A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

Compare and book 4 Star hotels in Jeffersonville, Louisville

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Jeffersonville 4 Star Hotels

Our top choices for Jeffersonville 4-star hotels

4 restaurants; breakfast, lunch and dinner served

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,192 reviews)
"Great hotel & stay!"
United States
Jennifer
The price is 4.104.712 ₫
4.829.604 ₫ total
includes taxes & fees
8 Aug - 9 Aug
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (2,017 reviews)
"Beautiful, clean property with many things to do at and around the hotel."
United States
Brittany
The price is 4.190.781 ₫
4.930.873 ₫ total
includes taxes & fees
2 Aug - 3 Aug
Omni Louisville Hotel
3 bars/lounges

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
Louisville
9.4 out of 10, Exceptional, (2,380 reviews)
"Great location friendly staff all around great place to stay"
United States
Zacarias
The price is 2.974.911 ₫
3.500.280 ₫ total
includes taxes & fees
28 Jul - 29 Jul
Derby City Gaming & Hotel - A Churchill Downs Property
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,006 reviews)
"Beautiful Hotel!"
United States
Joseph
The price is 3.137.821 ₫
3.691.961 ₫ total
includes taxes & fees
6 Aug - 7 Aug
Hyatt Regency Louisville
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,000 reviews)
"Beautiful property, on-site restaurant was delicious. Beds very nice."
United States
nicolle
The price is 4.005.197 ₫
4.844.135 ₫ total
includes taxes & fees
24 Aug - 25 Aug
21c Museum Hotel Louisville
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,280 reviews)
"Beautiful hotel!!!"
United States
Melanie
The price is 3.874.340 ₫
4.558.549 ₫ total
includes taxes & fees
28 Jul - 29 Jul
The Brown Hotel
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,010 reviews)
"Great place to stay!"
United States
Jennifer
The price is 4.294.574 ₫
5.052.995 ₫ total
includes taxes & fees
9 Aug - 10 Aug
The Grady
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,303 reviews)
"We liked everything about our stay"
United States
Mark
The price is 3.608.494 ₫
4.245.798 ₫ total
includes taxes & fees
16 Aug - 17 Aug
Embassy Suites Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location and friendly staff. Loved their bar and lobby area."
United States
Bikash
The price is 4.413.026 ₫
5.192.368 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Louisville Marriott Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,112 reviews)
"It was a nice place to stay with a fun vibe"
United States
Christina
The price is 3.552.525 ₫
4.179.900 ₫ total
includes taxes & fees
6 Aug - 7 Aug
Hotel Genevieve part of JdV by Hyatt
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (130 reviews)
"Great stay"
United States
Kristen
The price is 4.509.865 ₫
5.306.307 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (484 reviews)
"Great hotel and great staff."
United States
Jasmine
The price is 5.766.406 ₫
6.784.753 ₫ total
includes taxes & fees
9 Aug - 10 Aug
Hotel Distil, Autograph Collection
Front of property

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown
9.0 out of 10, Wonderful, (1,000 reviews)
"Nice clean hotel"
United States
Carrie
The price is 3.109.117 ₫
3.658.048 ₫ total
includes taxes & fees
9 Aug - 10 Aug
Marriott Louisville East
Exterior

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,001 reviews)
"Room was very clean."
United States
Whitney
The price is 4.333.554 ₫
5.098.860 ₫ total
includes taxes & fees
6 Aug - 7 Aug
Seelbach Hilton Louisville Downtown
Property entrance

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (714 reviews)
"Lovely property and excellent breakfast"
United States
Jacob
The price is 2.214.408 ₫
2.502.282 ₫ total
includes taxes & fees
26 Jul - 27 Jul
The Pepin Mansion Historic B&B
Lounge

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (143 reviews)
"Great location. Lots to do in the area. Room was clean and very nice."
United States
Brad
The price is 2.739.735 ₫
4.554.483 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Stellar Suites
Exterior

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (53 reviews)
"Nice place to stay"
United States
Chauntel
The price is 3.920.935 ₫
4.430.657 ₫ total
includes taxes & fees
1 Aug - 2 Aug
stayAPT Suites Louisville North-Clarksville
Seasonal outdoor pool

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.4 out of 10, Good, (34 reviews)
"Wonderful stay - great spot and lots of great dining options and bars nearby "
United States
Roy
The price is 1.815.735 ₫
5.161.950 ₫ total
includes taxes & fees
29 Jul - 30 Jul
CozySuites at Nulu
Front of property

Inn at St James Court

Inn at St James Court
4.0 star property
Old Louisville
9.8 out of 10, Exceptional, (134 reviews)
"The house is absolutely stunning! Pat the owner goes out of her way to make sure your stay is as wonderful as possible. She has everything for you toiletries, beverages, snacks, etc. She takes special orders for breakfast, which is amazing when traveling with picky eaters. "
United States
Anna
The price is 5.146.161 ₫
5.973.241 ₫ total
includes taxes & fees
31 Jul - 1 Aug
Inn at St James Court
32-inch Smart TV with cable channels

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (3 reviews)
"The room was great and clean. Great location. "
United States
De'Carlon
The Reserve on Main
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Jeffersonville.
Louisville Bourbon Inn

Louisville Bourbon Inn

1332 S 4th St Louisville KY
The price is 8.157.650 ₫ per night from 26 Jul to 27 Jul
8.157.650 ₫
9.468.584 ₫ total
26 Jul - 27 Jul
includes taxes & fees
10/10 Exceptional! (24 reviews)
Still don't see what you're looking for?
See all properties in Jeffersonville.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Jeffersonville

Stroll along the Ohio River on the revitalised RiverStage, where summer concerts happen with Louisville's skyline as backdrop. History buffs can explore the Howard Steamboat Museum, then grab a bite at one of the charming restaurants in the walkable city centre.

See all hotels in Jeffersonville
A bridge with colorful lights reflecting on the water at dusk.

Top Jeffersonville Hotel Reviews

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

10/10 Excellent
"Staff was nice everything was clean."
Jason 1-night trip
Posted 1 hour ago
Derby City Gaming & Hotel - A Churchill Downs Property

Frequently asked questions

What are the best 4-star hotels in Jeffersonville?
If you're seeking deluxe comfort and loads of amenities during your Jeffersonville getaway, check out Galt House Hotel Trademark Collection by Wyndham. This 4-star hotel comes with a swimming pool and beauty services. 21c Museum Hotel Louisville also gets excellent reviews from Expedia travellers. Spa facilities and treatment rooms are among its conveniences.
How much does it cost to stay in a 4-star hotel in Jeffersonville?
To find a 4-star hotel in Jeffersonville that's within your budget, take advantage of Expedia's handy filter tool. Check out the available options during your chosen dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly escape first.

  • Search for the lowest price from 9.468.584 ₫

What's the difference between 5-star and 4-star hotels in Jeffersonville?
If you choose to stay at a 4-star hotel in Jeffersonville, you'll usually find loads of conveniences to keep you comfortable, such as a gym, restaurant and pool. You can look forward to top-quality service and upmarket accommodation. Pick a 5-star hotel and you'll have access to a few extra perks — think around-the-clock concierge, on-site spas and indulgent turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury travellers.