Compare and book 5 Star hotels in Central United States, United States of America

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central United States 5 Star Hotels

Tonight
2 Dec - 3 Dec
Tomorrow
3 Dec - 4 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Central United States 5 Star Hotels

Reception
The Roosevelt New Orleans, A Waldorf Astoria Hotel

The Roosevelt New Orleans, A Waldorf Astoria Hotel

5.0 star property
New Orleans Central Business District
9.2 out of 10, Wonderful, (1018)
"We found our stay here to be very enjoyable."
United States
Lesley
The price is 5.070.231 ₫
5.972.233 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Roosevelt New Orleans, A Waldorf Astoria Hotel
Reception
Four Seasons Hotel Chicago

Four Seasons Hotel Chicago

5.0 star property
Downtown Chicago
9.4 out of 10, Exceptional, (1006)
"Amazing hotel"
United States
David
The price is 11.074.980 ₫
13.000.920 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Four Seasons Hotel Chicago
Lobby
The Langham, Chicago

The Langham, Chicago

5.0 star property
Downtown Chicago
9.8 out of 10, Exceptional, (1009)
"Langham is always a superior stay"
United States
THADDEUS LAMONT
The price is 12.732.272 ₫
14.946.415 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Langham, Chicago
Front of property – evening/night
The Peninsula Chicago

The Peninsula Chicago

5.0 star property
Downtown Chicago
9.8 out of 10, Exceptional, (1022)
"Great rooms, location and top flight service"
United States
Andrew
The price is 13.336.649 ₫
15.655.803 ₫ total
includes taxes & fees
8 Dec - 9 Dec
The Peninsula Chicago
Front of property
The Windsor Court

The Windsor Court

5.0 star property
New Orleans Central Business District
9.8 out of 10, Exceptional, (1007)
"Wonderful stay with my family. Great staff and very clean."
United States
Jonathan
The price is 10.546.000 ₫
12.365.185 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
The Windsor Court
Bar (on property)
Trump International Hotel & Tower Chicago

Trump International Hotel & Tower Chicago

5.0 star property
Downtown Chicago
9.4 out of 10, Exceptional, (1783)
"Great stay "
United States
Mohammed
The price is 9.135.472 ₫
10.724.128 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Trump International Hotel & Tower Chicago
Seasonal outdoor pool, pool cabanas (surcharge), pool umbrellas
Thompson Dallas, by Hyatt

Thompson Dallas, by Hyatt

5.0 star property
Downtown Dallas
9.0 out of 10, Wonderful, (479)
"The staff does a truly exceptional job at ensuring their guests are happy. I highly recommend! They always go above and beyond. "
United States
JEFF
The price is 6.940.321 ₫
9.143.698 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Thompson Dallas, by Hyatt
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

5.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (912)
"Outstanding hotel "
United States
Hicham
The price is 4.722.688 ₫
6.479.841 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Thompson San Antonio - Riverwalk, by Hyatt
Outdoor pool, pool cabanas (surcharge), pool umbrellas
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

5.0 star property
The Galleria
9.6 out of 10, Exceptional, (878)
"Beautiful hotel "
United States
nabintou
The price is 13.894.355 ₫
16.256.397 ₫ total
includes taxes & fees
25 Dec - 26 Dec
The Post Oak Hotel at Uptown Houston
Exterior
Hotel Crescent Court

Hotel Crescent Court

5.0 star property
Uptown
9.2 out of 10, Wonderful, (1008)
"Quiet, beautiful, and well appointed rooms. "
United States
Jill
The price is 8.067.690 ₫
11.332.926 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hotel Crescent Court
Outdoor pool, open 7:00 AM to 8:00 PM, pool cabanas (surcharge)
The Joseph, a Luxury Collection Hotel, Nashville

The Joseph, a Luxury Collection Hotel, Nashville

5.0 star property
Downtown Nashville
9.4 out of 10, Exceptional, (442)
"Great Hotel , front desk staff were amazing, we will be back !"
Canada
Jackie
The price is 5.693.067 ₫
7.851.720 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Joseph, a Luxury Collection Hotel, Nashville
Exterior
Conrad Nashville

Conrad Nashville

5.0 star property
Downtown Nashville
9.6 out of 10, Exceptional, (1060)
"good hotel and location"
United States
James
The price is 5.816.474 ₫
6.856.655 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Conrad Nashville
Exterior
Waldorf Astoria Chicago

Waldorf Astoria Chicago

5.0 star property
Downtown Chicago
9.4 out of 10, Exceptional, (1008)
"The staff was amazing. Will be making a return stay."
United States
Patricia
The price is 10.018.700 ₫
11.760.952 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Waldorf Astoria Chicago
Exterior
The Joule

The Joule

5.0 star property
Downtown Dallas
9.2 out of 10, Wonderful, (1010)
"Beautiful excellent service, hotel, food, style. "
Canada
Smar
The price is 7.333.219 ₫
9.684.577 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Joule
Interior entrance
Rosewood Mansion on Turtle Creek

Rosewood Mansion on Turtle Creek

5.0 star property
Oak Lawn
9.4 out of 10, Exceptional, (771)
"Amazing stay and service!"
United States
Mike
The price is 14.134.804 ₫
18.031.287 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Rosewood Mansion on Turtle Creek
Terrace/patio
1 Hotel Nashville

1 Hotel Nashville

5.0 star property
Downtown Nashville
9.4 out of 10, Exceptional, (946)
"Our stay at 1 hotel one was a great experience"
United States
Marcela
The price is 6.225.792 ₫
8.258.091 ₫ total
includes taxes & fees
28 Dec - 29 Dec
1 Hotel Nashville
Suite, Terrace (Water Tower) | Premium bedding, down duvets, pillow-top beds, minibar
Park Hyatt Chicago

Park Hyatt Chicago

5.0 star property
Downtown Chicago
9.6 out of 10, Exceptional, (1002)
"Stay was amazing!!! The staff was so friendly, kind, and thoughtful! The rooms were soooo beyond perfect and lovely! And the food at the restaurant was amazing.. especially breakfast! You won’t regret staying here!!! "
United States
Larissa
The price is 11.468.775 ₫
13.463.193 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Park Hyatt Chicago
Bar (on property)
Four Seasons Hotel New Orleans

Four Seasons Hotel New Orleans

5.0 star property
New Orleans Central Business District
9.6 out of 10, Exceptional, (591)
"Great service, early check-in, birthday and holiday amenity was nice touch. "
United States
Matthew
The price is 10.547.600 ₫
12.367.061 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Four Seasons Hotel New Orleans
Banquet hall
JW Marriott Nashville

JW Marriott Nashville

5.0 star property
Downtown Nashville
9.2 out of 10, Wonderful, (1010)
"Fantastic hotel. Great location and service Definitely recommend and will be back "
United States
Phillip
The price is 5.805.135 ₫
7.766.332 ₫ total
includes taxes & fees
22 Dec - 23 Dec
JW Marriott Nashville
Exterior
The Loren Hotel Austin

The Loren Hotel Austin

5.0 star property
Zilker
9.4 out of 10, Exceptional, (339)
"High quality amenities, great service at Nido, beautiful property."
United States
Ebony
The price is 6.668.357 ₫
8.960.040 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Loren Hotel Austin
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central United States.
Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

2800 Opryland Drive Nashville TN
The price is 8.270.637 ₫ per night from 16 Dec to 17 Dec
8.270.637 ₫
10.645.333 ₫ total
16 Dec - 17 Dec
includes taxes & fees
8.6/10 Excellent! (1,741 reviews)
Still don't see what you're looking for?
See all properties in Central United States.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Central United States

Enjoy access to sights and activities in the surrounding area during your stay in Central United States.

See all hotels in Central United States
Downtown Nashville which includes a city, a sunset and boating

Top Central United States Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Central United States?
The Knickerbocker Hotel is a top pick for Expedia customers. The Chatwal, In The Unbound Collection By Hyatt and InterContinental New York Times Square, an IHG Hotel also get rave reviews from travellers. All located in New York, Central United States, these 5-star hotels will treat you to a life of luxury from the moment you enter the lobby.
How much does it cost to stay in a 5-star hotel in Central United States?
There are several pricing options for 5-star hotels in Central United States on Expedia. The amount you pay will depend on when you plan to travel, length of stay and other factors. Compare available properties for your chosen dates and use our pricing and other filters to find the perfect high-end stay.

  • Search for the lowest price per night from 2.919.016 ₫

What makes a hotel 5 stars in Central United States?
From gourmet restaurants and 24-hour gyms to pools and premium bedding, the 5-star experience in Central United States is all about luxury and relaxation. But it takes more than just upscale conveniences to earn a 5-star rating. Accommodation must also offer outstanding services like massage treatments, on-site laundry and 24-hour room service.

Explore a world of travel with Expedia