Default HTG hotel image

Compare and book 4 Star hotels in Southwest Houston, Houston

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Houston 4 Star Hotels

Our top choices for Southwest Houston 4-star hotels

Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very good, (2,040 reviews)
"Great place to stay at super clean and nice area and everything was nearby"
United States
Marvin
The price is 2.462.873 ₫
2.912.098 ₫ total
includes taxes & fees
1 Aug - 2 Aug
Hilton Houston Plaza/Medical Center
Lobby

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,856 reviews)
"Excellent staff, service and amenities. Everything was great, highly recommend staying here!"
Canada
Feroze
The price is 3.862.516 ₫
4.519.144 ₫ total
includes taxes & fees
7 Aug - 8 Aug
Blossom Hotel Houston, Curio Collection by Hilton
Exterior

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
Greater Uptown
8.4 out of 10, Very good, (4,298 reviews)
"Great place to stay"
United States
Michael
The price is 3.000.410 ₫
3.535.225 ₫ total
includes taxes & fees
1 Aug - 2 Aug
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Presidential Suite, 1 King Bed | Premium bedding, in-room safe, desk, iron/ironing board

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
Greenway Plaza-Upper Kirby
8.4 out of 10, Very good, (1,744 reviews)
"Excellent place to stay with family"
United States
Fahad
The price is 2.136.252 ₫
2.499.414 ₫ total
includes taxes & fees
7 Aug - 8 Aug
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Lounge

The Westin Galleria Houston

The Westin Galleria Houston
4.5 star property
The Galleria
9.2 out of 10, Wonderful, (1,005 reviews)
"Great place to stay"
United States
David
The price is 4.610.388 ₫
6.229.929 ₫ total
includes taxes & fees
7 Aug - 8 Aug
The Westin Galleria Houston
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,420 reviews)
"Awesome location and amenities. Great hotel!"
United States
Zahra
The price is 4.001.248 ₫
4.711.996 ₫ total
includes taxes & fees
8 Aug - 9 Aug
Hyatt Regency Houston/Galleria
3 bars/lounges, lobby lounge

Omni Houston Hotel

Omni Houston Hotel
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,005 reviews)
"Staff was great, room was clean, amazing stay"
United States
Antonio
The price is 4.447.498 ₫
5.281.623 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Omni Houston Hotel
Outdoor pool, free pool cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,167 reviews)
"Nice and convenient for our stay"
United States
Darrell
The price is 4.239.347 ₫
5.276.715 ₫ total
includes taxes & fees
31 Jul - 1 Aug
The Westin Houston Medical Center/Museum District
Outdoor pool, open 6:00 AM to 10:00 PM, pool loungers

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (1,006 reviews)
"Was a great place to stay very close to MD Anderson"
United States
Heather
The price is 3.733.046 ₫
4.894.064 ₫ total
includes taxes & fees
21 Aug - 22 Aug
InterContinental Houston by IHG
Breakfast, lunch and dinner served

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center
8.4 out of 10, Very good, (637 reviews)
"Good location for the medical center, and decent rates. The breakfast was very good."
United States
John
The price is 3.215.167 ₫
3.761.745 ₫ total
includes taxes & fees
1 Aug - 2 Aug
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Serves dinner and happy hour

The Chifley Houston, Tapestry Collection by Hilton

The Chifley Houston, Tapestry Collection by Hilton
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,318 reviews)
"Clean room, nice staff, good location."
United States
Adam
The price is 2.999.384 ₫
3.509.279 ₫ total
includes taxes & fees
7 Aug - 8 Aug
The Chifley Houston, Tapestry Collection by Hilton
Staircase

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria
8.6 out of 10, Excellent, (2,135 reviews)
"The property is really nice and the staff is really friendly"
United States
Fransheska
The price is 3.789.360 ₫
4.433.551 ₫ total
includes taxes & fees
7 Aug - 8 Aug
The Royal Sonesta Houston Galleria
Exterior

Houston Marriott Uptown by the Galleria

Houston Marriott Uptown by the Galleria
4.0 star property
The Galleria
8.0 out of 10, Very good, (922 reviews)
"Everything was clean and the entire staff was amazing!"
United States
Raen
The price is 3.136.748 ₫
3.730.615 ₫ total
includes taxes & fees
1 Aug - 2 Aug
Houston Marriott Uptown by the Galleria
Dinner served

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (1,002 reviews)
"I enjoyed my stay!"
United States
Valencia
The price is 4.002.512 ₫
5.525.550 ₫ total
includes taxes & fees
31 Jul - 1 Aug
Houston Marriott Medical Center/Museum District
Exterior

JW Marriott Houston by the Galleria

JW Marriott Houston by the Galleria
4.5 star property
The Galleria
8.8 out of 10, Excellent, (1,001 reviews)
"Well located with connecting rooms available. "
United States
Raul
The price is 5.660.357 ₫
7.446.540 ₫ total
includes taxes & fees
1 Aug - 2 Aug
JW Marriott Houston by the Galleria
55-inch flat-screen TV with cable channels, Smart TV, pay films

The Westin Oaks Houston at the Galleria

The Westin Oaks Houston at the Galleria
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,002 reviews)
"The staff was friendly and the rooms were in tip top shape. No complaints"
United States
Matthew
The price is 4.610.388 ₫
6.229.929 ₫ total
includes taxes & fees
7 Aug - 8 Aug
The Westin Oaks Houston at the Galleria
Lobby

Hilton Houston Post Oak by the Galleria

Hilton Houston Post Oak by the Galleria
4.0 star property
The Galleria
8.2 out of 10, Very good, (1,002 reviews)
"Great stay"
United States
James
The price is 3.216.266 ₫
3.763.031 ₫ total
includes taxes & fees
2 Aug - 3 Aug
Hilton Houston Post Oak by the Galleria
Library

Hotel Granduca Houston

Hotel Granduca Houston
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,003 reviews)
"Always a great hotel! Rooms are great. Staff is helpful and kind. Love it"
United States
london
The price is 6.505.068 ₫
7.662.970 ₫ total
includes taxes & fees
16 Aug - 17 Aug
Hotel Granduca Houston
Breakfast area

The Greenleigh, River Oaks, Autograph Collection

The Greenleigh, River Oaks, Autograph Collection
4.0 star property
The Galleria
5.8 out of 10, (1,000 reviews)
"I always have a wonderful stay here"
United States
Kalyn
The Greenleigh, River Oaks, Autograph Collection
Dining room

Cozy Retreat Near NRG Stadium, Free parking, Wi Fi

Cozy Retreat Near NRG Stadium, Free parking, Wi Fi
4.0 star property
Southeast Houston
10.0 out of 10, Exceptional, (1 review)
"Highly recommended!"
United States
Jayson
Cozy Retreat Near NRG Stadium, Free parking, Wi Fi
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Southwest Houston.
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

1600 West Loop South Houston TX
The price is 15.157.440 ₫ per night from 12 Aug to 13 Aug
15.157.440 ₫
17.734.206 ₫ total
12 Aug - 13 Aug
includes taxes & fees
Still don't see what you're looking for?
See all properties in Southwest Houston.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southwest Houston

Gourmet restaurants, beloved sports teams and top sights from NRG Stadium to NRG Park—discover Southwest Houston, a destination also famous for its shopping.

See all hotels in Southwest Houston
A water feature with a cascading waterfall, a grassy hill, and a tall building in the background.
Photo by George Zimzores
Open Photo by George Zimzores

Top Southwest Houston Hotel Reviews

Omni Houston Hotel

Omni Houston Hotel

10/10 Excellent
"pool was great but not alot of shade"
Marilena 2-night trip
Posted 5 hours ago
Omni Houston Hotel

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Southwest Houston?
With Expedia's handy filter tool, locking in a superb deal on a 4-star hotel in Southwest Houston just got easier. Start by entering your chosen arrival date and length of your stay. Then sort the results by price and pick a hotel that best suits your style and budget.

  • Search for the lowest price from 6.254.693 ₫

What's the difference between 5-star and 4-star hotels in Southwest Houston?
Give yourself the luxury treatment during your Southwest Houston holiday by staying at a 4-star hotel. As well as featuring upmarket accommodation, these properties are usually filled with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and special one. 24-hour concierge assistance, elegant décor and gourmet dining are only the start of the superior services and conveniences you'll likely get access to.
Does Southwest Houston have any 4-star all-inclusive resorts?
Enjoy a worry-free holiday experience where almost everything is included in the one upfront rate by using our "All inclusive" filter. Staying within budget is a piece of cake when your room, meals and many activities are already taken care of. Eager for more ideas? Browse the incredible offers on Expedia's standard 4-star hotels in and around Southwest Houston too.