A nighttime pedestrian bridge with illuminated railings and a rainbow-colored light projection on the floor.

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Check prices for these dates

This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

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Our top choices for Greater South Side hotels

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

1. Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1,818 reviews)
"The pool was warm, the staff was great, clean room, hot water, breakfast was decent. Great price, great stay."
United States
Amanda
The price is 1.699.998 ₫
1.903.998 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Days Inn & Suites by Wyndham Des Moines Airport
A spacious hotel lobby with a central bar, seating area, and a ceiling fan.

2. Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1,001 reviews)
"Great place to stay and is real close to the airport"
United States
Jayson
The price is 2.427.634 ₫
2.718.950 ₫ total
includes taxes & fees
24 Oct - 25 Oct
Hampton Inn Des Moines-Airport
Breakfast area

3. Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.6 out of 10, Good, (1,000 reviews)
"Reasonable price close to airport"
United States
Barbara
The price is 1.655.205 ₫
1.853.830 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Quality Inn & Suites Des Moines Airport
A reception desk with a sign reading "AmericInn" and a clock on the wall.

4. AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
3.0 star property
Greater South Side
8.0 out of 10, Very good, (1,017 reviews)
"Great place"
United States
Milagros
The price is 1.566.927 ₫
1.754.958 ₫ total
includes taxes & fees
15 Oct - 16 Oct
AmericInn by Wyndham Des Moines Airport
A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
Greater South Side
8.4 out of 10, Very good, (727 reviews)
"Great place to stay"
United States
Reginald
The price is 2.959.896 ₫
3.315.084 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Des Moines-Airport/Conf Center by IHG
A spacious lobby with high ceilings, large windows, and a chandelier.

6. Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 3.7 km from Greater South Side
9.6 out of 10, Exceptional, (1,352 reviews)
"Great stay!"
United States
Sonya
The price is 3.727.269 ₫
4.174.541 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Hotel Fort Des Moines, Curio Collection by Hilton
A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

7. Des Lux Hotel

Des Lux Hotel
3.5 star property
Court District, 3.9 km from Greater South Side
9.8 out of 10, Exceptional, (1,112 reviews)
"What a great place to stay. It is a beautiful hotel with a nice lounge, wonderful breakfast and super friendly staff."
United States
Heidi
The price is 3.949.124 ₫
4.423.227 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Des Lux Hotel
A spacious lobby with a bar area, seating arrangements, and a high ceiling with recessed lighting.

8. Des Moines Marriott Downtown

Des Moines Marriott Downtown
3.5 star property
Downtown Des Moines, 4.1 km from Greater South Side
8.8 out of 10, Excellent, (1,001 reviews)
"Hotel was clean and enjoyed our stay."
United States
Nancy
The price is 3.505.140 ₫
3.925.757 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Des Moines Marriott Downtown
A Holiday Inn Express building with a brick facade, multiple windows, and a covered entrance.

9. Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines, 3.2 km from Greater South Side
9.2 out of 10, Wonderful, (1,001 reviews)
"Would stay there again."
United States
Meg
The price is 2.883.114 ₫
3.229.088 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Express & Suites Des Moines Downtown by IHG
A hotel facade with a prominent sign reading "SAVERY HOTEL" and "Renaissance Hotel."

10. Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel
3.5 star property
Downtown Des Moines, 4.2 km from Greater South Side
8.6 out of 10, Excellent, (1,000 reviews)
"Great place!"
United States
Jayson
The price is 3.712.852 ₫
4.158.394 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Renaissance Des Moines Savery Hotel
An outdoor dining area with tables and chairs, a large umbrella, and a TV screen.

11. Hilton Des Moines Downtown

Hilton Des Moines Downtown
3.5 star property
Downtown Des Moines, 4.5 km from Greater South Side
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay! The bartenders were amazing!"
United States
Sweta
The price is 3.535.581 ₫
4.078.552 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Hilton Des Moines Downtown
A modern bar with wooden shelves and a long counter.

12. Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection
4.0 star property
Court District, 3.8 km from Greater South Side
9.4 out of 10, Exceptional, (1,000 reviews)
"Close to everything we needed down town."
United States
Ryan
The price is 4.387.916 ₫
4.914.465 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Surety Hotel, Autograph Collection
An outdoor seating area with a circular fire pit, wicker furniture, and string lights.

13. Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown
3.0 star property
Court District, 3.9 km from Greater South Side
8.8 out of 10, Excellent, (684 reviews)
"This is a clean, pleasant, and familiar place to stay with a great location near the ballpark and Court Avenue district."
United States
Michael
The price is 2.948.568 ₫
3.302.396 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Residence Inn Des Moines Downtown
A modern kitchen with dark cabinets, stainless steel appliances, and a tiled backsplash.

14. Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 4.5 km from Greater South Side
9.2 out of 10, Wonderful, (1,000 reviews)
"Terrific location, great happy hour, nice staff. Would definitely stay here again"
United States
Dawn R.
The price is 3.063.752 ₫
3.431.402 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Staybridge Suites Des Moines Downtown by IHG
A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

15. Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center
2.5 star property
Downtown Des Moines, 4.9 km from Greater South Side
8.8 out of 10, Excellent, (1,011 reviews)
"Would stay there again."
United States
Mario
The price is 2.405.565 ₫
2.694.232 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn & Suites Event Center
An outdoor patio area with tables and chairs, a fire pit, and string lights.

16. Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown
4.0 star property
Downtown Des Moines, 4.8 km from Greater South Side
9.0 out of 10, Wonderful, (524 reviews)
"Friendly staff. I would have liked to stay longer!"
United States
Charles
The price is 2.405.565 ₫
2.694.232 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Des Moines Downtown
An outdoor dining area with a table set for two, featuring a cocktail and candles.

17. Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown
3.5 star property
Historic East Village, 4.4 km from Greater South Side
8.4 out of 10, Very good, (1,001 reviews)
"Such a wonderful hotel and amazing staff and fantastic rooms!"
United States
Candy
The price is 3.386.490 ₫
3.792.869 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Embassy Suites Hotel Des Moines Downtown
A multi-story hotel with a classic brick facade, large windows, and a prominent Liberty Building sign.

18. Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown
3.0 star property
Downtown Des Moines, 4.1 km from Greater South Side
8.2 out of 10, Very good, (1,001 reviews)
"Very nice hotel will stay there again"
United States
Felicia
The price is 2.856.040 ₫
3.198.765 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Hyatt Place Des Moines/Downtown
A modern dining area with a large island table, multiple chairs, and a chandelier.

19. Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown
2.5 star property
Court District, 3.9 km from Greater South Side
8.6 out of 10, Excellent, (1,009 reviews)
"Good spot to be downtown. Next the baseball field"
United States
David A
The price is 2.746.472 ₫
3.076.049 ₫ total
includes taxes & fees
7 Oct - 8 Oct
Hampton Inn & Suites Des Moines Downtown
An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

20. Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake, 5.6 km from Greater South Side
9.4 out of 10, Exceptional, (1,001 reviews)
"Super comfy bed breakfast wasnt bad lots of options"
United States
Cassandra
The price is 2.717.140 ₫
3.043.197 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Home2 Suites by Hilton Des Moines at Drake University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Greater South Side

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious hotel lobby with a central bar, seating area, and a ceiling fan.
Hampton Inn Des Moines-Airport
2.5 star property
8.8
Excellent
1,001 reviews
View
A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.
Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
8.6
Excellent
1,818 reviews
View
A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.
Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
8.4
Very good
727 reviews
View
A reception desk with a sign reading "AmericInn" and a clock on the wall.
AmericInn by Wyndham Des Moines Airport
3.0 star property
8.0
Very good
1,017 reviews
View
Breakfast area
Quality Inn & Suites Des Moines Airport
2.5 star property
7.6
Good
1,000 reviews
View

Where to stay in Greater South Side

Find the best Greater South Side areas for the activities you enjoy most.
The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

A sign reading "Historic East Village" with a clear blue sky and clouds in the background.

Historic East Village

Historic East Village is known for its abundant dining options, and you can plan a trip to Wooly's and Iowa State Capitol Building while you're in town.

A city skyline at night with illuminated buildings and a prominent tower.
Photo by Ryan Brohm
Open Photo by Ryan Brohm

Court District

Travellers come to Court District for its abundant dining options, and you can see top attractions like Science Center of Iowa and Principal Park while you're in town.

The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.
Photo by Eric Mondres
Open Photo by Eric Mondres

Drake

While visiting Drake, you might make a stop by sights like Knapp Center and Des Moines Community Playhouse.

A paved road flanked by trees and bushes, leading into the distance.
Photo by Emily Ruschill
Open Photo by Emily Ruschill

Southwestern Hills

Though Southwestern Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gray’s Lake Park and Lauridsen Amphitheater.

Top Greater South Side Hotel Reviews

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

10/10 Excellent
"Great location, beautiful hotel, nice rooms."
Kelsey 1-night trip
Posted 2 hours ago
Hotel Fort Des Moines, Curio Collection by Hilton

Frequently asked questions

What's it like in Greater South Side?
Travellers are sure to enjoy a stay in Des Moines's Greater South Side neighbourhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.
How many hotels can I expect to find in Greater South Side?
With 17 Expedia hotels and other accommodation options in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.
If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Greater South Side.
What is there to do around this Des Moines neighbourhood?
Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.