A cobblestone street leading up to a historic town with stone buildings and a green fence.

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Check availability on Irsina 5 Star Hotels

This weekend
10 Jul - 12 Jul
Next weekend
17 Jul - 19 Jul

Our top choices for Irsina 5-star hotels

Premium bedding, minibar, in-room safe, individually decorated

Aquatio Cave Luxury Hotel & SPA

Aquatio Cave Luxury Hotel & SPA
5.0 star property
Matera
9.6 out of 10, Exceptional, (600 reviews)
"Beautiful hotel with very attentive and nice staff"
United States
Michael
The price is 7.274.427 ₫
8.241.806 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Aquatio Cave Luxury Hotel & SPA
Couples treatment room(s), Turkish bath/hammam, body treatments

Palazzo Gattini Luxury Hotel

Palazzo Gattini Luxury Hotel
5.0 star property
Matera
9.6 out of 10, Exceptional, (219 reviews)
"Staff was extremely helpful, always available, very pleasant to deal with at all times. Amenities were fantastic. Would definitely stay here again."
Canada
Elaine
The price is 8.244.805 ₫
9.309.222 ₫ total
includes taxes & fees
2 Aug - 3 Aug
Palazzo Gattini Luxury Hotel
Daily buffet breakfast for a fee

Eurostars Matera LaSuite

Eurostars Matera LaSuite
5.0 star property
Matera
9.6 out of 10, Exceptional, (99 reviews)
"Breakfast is good"
United States
XIAO LI
The price is 4.335.046 ₫
5.008.486 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Eurostars Matera LaSuite
Exterior

Sant'Angelo, Matera

Sant'Angelo, Matera
5.0 star property
Matera
8.8 out of 10, Excellent, (198 reviews)
"A very helpful and delightful staff, intent on making our stay as comfortable and enjoyable as possible."
United States
Paul
The price is 10.971.842 ₫
12.308.962 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Sant'Angelo, Matera
Terrace/patio

Vetera Matera

Vetera Matera
5.0 star property
Matera
9.6 out of 10, Exceptional, (19 reviews)
"Beautiful beautiful hotel and helpful staff. We will be back. We also used the spa and found it to be lovely. We loved our time there."
United States
Palle
The price is 10.159.016 ₫
11.414.854 ₫ total
includes taxes & fees
17 Jul - 18 Jul
Vetera Matera
Courtyard

BV QUARRY MATERA

BV QUARRY MATERA
5.0 star property
Matera
9.6 out of 10, Exceptional, (60 reviews)
"Lovely stay"
United States
Jaime
The price is 4.270.165 ₫
4.937.117 ₫ total
includes taxes & fees
18 Jul - 19 Jul
BV QUARRY MATERA
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Irsina.
Hotel San Domenico al Piano

Hotel San Domenico al Piano

Via Roma, 15 Matera MT
The price is 3.165.357 ₫ per night from 14 Jul to 15 Jul
3.165.357 ₫
3.721.709 ₫ total
14 Jul - 15 Jul
includes taxes & fees
8.8/10 Excellent! (242 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Irsina

Trip time! Discover the history and local cuisine in Irsina.

See all hotels in Irsina
A historic town built on a cliff with stone buildings and terracotta roofs.
Photo by Johannes Zoeteman
Open Photo by Johannes Zoeteman

Top Irsina Hotel Reviews

Aquatio Cave Luxury Hotel & SPA

Aquatio Cave Luxury Hotel & SPA

10/10 Excellent
"We found Hotel Aquatio to be a unique and truly special place — a perfect blend of luxury, history, and thoughtful modern design. The architecture and cave interiors are stunning, and every corner feels carefully considered. The service was exceptional throughout our stay. Everyone we met — from reception to the spa team, the restaurant staff, and even the cleaners — was consistently friendly, warm, and genuinely helpful. It made the whole stay feel relaxed and welcoming. The spa and pool were a real highlight. Swimming in the atmospheric cave pool was unforgettable — calming, beautiful, and unlike anything we’ve experienced before. Overall, Aquatio is a luxurious, beautifully designed hotel with outstanding service and a truly memorable atmosphere. We loved our stay and would highly recommend it."
Katie 1-night trip
Posted 2 days ago
Aquatio Cave Luxury Hotel & SPA
Palazzo Gattini Luxury Hotel

Palazzo Gattini Luxury Hotel

10/10 Excellent
"I can't say enough good things about our stay at Palazzo Gattini--the staff was incredibly helpful, kind, and fun, the location is fantastic, the whole property is beautiful, the room and amenities are top knotch, and we felt so taken care of. We will definitely recommend this hotel to anyone, and will be back again!"
Ryan 2-night trip
Posted 5 days ago
Palazzo Gattini Luxury Hotel

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Irsina?
You'll find several pricing options for a 5-star hotel in Irsina on Expedia. How much you'll pay will depend on when you want to travel, trip length and other factors. Compare available accommodation for your desired dates and use our pricing and other filters to lock in the perfect luxury stay.

  • Search for the lowest price per night from 3.067.163 ₫

What makes a hotel 5 stars in Irsina?
Faultless guest service is integral to every 5-star hotel in Irsina. From the moment you arrive, staff ensure your every need is met, whether offering luggage assistance and storage or providing a turn-down service. What's more, hotels have to offer superior amenities to be eligible for a 5-star rating. These can include luxury bath products, a wellness centre, swimming pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Irsina?
Find a luxurious getaway that includes your room, meals, activities and entertainment in Irsina with our handy filter tool. Search for hotels with a 5-star rating and click on the "All inclusive" filter. Be sure to check what's included in the upfront price. This way, you'll be ready to maximise the many perks on offer from the moment you get there.