Find hotels in Cape Girardeau, MO from 1.528.065 ₫

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Go beyond your typical stay in Cape Girardeau

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Check prices for these dates

Tonight
5 Nov - 6 Nov
Tomorrow
6 Nov - 7 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

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Our top choices for Cape Girardeau hotels

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is 2.443.875 ₫
2.781.473 ₫ total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
"Great stay! Hot tub was enjoyable and the staff was super friendly!"
United States
Chris
The price is 2.572.243 ₫
2.901.850 ₫ total
includes taxes & fees
10 Nov - 11 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

3. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (702 reviews)
"Great property"
United States
John
The price is 2.940.367 ₫
3.317.145 ₫ total
includes taxes & fees
9 Nov - 10 Nov
The Riverview
A spacious lobby with marble flooring, elegant seating, and a grand staircase.

4. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (557 reviews)
"The staff was very friendly and rooms were great!"
United States
Jacqueline
The price is 2.986.673 ₫
3.384.320 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott Cape Girardeau Downtown
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

5. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (858 reviews)
"Everything was lovely. Great room, breakfast, pool, and staff."
United States
Vonnie
The price is 2.510.246 ₫
2.831.909 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Cape Girardeau I 55 East
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

6. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,000 reviews)
"The stay was pleasant from start to finish. Extremely nice staff, good breakfast and convenient parking. The location was also great!"
United States
Celeste
The price is 1.851.943 ₫
2.089.251 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Pear Tree Inn Cape Girardeau West
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

7. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean, spacious suite, enjoyable kick back and breakfast!"
United States
Mary
The price is 2.314.993 ₫
2.611.636 ₫ total
includes taxes & fees
12 Nov - 13 Nov
Drury Inn & Suites Cape Girardeau
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (240 reviews)
"Great hotel…!!"
United States
Carlos
The price is 2.602.084 ₫
2.935.516 ₫ total
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau
A modern retail area with a display of local items and snacks.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is 2.193.828 ₫
2.496.883 ₫ total
includes taxes & fees
12 Nov - 13 Nov
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
"Nice clean room"
United States
James
The price is 1.826.475 ₫
2.202.008 ₫ total
includes taxes & fees
22 Nov - 23 Nov
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (818 reviews)
"Clean rooms, nice staff"
United States
Dayanita
The price is 1.528.065 ₫
1.723.871 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (243 reviews)
"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."
United States
Jaime
The price is 1.800.750 ₫
2.103.533 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Town House Inn Cape Giradreau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (890 reviews)
"Breakfast was good."
United States
J
The price is 2.055.428 ₫
2.224.487 ₫ total
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

14. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"
United States
Jeff
The price is 1.937.350 ₫
2.096.697 ₫ total
includes taxes & fees
6 Dec - 7 Dec
Comfort Suites Jackson-Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

15. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,000 reviews)
"The hotel was clean, comfortable and the breakfast was good."
United States
Leonardo
The price is 2.057.743 ₫
2.175.549 ₫ total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Jackson MO
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

16. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (450 reviews)
"Great owners "
United States
Jennifer
The price is 2.199.487 ₫
2.380.394 ₫ total
includes taxes & fees
6 Nov - 7 Nov
Town House Inn
A living room with a blue wall, a fireplace, a sofa, and a chair.

17. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is 2.704.676 ₫
2.944.039 ₫ total
includes taxes & fees
8 Nov - 9 Nov
EC Reed's Mercantile and Hotel
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

18. Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (41 reviews)
"Makanda inn is a very well maintained place. The room was very comfortable, and the staff was excellent. The breakfasts were delicious."
United States
Thomas
The price is 6.738.304 ₫
7.681.666 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Cape Girardeau attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
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Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
A nighttime view of a bridge with its cables illuminated against a starry sky.

Frequently Asked Questions

What's the weather like in Cape Girardeau?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.