hotel in Chillicothe, you'll typically find plenty of amenities to ensure you're comfortable, such as a gym, restaurant and pool. You can look forward to top-quality service and upscale accommodation. Go for a 5-star hotel and you'll have access to a few extra bells and whistles — think on-site spas, 24-hour front desk and nightly turndown services. You'll most likely get more amenities and first-class services at a 5-star retreat, though both are terrific options for luxury travellers.
Does Chillicothe have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your dream resort in Chillicothe where just about everything is taken care of, from your accommodation to your food, entertainment and activities. We can also help you find standard 4-star stays in and around this sought-after destination.

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