A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Compare and book 4 Star hotels in Florida Keys, United States of America

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Check availability on Florida Keys 4 Star Hotels

Tonight
22 Oct - 23 Oct
Tomorrow
23 Oct - 24 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Florida Keys 4-star hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A poolside area with blue chairs and a thatched-roof structure.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A spacious bar area with high ceilings and large windows, offering views of the ocean.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Manny
5.664.654 ₫
7.407.505 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Reefhouse Resort & Marina
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.
A pathway leading to a pool area with palm trees and a sunset view.
A modern living room with a balcony overlooking the sea, furnished with a sofa, chairs, and a dining table.

2. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Antonio
5.635.943 ₫
8.707.176 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hawks Cay Resort
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
An aerial view of a resort with two large swimming pools surrounded by palm trees and lounge chairs.
Restaurant
A beachfront hotel with multiple balconies, a pool, and a beach area with lounge chairs.

3. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Alan
6.639.285 ₫
8.895.059 ₫ total
includes taxes & fees
29 Oct - 30 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A bar area with a wooden counter, bar stools, and potted plants.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.

4. Islander Resort

Islander Resort
Matecumbe
United States
Bryan
4.428.259 ₫
6.873.112 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Islander Resort
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A beach with palm trees, a dock, and lounge chairs.
A resort pool with palm trees, beach chairs, and umbrellas.
An aerial view of a resort with a swimming pool, palm trees, and a dock.

5. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Ronald
4.347.428 ₫
6.782.437 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Amara Cay Resort
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.
A beach with palm trees, a clear blue sky, and a calm sea.
A resort with a pool, beach, and ocean view.

6. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Liosbel
6.187.147 ₫
8.852.122 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
An aerial view of a resort with a large pool, palm trees, and a beach.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.

7. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Jorge
7.837.398 ₫
10.243.067 ₫ total
includes taxes & fees
9 Nov - 10 Nov
Playa Largo Resort & Spa, Autograph Collection
A swimming pool surrounded by palm trees and lounge chairs.
A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.
A beach scene with a wooden deck, palm trees, and a gazebo-like structure.
A spacious living room with a wooden coffee table, a striped sofa, and a television on a wooden cabinet.

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
5.359.435 ₫
7.689.961 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Tranquility Bay Beachfront Hotel and Resort
A bar area with a long counter, multiple stools, and a view of the marina with boats.
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a large tree in the background.
A fire pit with two Adirondack chairs and a table with drinks, set on a grassy area with a view of a building and palm trees in the background.
A living room with a grey sofa, a round coffee table, a wicker chair, and a flat-screen TV.

9. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United States
Rick
3.796.611 ₫
5.244.525 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A beach with colorful buildings, kayaks, and lounge chairs.
A beach resort with palm trees, a thatched hut, and a purple building with a window.
A row of colorful beach huts with palm trees in the background.

10. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
3.998.237 ₫
6.389.598 ₫ total
includes taxes & fees
15 Nov - 16 Nov
La Siesta Resort & Villas
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A bar area with stools, a counter, and hanging lanterns.
A beach with a wooden walkway leading to the water, palm trees, and a clear sky.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.

11. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
5.595.074 ₫
7.536.059 ₫ total
includes taxes & fees
12 Nov - 13 Nov
Grassy Flats Resort & Beach Club
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.
A modern kitchen with white cabinetry, a stainless steel oven, and a large island with a bowl of fruit.
An aerial view of a resort island with a large building, a swimming pool, and a boat docked nearby.

12. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Gabriela
12.001.824 ₫
15.102.640 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Villas At Hawks Cay Resort
A large hotel with a pool, multiple balconies, and palm trees.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.
A large, two-story hotel with a swimming pool in front.
A modern living room with a beige sectional sofa, large windows with wooden blinds, and a view of a marina and beach.

13. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
A resort with multiple buildings, a large central pool, and a view of the ocean.
A spacious dining area with a long table, wicker chairs, and hanging wicker lamps.
A poolside area with lounge chairs and palm trees.

14. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
Interior
A modern kitchen with white cabinets, a microwave, and a dishwasher. There are three bar stools and a large window overlooking the ocean.
A beach with clear turquoise water, a wooden pier, and a rocky shoreline.
A modern kitchen with white cabinetry, a built-in oven, and a large island with stools.

15. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
5.147.334 ₫
7.682.331 ₫ total
19 Nov - 20 Nov
includes taxes & fees
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
5.330.983 ₫
7.544.919 ₫ total
25 Oct - 26 Oct
includes taxes & fees
9.2/10 Wonderful! (1,295 reviews)
Isla Bella Beach Resort & Spa
The Islands of Islamorada

The Islands of Islamorada

82779 Old Hwy Islamorada FL
13.502.052 ₫
16.885.713 ₫ total
27 Oct - 28 Oct
includes taxes & fees
The Islands of Islamorada
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with a historic brick fort, a small seaplane, and a group of people walking along the shore.

Top Florida Keys Hotel Reviews

Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"Excellent"
Yusnier 1-night trip
Posted less than an hour ago
Amara Cay Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent
"Beautiful property, would stay there again"
Kathleen 2-night trip
Posted 1 hour ago
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"The hotel is expensive enough anyway without hidden extras Stealth tax what they’ve now labelled resort $50 a night tax plus $25 per night car parking Shame because it has a lovely vibe about the place"
Dean 1-night trip
Posted 1 day ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"The place is very relaxing. Very clean. No bugs. Helpful polite staff. No complains at all. Just keep the fact that additional charges at check out are quite high."
Frederick 5-night trip
Posted 2 days ago
Hawks Cay Resort

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from 7.544.919 ₫
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

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