Search Hotels in Central West End, St. Louis

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Our top choices for Central West End hotels

Aloft St. Louis Cortex

Aloft St. Louis Cortex
3.0 star property
Central West End
8.6 out of 10, Excellent, (825)
"Staff at the reception were very kind and friendly, made check in and out effortlessly "
United States
Elizabeth
The price is 3.056.797 ₫
3.574.282 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Aloft St. Louis Cortex

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End
9.0 out of 10, Wonderful, (683)
"Clean room, Helpful staff, Easy/cheap parking "
United States
Delaney
The price is 3.343.783 ₫
3.943.290 ₫ total
includes taxes & fees
26 Dec - 27 Dec
AC Hotel St. Louis Central West End

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1000)
"Always, a great time and place to stay."
United States
Lubna
The price is 3.769.051 ₫
5.221.808 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Royal Sonesta Chase Park Plaza St. Louis

The West End

The West End
2.0 star property
Central West End
8.6 out of 10, Excellent, (405)
"Great stay!"
United States
Shaniqua
The price is 1.839.081 ₫
2.650.541 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
The West End

Central West End B&B

Central West End B&B
3.5 star property
Central West End
7.8 out of 10, Good, (53)
"Really enjoyed the comfort. I would recommend this place to anyone. Very nice breakfast also!!! "
United States
Stacee
The price is 4.334.543 ₫
5.453.166 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Central West End B&B

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End
8.2 out of 10, Very good, (1000)
"Very friendly staff. Clean modern hotel room with comfortable bed and spacious shower! "
United States
Courtney
The price is 3.264.796 ₫
4.138.919 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Indigo St Louis - Central West End by IHG

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very good, (1000)
"Great room "
United States
Jessica
The price is 2.866.175 ₫
3.380.052 ₫ total
includes taxes & fees
21 Dec - 22 Dec
DoubleTree by Hilton St. Louis Forest Park

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 6 km from Central West End
8.8 out of 10, Excellent, (1242)
"Great hospitality"
United States
Alejandro
The price is 2.822.469 ₫
3.356.733 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton St. Louis Downtown

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 5.9 km from Central West End
9.4 out of 10, Exceptional, (1096)
"Great staff"
United States
Phillip
The price is 3.923.021 ₫
4.665.611 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Live by Loews - St.Louis

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 6.3 km from Central West End
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
The price is 4.449.601 ₫
5.202.874 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Missouri Athletic Club

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 6.4 km from Central West End
8.6 out of 10, Excellent, (1164)
"The room was clean and the staff were extremely friendly and personable! "
United States
Shannon
The price is 2.506.521 ₫
2.930.851 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 6.4 km from Central West End
8.4 out of 10, Very good, (4003)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is 2.345.914 ₫
2.766.512 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Regency St. Louis at The Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 6.3 km from Central West End
8.8 out of 10, Excellent, (1014)
"My second time staying there as always it was lovely "
United States
Nina
The price is 2.717.153 ₫
3.204.312 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Pennywell St. Louis at the Arch

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
24.2 km from Central West End
8.4 out of 10, Very good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 4.005.957 ₫
5.118.358 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Ameristar Casino Resort and Spa

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 6.3 km from Central West End
9.4 out of 10, Exceptional, (3275)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is 3.554.152 ₫
4.155.834 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel St. Louis at the Arch

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
4.7 km from Central West End
9.4 out of 10, Exceptional, (440)
"The hotel is beautiful and the staff is very helpful and kind. "
United States
Beth
The price is 3.334.568 ₫
3.834.354 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
The Knight Center at Washington University

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 4.6 km from Central West End
8.4 out of 10, Very good, (1006)
"Nice historic hotel"
United States
Michelle
The price is 3.735.032 ₫
4.442.038 ₫ total
includes taxes & fees
21 Dec - 22 Dec
St. Louis Union Station Hotel, Curio Collection by Hilton

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
24 km from Central West End
9.2 out of 10, Wonderful, (1001)
"Staff was very nice and the room was clean and comfortable."
United States
Deborah
The price is 2.474.663 ₫
2.795.877 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites St. Louis Fairview Heights

The Cheshire

The Cheshire
4.0 star property
4.4 km from Central West End
8.6 out of 10, Excellent, (1003)
"Excellent place to stay. "
United States
Todd
The price is 3.031.078 ₫
3.599.041 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Cheshire

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
2.4 km from Central West End
8.8 out of 10, Excellent, (1034)
"This was a wonderful first experience at a beautiful hotel with such friendly staff. We will definitely stay here again!"
United States
Alexis
The price is 3.133.144 ₫
3.694.884 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Central West End

Find the best Central West End areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Central West End Hotel Reviews

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Frequently asked questions

What is Central West End like?
Central West End is a neighbourhood that people enjoy for its popular theatre scene. Consider a visit to World Chess Hall of Fame as part of your Central West End travel plans.
How many hotels can I expect to find in Central West End?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 136 Central West End hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Central West End, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Central West End.
What is there to do in this St. Louis neighbourhood?
World Chess Hall of Fame is an attraction you might want to check out while you're in Central West End. When you're sightseeing in St. Louis, St. Louis Union Station and Highlands Golf & Tennis Center are also worth a stop.
How can I get around Central West End and the greater St. Louis area?
Ready to get out and explore the city? Central West End Station is the closest metro station.