East Prairie Holidays

Book a Hotel + Flight or Car together to unlock savings

Top hotels in East Prairie

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.922.922 ₫ per night from 10 Aug to 11 Aug
2.922.922 ₫
3.360.629 ₫ total
10 Aug - 11 Aug
includes taxes & fees
Drury Inn & Suites Sikeston, MO
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.439.674 ₫ per night from 16 Aug to 17 Aug
2.439.674 ₫
2.780.618 ₫ total
16 Aug - 17 Aug
includes taxes & fees
8.4/10 Very good! (1,007 reviews)
"Good location. Other nearby hotels were questionable, but felt safe in Best Western."

Reviewed on 28 Jul 2026

Best Western Plus Sikeston I-55
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 1.790.780 ₫ per night from 9 Aug to 10 Aug
1.790.780 ₫
2.041.041 ₫ total
9 Aug - 10 Aug
includes taxes & fees
7.2/10 Good! (1,000 reviews)
"Unfortunately the room I booked was extremely dirty… there were massive dark stains on the white sheets when first walking in. I asked for a new sheet and when I came to out the new one on- it too had lighter stains and tiny curly hairs all over it. The floors were uncleaned, bathroom still had hair ..."

Reviewed on 28 Jul 2026

Days Inn and Suites by Wyndham Sikeston
See all 90 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
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Frequently asked questions

How much does an East Prairie holiday package cost?
Offering excellent value package deals on Expedia, you'll be thrilled with how little a holiday to East Prairie costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to East Prairie?
If you're hoping to book a cheap East Prairie holiday package, consider travelling in January, February and November. You'll generally find lower prices on flights and accommodation during these months — ideal for a budget-friendly getaway.
How many days is enough for East Prairie?
With a well-organised schedule, you can easily tick off the most popular East Prairie attractions in a few days. But if you prefer to discover lesser-known spots or go on day tours, think about booking your East Prairie holiday for longer.
How to find the best East Prairie package deals?
Landing a cheap East Prairie package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can personalise your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most wallet-friendly East Prairie package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider travelling on a weekday, when prices are typically lower.
Is it cheaper to book an East Prairie holiday as a package?
An Expedia holiday package could score you significant savings when compared to booking hotels and flights individually. Better still, you can tailor your East Prairie trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a holiday package to East Prairie?
Enjoy amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment East Prairie getaway.
How to plan a trip to East Prairie?

  1. Choose the perfect time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to go to East Prairie.
  2. Budget wisely: Besides the price of your accommodation, you'll need to consider other expenses too. These include transportation, food and flights. Also, put aside some extra funds for unexpected expenses that may crop up during your trip to East Prairie.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you want to experience in East Prairie. Then, estimate how long you'll need for each, along with any travel time.
  4. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left now is to pick an East Prairie holiday package that brings all your bookings together.