
Eastern Panama Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Nico Barner
Top hotels in Eastern Panama

Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
Fully refundableReserve now, pay when you stay
10/10 Exceptional! (2 reviews)
Great location for bird watching! The hosts were friendly and helpful. It is best to contact them directly using WhatsApp in addition to booking on Expedia.
Reviewed on 13 Feb 2026

Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
The price is 1.724.412 ₫ per night from 8 Mar to 9 Mar
1.724.412 ₫
3.048.905 ₫ total
8 Mar - 9 Mar
includes taxes & fees

Ordovician Beach Resort
Isla Grande Isla Grande Colon
The price is 13.078.408 ₫ per night from 8 Mar to 9 Mar
13.078.408 ₫
14.386.249 ₫ total
8 Mar - 9 Mar
includes taxes & fees
10/10 Exceptional! (9 reviews)
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on 21 Feb 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Isla Diablo
Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.
Isla Chichime
Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.
Museum of the Kuna Nation
You can spend an afternoon browsing the exhibits at Museum of the Kuna Nation during your travels in Narganá. Stroll along the seaside or experience the area's festivals.
