Compare and book 5 Star hotels in Lignumvitae Key Botanical State Park, Islamorada

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Check availability on Lignumvitae Key Botanical State Park 5 Star Hotels

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Lignumvitae Key Botanical State Park 5-star hotels

Private beach, sun-loungers, beach umbrellas, beach towels
Cheeca Lodge & Spa

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1275)
"Fabulous waterfront, activities, and dining as well as the staff. "
Canada
David
The price is 7.868.484 ₫
10.776.665 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Cheeca Lodge & Spa
Outdoor pool
Condo in the Keys

Condo in the Keys

Condo in the Keys
5.0 star property
Tavernier
8.0 out of 10, Very good, (13)
"Love the location "
United States
Angela
Condo in the Keys
Design Villa, Canal View | Balcony
Waterfront House with Boat Dock

Waterfront House with Boat Dock

Waterfront House with Boat Dock
5.0 star property
Hammer Point
6.0 out of 10, (1)
"Covered porch was nice for time outside. Inside was in need of work. Closets unfinished, no place to put any luggage, advertises a king bed and a queen bed, but only had a king and a full, no tp, or tissue products when we arrived. None of the above were deal breakers but just allot of small things that add up to frustration."
United States
Matthew
Waterfront House with Boat Dock
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lignumvitae Key Botanical State Park.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL
The price is 6.173.734 ₫ per night from 4 Jan to 5 Jan
6.173.734 ₫
8.784.413 ₫ total
4 Jan - 5 Jan 2026
includes taxes & fees
8/10 Very Good! (1,002 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lignumvitae Key Botanical State Park

Discover the seaside area of Lignumvitae Key Botanical State Park—beaches, fresh seafood and top sights like Everglades National Park.

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Florida Keys Brewing Co. showing signage

Top Lignumvitae Key Botanical State Park Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lignumvitae Key Botanical State Park?
The amount you pay for a 5-star hotel in Lignumvitae Key Botanical State Park can vary according to the time of year you travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to land the best rate on a luxurious stay.

  • Search for the lowest price per night from 8.709.905 ₫

What makes a hotel 5 stars in Lignumvitae Key Botanical State Park?
In Lignumvitae Key Botanical State Park, a hotel must provide a certain number of upscale amenities to be designated 5 stars. These can include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may even offer thoughtful touches like a welcome gift.
Are there any 5-star all-inclusive resorts in Lignumvitae Key Botanical State Park?
Find a luxury stay that includes your room, meals, activities and entertainment in Lignumvitae Key Botanical State Park with the help of our filter tool. Search for resorts rated 5 stars and select the "All inclusive" filter. Double-check what's included in the purchase price. That way, you can take full advantage of the premium perks on offer as soon as you arrive.