A paved pathway lined with tropical plants and palm trees, leading to a gazebo and a fountain.

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Check availability on Sanibel 4 Star Hotels

Tonight
7 Sep - 8 Sep
Tomorrow
8 Sep - 9 Sep
This weekend
11 Sep - 13 Sep
Next weekend
18 Sep - 20 Sep

Our top choices for Sanibel 4-star hotels

A spacious living room with a grey sofa, striped armchair, and a woven coffee table. Large windows offer a view of a tropical garden.
A bedroom with a bed, nightstands, a ceiling fan, a window with a view of greenery, and a sliding glass door.
A garden with a thatched-roof structure, palm trees, and a gravel path.
A modern living room with a sofa, a coffee table, and a dining area with a table and chairs.

1. Driftwood Inn

Driftwood Inn
Mid Island
United States
Maureen
5.633.280 ₫
12.580.730 ₫ total
includes taxes & fees
8 Sept - 9 Sept
Driftwood Inn
A spacious bedroom with a large bed, a ceiling fan, a view of the outdoors, and a seating area with a chair and ottoman.
A two-story building with a white exterior, a balcony on the upper floor, and a door with a glass panel.
A modern kitchen with stainless steel appliances, white cabinetry, and a built-in microwave.
A hotel room with two single beds, a ceiling fan, and a window with patterned curtains.

2. Lighthouse Resort and Club

Lighthouse Resort and Club
East End
Lighthouse Resort and Club
A wooden boardwalk leading to a beach with palm trees and a clear view of the ocean.
A spacious living area with a blue sofa, a wooden coffee table, and a dining table with chairs. A kitchen is visible in the background.
A modern living room with a sofa, chairs, a dining table, and a kitchen area.
A resort with multiple white buildings, a swimming pool, and a view of the ocean.

3. Shell Island Beach Club

Shell Island Beach Club
East End
United States
Nancy
Shell Island Beach Club
A resort with multiple buildings, a swimming pool, and a view of the ocean.
A modern kitchen with wooden cabinets, a stainless steel microwave, a built-in oven, a sink, and pendant lighting.
A living room with a sofa, a coffee table, and a dining area with chairs and a table.
A modern kitchen with a granite countertop, wooden cabinets, and a large island with a sink. There is a dining area with a table and chairs, and a balcony with a view.

4. Blue Gulf 201

Blue Gulf 201
West End
Blue Gulf 201
A spacious living room with a large green sofa, a ceiling fan, and a view of the ocean through large windows.
A modern kitchen with white cabinets, stainless steel appliances, and a marble countertop.
A spacious living room with a blue sofa, a coffee table, and a dining area with white chairs.
A hotel with a pool, multiple balconies, and palm trees.

5. Surfside 12 C4

Surfside 12 C4
East End
Surfside 12 C4
A spacious living room with a large sliding glass door leading to a balcony overlooking the ocean.
A balcony with a view of the beach and ocean.
A coastal resort with beachfront properties, a central building complex, and surrounding greenery.
A modern kitchen with granite countertops, stainless steel appliances, and a breakfast bar with wicker chairs.

6. Shorewood Condos by Dream Vacation Rentals

Shorewood Condos by Dream Vacation Rentals
Mid Island
Shorewood Condos by Dream Vacation Rentals
A resort with a swimming pool, a beach, and a view of the ocean.
An aerial view of a resort with multiple buildings, a swimming pool, and lush greenery.
A balcony with a view of a pool and palm trees, a wicker sofa, and a round wicker table.
A modern kitchen with a central island, bar stools, and a ceiling fan.

7. Sand Pointe 212

Sand Pointe 212
West End
Sand Pointe 212

8. Pointe Santo Condos by Dream Vacation Rentals

Pointe Santo Condos by Dream Vacation Rentals
Mid Island
Pointe Santo Condos by Dream Vacation Rentals
A resort with a central swimming pool, multiple buildings with balconies, and a view of the beach and ocean.
A living room with a TV, a sofa, a chair, a coffee table, and a lamp. There is a sliding glass door leading to a balcony with a view of trees.
A modern living room with a large window, a ceiling fan, a flat-screen TV, and a sofa with patterned cushions.
A well-maintained grassy area with palm trees, a pathway, and a view of the ocean.

9. Loggerhead Cay by Dream Vacation Rentals

Loggerhead Cay by Dream Vacation Rentals
Mid Island
Loggerhead Cay by Dream Vacation Rentals

10. Breakers West B5

Breakers West B5
West End
Breakers West B5
An aerial view of a coastal resort with beachfront villas, a swimming pool, and a road running parallel to the beach.
A modern living room with a leather sofa, a flat-screen TV, a coffee table, and a dining area with chairs and a glass door leading to a balcony.
A kitchen with a granite countertop, wooden chairs, a microwave, and a refrigerator.
A bedroom with a bed, bedside tables, a bench, a dresser, a mirror, and a television.

11. Villa Sanibel 2B

Villa Sanibel 2B
Mid Island
Villa Sanibel 2B
A swimming pool with a white fence, two umbrellas, and lounge chairs.
A bedroom with a bed, two bedside tables with lamps, a ceiling fan, a window with curtains, and a view of the ocean.
A resort with multiple buildings, a central pool, and a beach view.
A pathway leading to a residential area with modern buildings, a landscaped garden, and a clear blue sky.

12. Sanibel Beach Club 2

Sanibel Beach Club 2
East End
Sanibel Beach Club 2
A spacious living room with a beige sofa, a grey armchair, and a dining area with white chairs. A ceiling fan and a TV are mounted on the wall.
A bedroom with a bed, a ceiling fan, a window, and a starfish decoration.
A living room with a sofa, armchair, coffee table, and lamps. There is a painting on the wall and a window with curtains.
A dining area with a round wooden table, white chairs, and a chandelier.

13. Spanish Cay by Dream Vacation Rentals

Spanish Cay by Dream Vacation Rentals
Mid Island
Spanish Cay by Dream Vacation Rentals
A spacious living room with a sofa, chairs, a coffee table, and a TV. There are large windows and a ceiling fan.
A well-maintained backyard with a lawn, various plants, a small shed, and a greenhouse structure.
A single-story house with a porch, surrounded by tropical vegetation.
A covered swimming pool with a sunshade, lounge chairs, and a patio area with outdoor furniture.

14. Coconut Palms

Coconut Palms
Mid Island
Coconut Palms

15. Compass Point 122

Compass Point 122
Mid Island
Compass Point 122
A balcony with glass doors, a small table, two chairs, and a potted plant.
A living room with a sofa, armchair, and a dining table. There is a ceiling fan, a cabinet, and a blue door.
A residential area with houses near a calm lake, surrounded by greenery and palm trees.
A modern two-story house with a covered porch, surrounded by lush greenery and palm trees.

16. A Peace of Heaven

A Peace of Heaven
Mid Island
A Peace of Heaven
A modern kitchen with a granite island, stainless steel appliances, and white cabinetry.
A modern kitchen with granite countertops, stainless steel appliances, and a large island.
A swimming pool with a tiled deck, surrounded by a white fence and trees in the background.
A house with a blue roof, surrounded by lush tropical vegetation and a well-maintained lawn.

17. Twin Lakes Home

Twin Lakes Home
West End
Twin Lakes Home

18. Pointe Santo Condos by Dream Vacation Rentals

Pointe Santo Condos by Dream Vacation Rentals
Mid Island
Pointe Santo Condos by Dream Vacation Rentals

19. D1 2bed/2bath

D1 2bed/2bath
East End
D1 2bed/2bath

20. Chip Shot

Chip Shot
Mid Island
Chip Shot
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Sanibel.
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL
8.845.032 ₫
11.577.884 ₫ total
8 Sept - 9 Sept
includes taxes & fees
8.6/10 Excellent! (2,696 reviews)
Sundial Beach Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Sanibel

Shell-seekers flock to pristine beaches where the 'Sanibel Stoop' is the local posture for finding perfect specimens. Bike the 25-mile trail network through wildlife refuges where alligators sunbathe and over 245 bird species can be spotted with binoculars.

See all hotels in Sanibel
A lighthouse with a glass lantern room, surrounded by palm trees and a sunset sky.

Top Sanibel Hotel Reviews

Driftwood Inn

Driftwood Inn

10/10 Excellent
"The cottage was well stocked with all we needed. It was also immaculate with a lovely garden. The beach was a 5 minute walk."
Maureen 3-night trip
Posted 3 months ago
Driftwood Inn

Frequently asked questions

What are the best 4-star hotels in Sanibel?
If you're searching for high-quality comfort and loads of amenities on your Sanibel getaway, check in to Marriott Sanibel Harbour Resort & Spa. This leading 4-star hotel offers a spa tub and spa facilities. Pink Shell Beach Resort and Marina also gets rave reviews from Expedia customers. Beauty services and a resort are among its conveniences.
How much does it cost to stay in a 4-star hotel in Sanibel?
To book a 4-star hotel in Sanibel that's within your budget, use Expedia's sort and search filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also list your results by the cheapest property first.
  • Search for the lowest price from 11.577.884 ₫
What's the difference between 5-star and 4-star hotels in Sanibel?
Treat yourself to luxury during your Sanibel escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are usually filled with amenities like large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and unforgettable one. Round-the-clock concierge assistance, elegant furnishings and gourmet dining are only the start of the first-rate conveniences and services you'll likely get access to.

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