Compare and book 5 Star hotels in Hyannis, Massachusetts

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Check availability on Hyannis 5 Star Hotels

Tonight
28 Jun - 29 Jun
Tomorrow
29 Jun - 30 Jun
Next weekend
4 Jul - 6 Jul
In two weeks
11 Jul - 13 Jul

Top Hyannis 5 Star Hotels

Chatham Bars Inn
Seasonal outdoor pool

Chatham Bars Inn

5.0 star property
9.2 out of 10, Wonderful, (769)
"The atmosphere and views are breathtaking. The staff was extremely cordial and doted over us while we celebrated our 50th anniversary. "
The price is 20.484.575 ₫
24.616.826 ₫ total
includes taxes & fees
23 Jul - 24 Jul
Chatham Bars Inn
Wequassett Resort and Golf Club
6 restaurants, breakfast, lunch, dinner served; American cuisine

Wequassett Resort and Golf Club

5.0 star property
9.4 out of 10, Exceptional, (225)
"An absolute delight, had a wonderful stay, can’t wait to return"
Wequassett Resort and Golf Club
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Hyannis.
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

1225 Iyannough Rd, Hyannis, MA
The price is 14.848.055 ₫ per night from 5 Jul to 6 Jul
14.848.055 ₫
18.487.003 ₫ total
5 Jul - 6 Jul
includes taxes & fees
8.6/10 Excellent! (196 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Hyannis

Stroll the bustling harbour and hop aboard a ferry to Martha's Vineyard or Nantucket for a day trip. Visit the John F. Kennedy Hyannis Museum to learn about the president's connection to Cape Cod's summer playground.

See all hotels in Hyannis
Hyannis featuring a bay or harbour and a marina

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Hyannis?
You'll find many different pricing options for 5-star hotels in Hyannis on Expedia. How much you'll pay will depend on when you travel, trip length and other factors. Compare available properties for your desired dates and make use of our pricing and other filters to lock in the perfect luxury stay.

  • Search for the lowest price per night from 6.410.237 ₫

What makes a hotel 5 stars in Hyannis?
Exceptional guest service is integral to every 5-star hotel in Hyannis. From the moment you arrive, staff cater to your every need, whether recommending activities or providing in-room beauty treatments. In addition, hotels must feature top-rate amenities to meet the standard for a 5-star rating. These can include luxury toiletries, on-site spa facilities, swimming pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Hyannis?
Use our filter tool to find a high-end getaway in Hyannis where most of what you need is included. After your initial search, refine your results for properties that have a rating of 5 stars and are described as "All inclusive." The most important thing on the agenda at these stays? Pure enjoyment and indulgence.