Search Business Hotels in Downtown San Francisco

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Downtown San Francisco Business Hotels

Next weekend
In two weeks

Top Downtown San Francisco Business Hotels

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6932)
"It was very close to tourist points, breakfast was superb!"
The price is 3.985.358 ₫
5.778.370 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Hotel Riu Plaza Fisherman's Wharf

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1321)
"The location was great"
The price is 3.590.808 ₫
4.768.647 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Hyatt Regency San Francisco Airport

Harbor View Inn

2.0 star property
9.0 out of 10, Wonderful, (577)
"Easy parking, friendly staff, coffee and sodas available 24 hrs"
Harbor View Inn

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
9.4 out of 10, Exceptional, (1309)
"Lovely stay"
The price is 4.668.050 ₫
6.547.542 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Hyatt Regency San Francisco Downtown SOMA

San Francisco Marriott Marquis

4.0 star property
8.8 out of 10, Excellent, (1273)
"Super nice & elegant hotel"
The price is 4.752.540 ₫
6.536.854 ₫ total
includes taxes & fees
17 Oct - 18 Oct
San Francisco Marriott Marquis

The Westin St. Francis San Francisco on Union Square

4.5 star property
8.8 out of 10, Excellent, (2493)
"Staff were excellent!"
The price is 4.462.107 ₫
6.348.733 ₫ total
includes taxes & fees
17 Oct - 18 Oct
The Westin St. Francis San Francisco on Union Square

Hyatt Regency San Francisco

4.0 star property
9.2 out of 10, Wonderful, (1920)
"Hotel was beautiful! "
The price is 4.990.167 ₫
7.114.024 ₫ total
includes taxes & fees
2 Oct - 3 Oct
Hyatt Regency San Francisco

InterContinental San Francisco by IHG

4.0 star property
9.0 out of 10, Wonderful, (1028)
"Great location, friendly staff and comfy beds!"
The price is 4.726.137 ₫
6.650.388 ₫ total
includes taxes & fees
17 Oct - 18 Oct
InterContinental San Francisco by IHG

Hotel VIA

4.0 star property
9.2 out of 10, Wonderful, (1440)
"Fantastic stay!"
The price is 5.679.285 ₫
6.684.235 ₫ total
includes taxes & fees
19 Oct - 20 Oct
Hotel VIA

Grand Hyatt San Francisco

4.0 star property
8.8 out of 10, Excellent, (1021)
"Very nice hotel with great location!"
The price is 4.250.883 ₫
6.246.129 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Grand Hyatt San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown San Francisco Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Why book your business-friendly hotel in Downtown San Francisco with Expedia?
At Expedia, our top task is to help you locate an excellent stay at the right price. From luxurious, corporate-friendly escapes to affordable hotels filled with conveniences, you'll have your next work trip arranged in a couple of clicks.
How can I find cheap business-friendly hotels in Downtown San Francisco?
When work takes you to Downtown San Francisco, our "business friendly" filter will help you find the perfect hotel. From fast WiFi to conference spaces and in-room desks, they have the amenities you need to do your job. You can also refine your search by your preferred star rating and budget to view the most affordable stays.