Compare and book 4 Star hotels in Wapello, Iowa

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Check availability on Wapello 4 Star Hotels

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Wapello 4 Star Hotels

Breakfast, lunch, dinner served; American cuisine
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

4.0 star property
Muscatine
9.6 out of 10, Exceptional, (277)
"Great Hotel. The restaurant, Maxwell's was very good."
United States
Dennis
The price is 4.684.453 ₫
5.246.587 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Front of property
Evans Holly Grove Inn B&B

Evans Holly Grove Inn B&B

4.0 star property
Burlington
9.6 out of 10, Exceptional, (195)
"Delicious breakfast!!!"
United States
Geremy
The price is 3.441.154 ₫
3.854.092 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Evans Holly Grove Inn B&B
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Learn more about Wapello

Along the banks of the mighty Mississippi, this charming river town invites visitors to explore Chatauqua Park's natural beauty and peaceful surroundings. History buffs and outdoor enthusiasts can venture to nearby Lover's Leap Swinging Bridge or spend an exciting evening watching local races at CJ Speedway.

See all hotels in Wapello
The Mississippi River near Hannibal, Missouri, USA

Top Wapello Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Wapello?
To book a 4-star hotel in Wapello that matches your budget, use Expedia's search and sort filters. Take a look at the available options during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly retreat first.

  • Search for the lowest price from 3.854.092 ₫

What's the difference between 5-star and 4-star hotels in Wapello?
Treat yourself to refined living during your Wapello escape by staying at a 4-star hotel. As well as featuring upscale accommodation, these properties are usually packed with amenities, including bathrobes, large beds and plenty more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and memorable one. Concierge assistance, on-site spas and gourmet dining are a few of the superior services and conveniences you'll likely get access to.
Does Wapello have any 4-star all-inclusive resorts?
Finding your dream hotel in Wapello is as simple as entering your dates and destination, and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodation, food, activities and entertainment, or go for a standard 4-star resort in or around this leading destination.

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