Compare and book 5 Star hotels in Big Pine Key, Florida
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Big Pine Key 5 Star Hotels
Tonight
19 Aug - 20 AugTomorrow
20 Aug - 21 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Big Pine Key 5-star hotels
5.866.490 ₫
8.182.000 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.
Tranquility Bay Beachfront Hotel and Resort
2600 Overseas Hwy Marathon FL
5.424.082 ₫
7.782.720 ₫ total
13 Sept - 14 Sept
includes taxes & fees
8.8/10 Excellent! (1,007 reviews)
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
1996 Overseas Highway Marathon FL
3.842.554 ₫
5.307.990 ₫ total
20 Sept - 21 Sept
includes taxes & fees
Grassy Flats Resort & Beach Club
58182 Overseas Hwy Marathon FL
3.777.264 ₫
5.506.013 ₫ total
20 Sept - 21 Sept
includes taxes & fees
9.4/10 Exceptional! (486 reviews)
Still don't see what you're looking for?
See all properties in Big Pine Key.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Big Pine Key
Snorkel crystal-clear waters teeming with colourful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.
See all hotels in Big Pine Key
Top Big Pine Key Hotel Reviews
Frequently asked questions
How much does it cost to stay in a 5-star hotel in Big Pine Key?
How much you pay for a 5-star hotel in Big Pine Key depends on factors like when you want to go and the length of your escape. An insider tip for bagging an awesome deal? Use our pricing filters to compare the available options for your preferred dates.
- Search for the lowest price per night from 5.307.990 ₫
What makes a hotel 5 stars in Big Pine Key?
From fine dining venues and 24/7 fitness centres to pools and luxury bedding, the 5-star experience in Big Pine Key is all about luxury and relaxation. But it takes more than just top-notch amenities to get a 5-star rating. Accommodation also have to offer extraordinary guest-centric services like in-room beauty treatments, laundry and dry cleaning and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Big Pine Key?
Use our handy filters to find a luxury escape in Big Pine Key where most of what you need is included in the price. After your initial search, refine your results for accommodation that have a 5-star rating and are categorised as "All inclusive." The first thing on the schedule at these stays? Pure relaxation and indulgence.