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Check availability on Downtown San Diego Spa Hotels

Our top choices for Downtown San Diego hotels with a spa

Body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1857)
"Enjoyed my stay"
United States
Brandon
The price is 2.648.879 ₫
4.364.424 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hilton San Diego Bayfront
Facials, 2 treatment rooms, massages
The Westin San Diego Bayview

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1061)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is 3.563.466 ₫
4.895.750 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Dinner served
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2048)
"It was an amazing stay "
United States
Alejandra
The price is 4.906.580 ₫
6.880.797 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Omni San Diego Hotel at the Ballpark
Body treatments, hydrotherapy, aromatherapy, hot stone massages
Westgate Hotel

Westgate Hotel

Westgate Hotel
4.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1004)
"Beautiful hotel, clean and very friendly staff! Beds were comfortable, we enjoyed our stay."
United States
Somer
Westgate Hotel
Body treatments, deep-tissue massages, Swedish massages
Pendry San Diego

Pendry San Diego

Pendry San Diego
5.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1003)
"Excellent Stay at Pendry - will definitely return when visiting San Diego"
Canada
Bobbi Jo
The price is 6.721.035 ₫
9.176.974 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Pendry San Diego
Suite, 1 King Bed with Sofa bed, Bay View | Bathroom | Free toiletries, hair dryer, towels
The Westin San Diego Gaslamp Quarter

The Westin San Diego Gaslamp Quarter

The Westin San Diego Gaslamp Quarter
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1001)
"Check-in staff was excellent "
United States
Robin
The price is 3.795.408 ₫
5.168.239 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Gaslamp Quarter
Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1570)
"Loved our stay "
United States
Jeremy
The price is 3.060.048 ₫
4.911.921 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hyatt Regency Mission Bay Spa and Marina
Reception
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
Point Loma
8.8 out of 10, Excellent, (1554)
"Every time i have stayed here everything is always clean...no complaints!"
United States
Joseline
The price is 3.015.241 ₫
3.465.869 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Island Palms Hotel & Marina
Couples treatment room(s), body treatments, hot stone massages
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2943)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is 4.010.218 ₫
4.609.544 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Legacy Resort Hotel & Spa
Hot stone massages, prenatal massages, sports massages, body scrubs
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is 3.097.870 ₫
4.747.645 ₫ total
includes taxes & fees
17 Dec - 18 Dec
San Diego Mission Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown San Diego Hotel Reviews

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent
"Hotel was great, no regrets at all."
Gabriel 2-night trip
Posted 6 days ago
Courtyard by Marriott San Diego Downtown Little Italy

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Frequently asked questions

Looking to holiday at a spa hotel in Downtown San Diego?
Soothe the senses with some time in one of our wonderful spa hotels. Travellers love the fascinating museums and bars in Downtown San Diego. Enjoy the art galleries and many popular restaurants during your holiday. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your weekend away.
How many spa hotels are there in Downtown San Diego?
Among Expedia's 790 accommodation options in Downtown San Diego, there are 4 spa hotels.
What's there to see and do in Downtown San Diego?
Experience all that Downtown San Diego has to offer when you visit Petco Park, Port of San Diego and San Diego Civic Theatre. If you have a little extra time during your trip, you might want to make a stop at Seaport Village and Navy Pier.
What is a Downtown San Diego spa hotel?
Spa hotels in Downtown San Diego have on-site spas and offer services such as massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.