Search Hotels in Desoto Lakes, Sarasota

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Our top choices for Desoto Lakes hotels

Kompose Boutique Hotel

Kompose Boutique Hotel
3.0 star property
6.1 km from Desoto Lakes
9.2 out of 10, Wonderful, (4776)
"Would happily stay here again!"
United States
STYLIANOS
Kompose Boutique Hotel

Motel 6 Venice, FL

Motel 6 Venice, FL
2.0 star property
30.4 km from Desoto Lakes
8.4 out of 10, Very good, (371)
"We enjoyed the service and the room and the staff it was excellent Thank you ☺️ "
United States
Fred
The price is 1.538.696 ₫
1.784.666 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Motel 6 Venice, FL

Golden Host Resort - Sarasota

Golden Host Resort - Sarasota
3.0 star property
6.3 km from Desoto Lakes
8.4 out of 10, Very good, (2165)
"Great Place To Stay!"
United States
Pete
Golden Host Resort - Sarasota

Inn at the Beach

Inn at the Beach
3.0 star property
30.4 km from Desoto Lakes
9.8 out of 10, Exceptional, (1015)
"Very nice employees, great continental breakfast and very close to everything "
United States
Joseph
The price is 4.819.442 ₫
6.129.531 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Inn at the Beach

Quality Inn - Near Serenoa Golf Club

Quality Inn - Near Serenoa Golf Club
2.5 star property
12 km from Desoto Lakes
7.2 out of 10, Good, (1004)
"My review is based on motels that sre less than 100$ a night. Very pleased with the place and would definitely return. "
United States
Alan
The price is 1.893.841 ₫
2.140.040 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Quality Inn - Near Serenoa Golf Club

Compass Hotel by Margaritaville Anna Maria Sound

Compass Hotel by Margaritaville Anna Maria Sound
4.0 star property
24 km from Desoto Lakes
9.4 out of 10, Exceptional, (1882)
"Very nice stay; wonderful staff"
United States
Karen
The price is 4.002.610 ₫
5.266.123 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Compass Hotel by Margaritaville Anna Maria Sound

Spark by Hilton Sarasota Siesta Key Gateway

Spark by Hilton Sarasota Siesta Key Gateway
3.0 star property
12.9 km from Desoto Lakes
8.4 out of 10, Very good, (1859)
"Great stay once again "
United States
troy
The price is 2.609.654 ₫
2.948.910 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Spark by Hilton Sarasota Siesta Key Gateway

Regency Inn & Suites

Regency Inn & Suites
2.5 star property
6.2 km from Desoto Lakes
7.4 out of 10, Good, (1005)
"staff were friendly, room was clean. so.ple breakfast, but was all we needed."
United States
Nicholas
Regency Inn & Suites

Escape Coastal Resort on Casey Key

Escape Coastal Resort on Casey Key
2.5 star property
27.3 km from Desoto Lakes
9.8 out of 10, Exceptional, (237)
"Very nice place right across the street from the beach"
United States
Erica
Escape Coastal Resort on Casey Key

Ramada by Wyndham Venice Hotel Venezia

Ramada by Wyndham Venice Hotel Venezia
3.5 star property
30.2 km from Desoto Lakes
7.2 out of 10, Good, (1002)
"the one bed suites are very spacious and comfortable, very nice for an extended stay. The pool area is beautiful, but the pool is not heated. The bar and restaurant staff are fabulous and the food is great."
United States
Alan
The price is 2.709.621 ₫
3.061.872 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Ramada by Wyndham Venice Hotel Venezia

Comfort Suites Sarasota - Siesta Key

Comfort Suites Sarasota - Siesta Key
3.0 star property
11.4 km from Desoto Lakes
9.2 out of 10, Wonderful, (1891)
"Welcoming staff, clean & comfortable room, with great location for my needs."
United States
Eugene
The price is 3.065.818 ₫
3.464.374 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Comfort Suites Sarasota - Siesta Key

Holiday Inn Express & Suites Nokomis Sarasota South by IHG

Holiday Inn Express & Suites Nokomis Sarasota South by IHG
2.5 star property
27.6 km from Desoto Lakes
9.6 out of 10, Exceptional, (360)
"Very clean hotel. Great service and very clean and comfortable room"
United States
Iris
The price is 2.893.770 ₫
3.269.961 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Holiday Inn Express & Suites Nokomis Sarasota South by IHG

Siesta Key Palms Resort

Siesta Key Palms Resort
3.5 star property
13.1 km from Desoto Lakes
9.2 out of 10, Wonderful, (1003)
"This place was wonderful, clean "
United States
Alan
Siesta Key Palms Resort

Hampton Inn Sarasota - I-75 Bee Ridge

Hampton Inn Sarasota - I-75 Bee Ridge
2.5 star property
8.8 km from Desoto Lakes
8.6 out of 10, Excellent, (340)
"Everything was great!"
United States
Juan
The price is 2.504.426 ₫
2.830.002 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn Sarasota - I-75 Bee Ridge

Tropical Beach Resorts

Tropical Beach Resorts
3.5 star property
14.3 km from Desoto Lakes
9.4 out of 10, Exceptional, (5151)
"Great place, easy beach access and property was beautiful. "
United States
Maria
The price is 3.331.782 ₫
4.359.452 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Tropical Beach Resorts

Casey Key Resorts - Beachfront

Casey Key Resorts - Beachfront
2.0 star property
27.2 km from Desoto Lakes
8.8 out of 10, Excellent, (1000)
"Real nice and comfortable small hotel right on the beach. Will certainly make a return visit in the future."
United States
Andris
The price is 3.403.784 ₫
4.307.829 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Casey Key Resorts - Beachfront

Tropical Breeze Resort

Tropical Breeze Resort
3.0 star property
13 km from Desoto Lakes
9.0 out of 10, Wonderful, (1008)
"Great stay, walking distance to the beach and restaurants! "
United States
Joseph
The price is 4.195.361 ₫
5.309.648 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Tropical Breeze Resort

Quality Inn Bradenton - Sarasota North

Quality Inn Bradenton - Sarasota North
2.5 star property
10 km from Desoto Lakes
7.6 out of 10, Good, (1003)
"Room was clean, quiet and comfortable bed"
United Kingdom
Anne
The price is 1.766.515 ₫
1.996.161 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Quality Inn Bradenton - Sarasota North

Comfort Inn & Suites Sarasota I75

Comfort Inn & Suites Sarasota I75
2.5 star property
Fruitville, 5.2 km from Desoto Lakes
8.6 out of 10, Excellent, (1001)
"Very nice and clean hotel, the breakfast lady, front desk person and housekeepers are very helpful and friendly."
United States
Zuleima
The price is 3.048.981 ₫
3.445.349 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Comfort Inn & Suites Sarasota I75

Extended Stay America Premier Suites - Bradenton

Extended Stay America Premier Suites - Bradenton
2.5 star property
8.3 km from Desoto Lakes
9.0 out of 10, Wonderful, (368)
"Clean and just what we needed for a quick stay"
United States
Golan
The price is 2.343.691 ₫
2.648.589 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Extended Stay America Premier Suites - Bradenton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Desoto Lakes

Find the best Desoto Lakes areas for the activities you enjoy most.

South Sarasota

While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.

Central Sarasota

Gardens, art galleries and theatres highlight some of the noteworthy features of Central Sarasota. Make a stop by Sarasota Opera House or Marina Jack while you're exploring the neighbourhood.

Downtown Sarasota

While visiting Downtown Sarasota, you might make a stop by sights like Sarasota Opera House and Regal Hollywood - Sarasota.

Palmer Ranch

While there might not be top attractions in Palmer Ranch, you can explore the larger area and discover places like Stoneybrook Golf & Country Club and Sarasota Square.

Southgate

While there might not be top attractions in Southgate, you can explore the larger area and discover places like Lido Beach and Siesta Key Beach.

Top Desoto Lakes Hotel Reviews

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Frequently asked questions

What's it like in Desoto Lakes?
Desoto Lakes is a neighbourhood that travellers like for its beaches, shopping and restaurants.
How many hotels will I be able to find in the Desoto Lakes area?
Book one of Expedia's 7 hotels and other accommodation options in Desoto Lakes and start exploring everything Sarasota has to offer.
If I need to cancel my hotel reservation in Desoto Lakes, will I receive a refund?
Yes! Most hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to review top deals in Desoto Lakes.
What is there to do around this Sarasota neighbourhood?
A few places to visit in the area around Desoto Lakes include Northeast Plaza Shopping Center, Rolling Green Golf Club and Bobby Jones Golf Complex. While you're out sightseeing, Sarasota Commons Shopping Center and Ed Smith Stadium are a couple of additional sights to visit in Sarasota.