A densely packed hillside town with historic architecture, a prominent church, and a rocky hilltop.

Compare and book 5 Star hotels in Nicosia, Sicily

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Nicosia 5 Star Hotels

Tonight
25 Sep - 26 Sep
Tomorrow
26 Sep - 27 Sep
This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

Our top choices for Nicosia 5-star hotels

1. Relais Santa Anastasia

Relais Santa Anastasia
Castelbuono
United States
Lincoln
4.022.887 ₫
4.425.176 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Relais Santa Anastasia
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Nicosia.
Federico II Palace Hotel

Federico II Palace Hotel

Contrada Salerno Enna EN
3.228.520 ₫
3.669.754 ₫ total
28 Sept - 29 Sept
includes taxes & fees
Federico II Palace Hotel
Mangia's Pollina Resort

Mangia's Pollina Resort

Contrada Rais-Gerbi Pollina PA
4.875.048 ₫
5.362.553 ₫ total
14 Oct - 15 Oct
includes taxes & fees
8.6/10 Excellent! (142 reviews)
Mangia's Pollina Resort
Hotel Donna Vì

Hotel Donna Vì

Via della Libertà 11 Geraci Siculo PA
2.903.510 ₫
3.193.920 ₫ total
28 Sept - 29 Sept
includes taxes & fees
9/10 Wonderful! (41 reviews)
Hotel Donna Vì
Still don't see what you're looking for?
See all properties in Nicosia.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Nicosia

Tucked into Sicily's mountainous interior, ancient Nicosia invites exploration of nearby Nebrodi Regional Park's lush forests and hidden waterfalls. Venture beyond town to discover Valley Of The Falls Mistretta's cascading waters or visit the mysterious stone pathways of Fiumara d'Arte - Arianna's Labyrinth.

See all hotels in Nicosia
A snow-capped mountain with a clear sky, rolling hills, and scattered buildings.

Top Nicosia Hotel Reviews

Relais Santa Anastasia

Relais Santa Anastasia

10/10 Excellent
"Picturesque wine country in the mountains. Beautiful setting through all the vineyards old school charm gorgeous. You feel like Medieval monastery, with its own privateChapel. Amazing service. And everyone. Great wines and olive oil. If you don't need to leave the property, you don't have to"
Selena 2-night trip
Posted 3 months ago
Relais Santa Anastasia

Explore a world of travel with Expedia