Compare and book 4 Star hotels in Florida Keys, United States of America

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys 4 Star Hotels

Our top choices for Florida Keys 4-star hotels

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very good, (1,007 reviews)
"Excellent place for family vacation "
United States
Aneesah
The price is 8.643.488 ₫
11.559.942 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Hawks Cay Resort

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,264 reviews)
"Beautiful grounds, very comfortable beds, provided water taxi between their 3 resorts, pool area with tiki bar very nice. "
United States
Judith
The price is 5.657.018 ₫
8.285.415 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Amara Cay Resort

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,004 reviews)
"Everything about this place was perfect, location, staff, comfort, and amenities. Can’t wait to go back!"
United States
Fabiane
The price is 8.918.819 ₫
11.482.047 ₫ total
includes taxes & fees
22 Jan - 23 Jan
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,003 reviews)
"Everything was great. Very clean and excellent location"
United States
peter
The price is 11.533.408 ₫
14.423.459 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Playa Largo Resort & Spa, Autograph Collection

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,249 reviews)
"Room was spotless, staff was so sweet and helpful when we had questions. Would stay here again !"
United States
Theresa
The price is 7.518.521 ₫
9.446.951 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,003 reviews)
"Rooms are clean, staff is friendly and the place is beautifull"
United States
James
The price is 8.407.040 ₫
11.231.280 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Islander Resort

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,003 reviews)
"Yes, the room was very clean. We especially enjoyed the heated small pool close to our room. The grounds were beautiful and very well maintained. We enjoyed the chairs by the water. "
United States
Hal
The price is 9.434.275 ₫
12.345.147 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Tranquility Bay Beachfront Hotel and Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,002 reviews)
"Great accommodations, very peaceful setting "
United States
Susan
The price is 8.139.722 ₫
11.078.459 ₫ total
includes taxes & fees
21 Jan - 22 Jan
La Siesta Resort & Villas

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon Shores
8.4 out of 10, Very good, (157 reviews)
"Love their mattress. Happy stay. Everything is convenient. Will come back."
United States
Kexin
Villas At Hawks Cay Resort

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (70 reviews)
"Amazing stay, can’t wait to stay there again!"
United States
Anonymous traveller
The price is 15.999.648 ₫
19.447.848 ₫ total
includes taxes & fees
19 Jan - 20 Jan
The Islands of Islamorada

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.0 star property
Marathon
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.4 out of 10, Exceptional, (8 reviews)
"The Reef was a great place to stay. The Villa was wonderful. The pool was great. Staff very friendly. I highly recommend this place. "
United States
Cynthia
The Reef at Marathon, Florida Keys

The Caribbean Resort Coconut Palm North

The Caribbean Resort Coconut Palm North
4.0 star property
Matecumbe
The Caribbean Resort Coconut Palm North
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Still don't see what you're looking for?
See all properties in Florida Keys.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Higgs Beach showing tropical scenes and a beach as well as a large group of people

Top Florida Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from 10.758.515 ₫

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.