Alexander County Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Jen - Nealys On Wheels

Top hotels in Alexander County

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 2.684.785 ₫ per night from 17 Jun to 18 Jun
2.684.785 ₫
3.028.813 ₫ total
17 Jun - 18 Jun
includes taxes & fees
9.6/10 Exceptional! (1,012 reviews)
"Wonderful room and food offerings were extra thoughtful."

Reviewed on 12 Jun 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.921.701 ₫ per night from 28 Jun to 29 Jun
2.921.701 ₫
3.359.225 ₫ total
28 Jun - 29 Jun
includes taxes & fees
9.6/10 Exceptional! (1,011 reviews)
"Evening drinks and meal were included. Breakfast was also included and very good"

Reviewed on 11 Jun 2026

Drury Inn & Suites Sikeston, MO
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 3.482.268 ₫ per night from 21 Jun to 22 Jun
3.482.268 ₫
3.928.146 ₫ total
21 Jun - 22 Jun
includes taxes & fees
9.4/10 Exceptional! (595 reviews)
"Room was very clean with plenty of space. Staff were friendly. Starbucks in lobby is convenient for breakfast. Connected to casino. Nice experience!"

Reviewed on 10 Jun 2026

The Riverview
See all 215 properties in Alexander County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Alexander County holiday package cost?
Maybe less than you might think — from as low as , actually! By combining hotels, flights and car rentals into your own tailor-made holiday package, your getaway to Alexander County is only clicks away.
How do I get a cheap travel package to Alexander County?
Our Alexander County holiday packages promise plenty of savings for the savvy wanderer. For the best deal, simply combine your flights, hotels and rental cars into a convenient package. But great bargains are just the beginning of your next unforgettable adventure. When you book with Expedia, you'll have more than 550 airlines and 1null000null000 hotel options globally to select from. Whatever your style or budget, there's a holiday package here just for you.
What are the top hotels in Alexander County?
If you're headed to Tamms, you can't go wrong with Quality Inn Cairo I-57 and Beautiful Cabin Retreat. Both are great bases for discovering this unique Alexander County city.
How far in advance should I book my Alexander County holiday?
Reserving your flights early with Expedia means one less thing to worry about. Many air carriers advertise prices up to 12 months prior to departure dates. Typically, this is the cheapest time to book. If circumstances have left you booking late, incredible deals to Alexander County sometimes emerge just a few weeks before departure.
What does an Expedia Alexander County travel package include?
Flights, hotels and a cool car for all your road trip adventures. Simply choose your favourite bundle and gain access to great discounts. Once you've made your booking, add on some tours and experiences and watch your savings grow. When it comes to creating your Alexander County getaway, you're in control!
What should I know before booking an Alexander County travel package?
Get set to save with an Expedia travel package. Combine your airfares, rental cars and hotels and score fabulous discounts. You're not limited to hotels, however. Book with us and choose from beachfront villas, chalets in the middle of mountains and even houseboats and castles!
Can I choose my airline with an Alexander County Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our holiday packages give you the flexibility to take your pick of available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Alexander County holiday package?
You can. We totally understand that life happens, so we're happy to help if you have to make changes to your Alexander County holiday package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Alexander County attractions

Fort Defiance State Park

3.7/5 (15 reviews)
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
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