A riverside promenade with cafes, trees, and buildings.

Compare and book 5 Star hotels in Santo Antonio, Lisbon District

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santo Antonio 5 Star Hotels

Tonight
15 Sep - 16 Sep
Tomorrow
16 Sep - 17 Sep
This weekend
18 Sep - 20 Sep
Next weekend
25 Sep - 27 Sep

Our top choices for Santo Antonio 5-star hotels

A rooftop bar with a pool table, bar area, and seating, overlooking a cityscape at dusk.
A bar area with a large tree, multiple bar stools, and a view of the cityscape through large windows.
A dining table set for two with a city view, two chairs, and various glassware.
A modern building entrance with a prominent sign reading 'TIVOLI.'

1. Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
Lisbon City Center
United States
Heather
13.813.448 ₫
14.882.292 ₫ total
includes taxes & fees
9 Oct - 10 Oct
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
A modern hotel with a prominent "EPIC SANA" sign, featuring a grid-like facade and multiple floors.
A rooftop pool area with two lounge chairs, a table with a drink, and a large umbrella.
A rooftop terrace with wicker furniture, potted plants, and a city view.
A modern indoor pool area with a large ceiling projection, a hot tub, and a fireplace.

2. EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
Lisbon City Center
United States
lynn
8.633.405 ₫
9.391.446 ₫ total
includes taxes & fees
3 Oct - 4 Oct
EPIC SANA Marques Hotel
A spacious lobby with modern chandeliers, a glass staircase, and a seating area.
A swimming pool with two people in the water, overlooking a cityscape and a body of water.
A multi-story hotel with a prominent sign reading "EPIC SANA".
A modern hotel lobby with a pool, seating area, and a bar with various beverages and snacks.

3. EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
Lisbon City Center
Canada
Randy
7.235.076 ₫
7.909.218 ₫ total
includes taxes & fees
3 Oct - 4 Oct
EPIC SANA Lisboa Hotel
A hotel room with a bed, a desk, a chair, a dining area, and a bathroom with a large mirror.
A modern interior with sofas, a wooden coffee table, and a kitchen area with wooden cabinets.
A modern hotel with a prominent 'olivia' sign, multiple floors, and a well-lit facade.
A modern interior with a wooden wall, a bench, and a sign that reads 'olivia.'

4. Olivia Lisboa Hotel 5*

Olivia Lisboa Hotel 5*
Lisbon City Center
United States
lakeesha
5.400.832 ₫
5.964.919 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Olivia Lisboa Hotel 5*
A modern lobby with a polished floor, a reception desk, and a seating area with a large chandelier.
A modern living room with a sofa, armchairs, and a coffee table.
A breakfast setting with a variety of food items, drinks, and dining utensils on a table.
A hotel room with a bed, a dining table with a bottle of champagne, a plate of fruit, and a rose.

5. Eurostars Das Letras

Eurostars Das Letras
Lisbon City Center
United States
Ruthie Wing Ni
4.716.947 ₫
5.240.493 ₫ total
includes taxes & fees
27 Sept - 28 Sept
Eurostars Das Letras
An outdoor dining area with a table and chairs, surrounded by greenery and a modern building in the background.
A hotel entrance with a sign reading "138 Liberte Hotel," a red awning, and a man in a suit walking in front.
A hotel room with two beds, a desk, and a dining area.
A restaurant with a bar area, wooden tables, and hanging pendant lights.

6. 138 Liberdade Hotel

138 Liberdade Hotel
Lisbon City Center
United Kingdom
Sudha
9.436.397 ₫
10.242.618 ₫ total
includes taxes & fees
27 Sept - 28 Sept
138 Liberdade Hotel
A balcony with wicker furniture, a table, and chairs, overlooking a cityscape.
A modern building with large windows, a covered outdoor seating area, and a prominent entrance labeled 'SOFITEL.'
A modern living room with a sofa, TV, and a balcony with outdoor seating.
A breakfast buffet with various dishes, drinks, and a coffee setup.

7. Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade
Lisbon City Center
United States
jules
10.841.292 ₫
11.731.806 ₫ total
includes taxes & fees
2 Oct - 3 Oct
Sofitel Lisbon Liberdade
A modern hotel room with a large bed, a chair, a desk, and a view of the city.
A modern corridor with glass walls and a metal structure, leading to a building entrance.
A modern dining area with a long counter, seating, and a buffet.
A modern hotel lobby with a reception desk, seating area, and a staircase leading to upper floors.

8. Iberostar Selection Lisboa

Iberostar Selection Lisboa
Lisbon City Center
United States
Maura
5.266.320 ₫
5.822.336 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Iberostar Selection Lisboa
A restaurant with wooden tables and chairs, a bar area, and a large mirror.
A modern interior with a large mirror reflecting a dining area, surrounded by lush green plants.
A bar area with shelves of various liquor bottles, a coffee machine, and a cash register.
A modern lobby with a wooden reception desk, potted plants, and arched mirrors.

9. Browns Avenue Hotel

Browns Avenue Hotel
Lisbon City Center
United States
Andrew
6.951.024 ₫
7.608.614 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Browns Avenue Hotel
A rooftop bar with outdoor seating, including sofas and tables, and a view of the cityscape.
A restaurant with tables set for dining, large windows offering a city view, and potted plants.
A rooftop bar with outdoor seating, a pool, and a bar area.
A hotel lobby with a reception desk, a large abstract painting, hanging light fixtures, and a staircase.

10. Altis Grand Hotel

Altis Grand Hotel
Lisbon City Center
United Kingdom
Lisa
7.472.849 ₫
8.161.257 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Altis Grand Hotel
An outdoor seating area with wicker chairs and a large umbrella, surrounded by potted plants and a wooden deck.
A spacious room with high ceilings, arched windows, and a large glass table.
A modern interior with wooden shelves, seating, and a bar area.
A woman in a black bikini in a swimming pool with a view of a garden and outdoor furniture.

11. PortoBay Liberdade

PortoBay Liberdade
Lisbon City Center
United Kingdom
Nicola
8.350.342 ₫
9.091.400 ₫ total
includes taxes & fees
5 Oct - 6 Oct
PortoBay Liberdade
A building with ornate architectural details, including carved stonework and a balcony with wrought iron railings.
An outdoor seating area with chairs and tables, surrounded by dense ferns and a red-tiled entrance.
A bar area with a long counter, stools, and a person preparing drinks.
A rooftop pool area with lounge chairs and a large umbrella.

12. Valverde Lisboa Hotel & Garden - Relais & Châteaux

Valverde Lisboa Hotel & Garden - Relais & Châteaux
Lisbon City Center
United States
Amelia
11.898.115 ₫
12.852.247 ₫ total
includes taxes & fees
30 Sept - 1 Oct
Valverde Lisboa Hotel & Garden - Relais & Châteaux
A rooftop pool with lounge chairs and umbrellas, surrounded by greenery and buildings.
A hotel lobby with a check-in counter, seating area, and a large plant.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a glass door.
A bar area with a long counter, multiple stools, and a large illuminated wall.

13. TURIM Boulevard Hotel

TURIM Boulevard Hotel
Lisbon City Center
United States
Gary
8.282.407 ₫
9.019.389 ₫ total
includes taxes & fees
20 Sept - 21 Sept
TURIM Boulevard Hotel
A person in a swimming pool with clear water, surrounded by a tiled floor and a red wall.
A buffet with various pastries, cakes, and a fruit-topped cake on a counter.
A modern interior with a wooden reception desk, a plush armchair, a green rug, and a large plant.
A bar area with stools, a counter, and a painting on the wall.

14. The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon
Lisbon City Center
United States
eva
11.039.300 ₫
11.941.839 ₫ total
includes taxes & fees
20 Sept - 21 Sept
The Vintage Hotel & Spa - Lisbon
A rooftop pool area with a bar and seating, overlooking a cityscape.
A restaurant interior with tables set for dining, chairs, and a large window with plants outside.
A modern interior with a large window, a sofa, and a patterned rug.
A modern lounge area with a sofa, patterned rug, and a city view through large windows.

15. Memmo Príncipe Real - Design Hotels

Memmo Príncipe Real - Design Hotels
Lisbon City Center
United States
Sarah
13.785.031 ₫
14.852.661 ₫ total
includes taxes & fees
27 Sept - 28 Sept
Memmo Príncipe Real - Design Hotels
A multi-story building with classical and modern architectural styles, featuring balconies and large windows.
An elevator area with a marble wall, orange lockers, and a control panel with emergency buttons.
A bedroom with a bed, a window, a chair, and a wall-mounted light fixture.
A bright dining area with a wooden table set for breakfast, a large window with a view of buildings, and a blue patterned chair.

16. Hang your Hat

Hang your Hat
Lisbon City Center
Hang your Hat
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santo Antonio.
Locke de Santa Joana

Locke de Santa Joana

18 Rua Camilo Castelo Branco Lisbon
3.205.162 ₫
3.638.001 ₫ total
27 Sept - 28 Sept
includes taxes & fees
Locke de Santa Joana
Maxime Boutique Hotel Avenida da Liberdade

Maxime Boutique Hotel Avenida da Liberdade

Praça da Alegria, 58 Lisbon
Get rates
9.4/10 Exceptional! (876 reviews)
Maxime Boutique Hotel Avenida da Liberdade
Pestana Lisboa Vintage City Center Suites

Pestana Lisboa Vintage City Center Suites

Rua Braamcamp, 7 Lisbon
4.453.093 ₫
4.960.910 ₫ total
27 Sept - 28 Sept
includes taxes & fees
Pestana Lisboa Vintage City Center Suites
Still don't see what you're looking for?
See all properties in Santo Antonio.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santo Antonio

Wander through the elegant Avenida da Liberdade, where luxury shops line a boulevard flanked by beautiful gardens and historic squares. Take in panoramic city views at Miradouro de São Pedro de Alcântara before exploring the fascinating collections at the Medeiros e Almeida Museum.

See all hotels in Santo Antonio
A narrow street with red and white buildings, ornate street lamps, and a cobblestone path.

Top Santo Antonio Hotel Reviews

EPIC SANA Marques Hotel

EPIC SANA Marques Hotel

8/10 Good
"This hotel was lovely! Great location. The only complaint I have is that our room had an older bathroom. Some of the tiles had cracks and the bathtub/shower was close to impossible to get in and out of it. Very high. We were in the old tower which is connected to the new tower. Other than that. Our stay was comfortable and pleasant!"
Carmela 9-night trip
Posted 1 hour ago
EPIC SANA Marques Hotel
138 Liberdade Hotel

138 Liberdade Hotel

10/10 Excellent
"I highly recommend this Hotel. It is in a great location, the staff were all so friendly and accommodating and it is very clean. A special mention of Omar who was extremely exceptional in his job. You cannot go wrong with choosing here. You will love it."
DARLA 1-night trip
Posted 6 hours ago
138 Liberdade Hotel
EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel

10/10 Excellent
"La qualité du service du déjeuner et tout le reste sont magnifiques….."
Elysee 6-night trip
Posted 6 hours ago
EPIC SANA Lisboa Hotel
Olivia Lisboa Hotel 5*

Olivia Lisboa Hotel 5*

8/10 Good
"Nice hotel in a good location. Breakfast was great!"
Kenneth 6-night trip
Posted 11 hours ago
Olivia Lisboa Hotel 5*
Eurostars Das Letras

Eurostars Das Letras

10/10 Excellent
"This property was great!! The rooms were very cleaned & well maintained. The staff were very nice. I felt safe at this location. I didn’t eat, but breakfast smelled great and the bartender was attentive. The only thing missing was a pool."
Jessica 3-night trip
Posted 1 day ago
Eurostars Das Letras

Frequently asked questions

What are the best 5-star hotels in Santo Antonio?
According to reviews by our travellers, PortoBay Liberdade is one of the leading retreats for a luxurious escape in the Lisbon District neighbourhood of Santo Antonio. Want more 5-star hotels around the area? Altis Grand Hotel and Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santo Antonio?
The amount you pay for a 5-star hotel in Santo Antonio depends on things such as when you plan to go and the length of your getaway. A top tip for landing an awesome deal? Use our pricing filters to compare the available hotels for your selected dates.
  • Search for the lowest price per night from 3.638.001 ₫
What makes a hotel 5 stars in Santo Antonio?
Impeccable guest service characterises every 5-star hotel in Santo Antonio. From the instant you arrive, staff cater to your every need, whether arranging valet parking or providing in-room massages. Plus, hotels must offer upscale amenities to qualify for a 5-star rating. These can include luxury bath products, saunas or spas, pools, gastronomic restaurants and knowledgeable concierge.

Explore a world of travel with Expedia