A marshy landscape with water, trees, and a distant city skyline.

Compare and book 5 Star hotels in Ladys Island, Beaufort

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Check availability on Ladys Island 5 Star Hotels

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for Ladys Island 5-star hotels

A view through large windows of a landscaped garden with a circular stone feature, surrounded by potted plants.

1. Montage Palmetto Bluff

Montage Palmetto Bluff
5.0 star property
Palmetto Bluff
9.6 out of 10, Exceptional, (300 reviews)
"Staff was great Food was good"
United States
P Randall
The price is 12.359.158 ₫
15.307.552 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Montage Palmetto Bluff
An outdoor patio area with seating, umbrellas, and a view of a golf course.

2. The Inn & Club at Harbour Town

The Inn & Club at Harbour Town
5.0 star property
Sea Pines
9.6 out of 10, Exceptional, (252 reviews)
"Great stay"
United States
Lisa
The price is 7.663.194 ₫
10.558.178 ₫ total
includes taxes & fees
1 Dec - 2 Dec
The Inn & Club at Harbour Town
A two-story white colonial-style building with a central entrance, columns, and a balcony on the upper floor.

3. Anchorage 1770

Anchorage 1770
5.0 star property
Historic District
9.2 out of 10, Wonderful, (246 reviews)
"Location great. Food and service great. Beautiful property. Excellent staff."
United States
Steve
The price is 6.329.747 ₫
6.962.928 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Anchorage 1770
A historic building with a covered porch and a brick pathway.

4. Montage Palmetto Bluff Residences

Montage Palmetto Bluff Residences
5.0 star property
Palmetto Bluff
10.0 out of 10, Exceptional, (2 reviews)
"Very family friendly. Parking was a problem Check in was not one minute early. House was beautiful and very clean. Pool was wonderful Prices were high but we knew that ahead of time"
United States
john j
The price is 38.832.010 ₫
46.295.755 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Montage Palmetto Bluff Residences
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ladys Island.
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

130 Shipyard Drive Hilton Head Island SC
The price is 3.896.102 ₫ per night from 29 Nov to 30 Nov
3.896.102 ₫
5.506.147 ₫ total
29 Nov - 30 Nov
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Ladys Island

Check out the local area in Ladys Island—home to attractions like Coosaw Island and Cat Island Driving Range.

See all hotels in Ladys Island
A sunset over a water body with a wooden fence and trees with Spanish moss.
Photo by Michael Schuier
Open Photo by Michael Schuier

Top Ladys Island Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Ladys Island?
Experience top-class amenities and impeccable service at Anchorage 1770. Located around the Beaufort neighbourhood of Ladys Island, this 5-star hotel is the preferred choice for many based on reviews by Expedia's customers.
How much does it cost to stay in a 5-star hotel in Ladys Island?
You can find many different pricing options for 5-star hotels in Ladys Island on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare available properties for your desired dates and make use of our pricing and other filters to discover the perfect upscale stay.

  • Search for the lowest price per night from 4.936.954 ₫

What makes a hotel 5 stars in Ladys Island?
Exemplary guest service is the defining feature of every 5-star hotel in Ladys Island. From the moment you enter the lobby, staff attend to your every whim, whether offering luggage assistance and storage or providing in-room massages. On top of that, hotels must feature top-rate amenities to meet the standard for a 5-star rating. These can include luxury bathrobes, saunas or spas, swimming pools, fine dining kitchens and knowledgeable concierge.