Search Boutique Hotels in Downtown St. Louis

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Check availability on Downtown St. Louis Boutique Hotels

Tonight
20 Dec - 21 Dec
Tomorrow
21 Dec - 22 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Our top choices for Downtown St. Louis boutique hotels

Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1916)
"Clean rooms, good coffee and fresh muffins and friendly service."
United States
Colleen
The price is 2.964.579 ₫
3.525.745 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Moonrise Hotel
Gastropub
The Cheshire

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1003)
"Excellent place to stay. "
United States
Todd
The price is 3.078.853 ₫
3.655.768 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
The Cheshire
Front of property
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very good, (577)
"Love this place."
United States
Robert
The price is 3.210.430 ₫
3.997.007 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown St. Louis Hotel Reviews

Frequently asked questions

What's there to see and do in Downtown St. Louis?
Visitors speak positively about this destination's acclaimed theatres, great live music and top museums. Activities and attractions to experience around Downtown St. Louis include Gateway Arch, Museum at the Gateway Arch and Cardinals Hall of Fame and Museum. You might also want to see spots like St. Louis Union Station, Gateway Arch National Park and Kiener Plaza during your trip.
What's the best way to get to my boutique hotel in Downtown St. Louis?
You have a few options for travelling to and around Downtown St. Louis. The nearest major airport is Lambert-St. Louis International Airport (STL), which is located 12.5 mi (20.1 km) away. Nearby metro stations include 8th and Pine Station, Stadium Station and Convention Center Station.