The 10 Best 5 Star Hotels in Isernia - 2026 Updated Prices

A historic square with cobblestone pavement, classic European architecture, and a clear blue sky.

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Our top choices for Isernia 5-star hotels

A person relaxing in a hot tub with a waterfall feature, surrounded by lounge chairs and a tiled pool area.

A woman relaxing in a large, round bathtub in a hotel room with a bed and a nightstand visible in the background.

A modern living room with a large black sofa, a glass wall, and a wooden floor.

A modern hotel room with a large bathtub, a sofa, and a glass wall offering a city view.

1. Fonte Del Benessere Resort Castelpetroso - Molise

Castelpetroso

Barbara

5.557.153 ₫

6.112.868 ₫ total

includes taxes & fees

6 Oct - 7 Oct

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isernia.

Aqua Montis Resort & Spa

Via Difesa snc Rivisondoli AQ

4.546.805 ₫

5.001.485 ₫ total

15 Oct - 16 Oct

includes taxes & fees

Sport Village Hotel & Spa

Piazza del Mezzogiorno, 6 Castel di Sangro AQ

2.799.848 ₫

3.079.832 ₫ total

25 Oct - 26 Oct

includes taxes & fees

8.8/10 Excellent! (50 reviews)

Best Western Hotel Rocca

Via Sferracavalli 105 Cassino FR

2.273.646 ₫

2.588.756 ₫ total

1 Nov - 2 Nov

includes taxes & fees

8.8/10 Excellent! (138 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Isernia

Ancient stone arches frame the Fontana Fraterna, where locals gather to fill bottles with fresh spring water. Visit the Palaeolithic Museum to see 700,000-year-old tools, then sample truffle dishes at family-run restaurants in the medieval centre.

See all hotels in Isernia