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13 Dec - 14 Dec
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14 Dec - 15 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Grand Center hotels

Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1034)
"Fun staff and a very cool hotel. Great room, too!"
United States
Christopher
The price is 3.135.794 ₫
3.698.010 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Lobby
White House at Grand Central

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
The price is 1.784.017 ₫
3.777.860 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
White House at Grand Central
Front of property
Grand Center Inn

Grand Center Inn

Grand Center Inn
3.0 star property
Grand Center
9.4 out of 10, Exceptional, (70)
"Great! "
United States
mike
The price is 4.708.953 ₫
5.553.221 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Grand Center Inn
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 4.2 km from Grand Center
8.4 out of 10, Very good, (4007)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is 2.213.734 ₫
2.610.635 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Regency St. Louis at The Arch
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
16.2 km from Grand Center
9.4 out of 10, Exceptional, (2754)
"The room was clean and staff were very friendly."
United States
Denise
The price is 2.367.367 ₫
2.786.964 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Pear Tree Inn St. Louis Airport
Exterior
Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel
2.5 star property
15 km from Grand Center
9.2 out of 10, Wonderful, (1001)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
The price is 2.884.563 ₫
3.567.955 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Best Western Plus St. Louis Airport Hotel
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 3.7 km from Grand Center
8.8 out of 10, Excellent, (1148)
"Really nice hotel!"
United States
DARIN
The price is 2.296.601 ₫
2.731.323 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Exterior
Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.3 km from Grand Center
9.4 out of 10, Exceptional, (700)
"Great breakfast ! "
United States
Jeanette
The price is 2.446.551 ₫
2.715.182 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Troy by IHG
Property amenity
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 4.1 km from Grand Center
9.4 out of 10, Exceptional, (3277)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is 3.551.182 ₫
4.152.361 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Drury Plaza Hotel St. Louis at the Arch
Lobby sitting area
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
23.5 km from Grand Center
7.4 out of 10, Good, (1001)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is 1.685.752 ₫
1.955.270 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Front of property
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 4.1 km from Grand Center
8.8 out of 10, Excellent, (1014)
"My second time staying there as always it was lovely "
United States
Nina
The price is 2.714.882 ₫
3.201.633 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hilton Pennywell St. Louis at the Arch
Indoor pool
Hampton Inn O'Fallon

Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
27 km from Grand Center
9.2 out of 10, Wonderful, (811)
"Very nice rooms, clean and quiet!"
United States
Michael
The price is 2.567.037 ₫
2.977.249 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn O'Fallon
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
26.4 km from Grand Center
9.4 out of 10, Exceptional, (1003)
"Great service - quaint location"
United States
Kim
The price is 2.935.861 ₫
3.374.096 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Country Inn & Suites by Radisson, St. Charles Historic District
Lobby
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
22.3 km from Grand Center
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is 2.293.970 ₫
2.545.847 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn St. Louis - Columbia
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 3.1 km from Grand Center
7.6 out of 10, Good, (585)
"Everything great….very nice staff and security….delicious breakfast!!"
Canada
Derek
The price is 2.135.602 ₫
2.497.138 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
5 restaurants, breakfast, lunch, dinner served; American cuisine
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
12.8 km from Grand Center
9.0 out of 10, Wonderful, (1446)
"Awesome place to stay!!"
United States
Kaitlyn
The price is 2.314.753 ₫
3.076.341 ₫ total
includes taxes & fees
15 Dec - 16 Dec
River City Casino & Hotel
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.2 km from Grand Center
8.8 out of 10, Excellent, (3032)
"Clean room, good breakfast and good location "
United States
Martin
The price is 2.365.473 ₫
2.761.406 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay
Exterior
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.5 km from Grand Center
9.2 out of 10, Wonderful, (817)
"Always a good stay here!"
United States
Chelsie
The price is 3.051.612 ₫
3.508.743 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG
Free daily continental breakfast
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
16.2 km from Grand Center
9.2 out of 10, Wonderful, (1501)
"The room was very clean and the staff was very helpful."
United States
John
The price is 2.839.841 ₫
3.343.620 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Wingate by Wyndham St. Louis Airport
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
26.5 km from Grand Center
9.6 out of 10, Exceptional, (1002)
"The stay was perfect. Very clean, quiet and comfortable. The staff were very friendly and helpful. I will stay again. "
United States
holly
The price is 3.025.042 ₫
3.506.723 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Grand Center

Find the best Grand Center areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Top Grand Center Hotel Reviews

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Frequently asked questions

What's it like in Grand Center?
Grand Center is a neighbourhood that travellers like for its theatre scene and opera houses. Make sure that you visit Powell Symphony Hall and St. Louis Symphony Orchestra as part of your Grand Center travel plans.
How many hotels will I find in Grand Center?
Expedia has 31 hotels and other accommodation options in Grand Center to choose from, making this an ideal home base for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Grand Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Center.
What are the top things to see and do in Grand Center?
While you're in Grand Center, you can catch a show at Powell Symphony Hall, St. Louis Symphony Orchestra and Sheldon Concert Hall. Fox Theater and Grandel Theater are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Gateway Arch are some popular places to visit in the area around Grand Center. While you're out sightseeing in St. Louis, make sure that you visit other sights such as Urban League St. Louis or Vaughn Cultural Center.