Uptown - Upper Duval Travel Guide

Key West

Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
South Beach which includes a sandy beach and a coastal town as well as a large group of people
South Beach featuring swimming, a luxury hotel or resort and a sandy beach
Key West Butterfly and Nature Conservatory showing signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(39 reviews)

You can find out about the history of Key West with a stop at Southernmost Point. Discover the area's lively bars and its lively festivals.

Southernmost Point
South Beach

South Beach

4.5/5(8 reviews)

If a restful holiday is part of your travel plans, South Beach might be the perfect place to visit during your trip to Key West. Stroll along the seaside or discover the area's sunsets.

South Beach
Key West Butterfly and Nature Conservatory showing animals, food and zoo animals

Key West Butterfly and Nature Conservatory

4.5/5(10 reviews)

Enjoy an outing to Key West Butterfly and Nature Conservatory during your stay in Key West. Amble around the area's seaside or seek out the cycling trails.

Key West Butterfly and Nature Conservatory

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
Fully refundable
The price is 4.672.111 ₫ per night from 13 Oct to 14 Oct
4.672.111 ₫
7.039.273 ₫ total
13 Oct - 14 Oct
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the bar in their reviews. ...
8.6/10 Excellent! (2,777 reviews)
"Our concierge was amazing! Very attentive and accommodating."

Reviewed on 25 Sept 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street, Key West, FL
The price is 5.354.990 ₫ per night from 2 Oct to 3 Oct
5.354.990 ₫
7.609.385 ₫ total
2 Oct - 3 Oct
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,013 reviews)
"Great staff, view and food!"

Reviewed on 24 Sept 2025

The Reach Key West, Curio Collection by Hilton
Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
The price is 3.305.559 ₫ per night from 28 Sept to 29 Sept
3.305.559 ₫
4.461.864 ₫ total
28 Sept - 29 Sept
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and a 24-hour front desk. Our guests praise the breakfast and the pool in their reviews. ...
8.6/10 Excellent! (1,186 reviews)
"The room was nice, & the area was fairly good. Near the Southernmost Point marker. Only downside was the water pressure was pretty weak."

Reviewed on 22 Sept 2025

Southwinds Motel
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street, Key West, FL
The price is 2.351.113 ₫ per night from 28 Sept to 29 Sept
2.351.113 ₫
3.833.504 ₫ total
28 Sept - 29 Sept
includes taxes & fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.2/10 Very Good! (1,177 reviews)
"Place was wonderful and very clean ! Walkable to several restaurants and Duval street was right there along with the Southernmost point ! Highly recommended!"

Reviewed on 24 Sept 2025

The Southernmost Inn - Adults Only
Santa Maria Suites

Santa Maria Suites

4 out of 5
1401 Simonton St, Key West, FL
The price is 6.499.903 ₫ per night from 28 Sept to 29 Sept
6.499.903 ₫
8.501.156 ₫ total
28 Sept - 29 Sept
includes taxes & fees
Stay at this 4-star resort in Key West. Enjoy free Wi-Fi, 2 outdoor pools and a fitness centre. Our guests praise the pool and the helpful staff in their reviews. ...
9.6/10 Exceptional! (1,007 reviews)
"The suite we stayed in was just like the pictures. I would stay there again the next time I go to the keys. Karen"

Reviewed on 21 Sept 2025

Santa Maria Suites
Kona Kai Oasis

Kona Kai Oasis

3 out of 5
630 South Street, Key West, FL
Stay at this 3-star guesthouse in Key West. Enjoy free Wi-Fi, free parking and a garden. Our guests praise the helpful staff in their reviews. Popular attractions ...
8/10 Very Good! (556 reviews)
"Not many towels and the fridge was dirty"

Reviewed on 6 Sept 2025

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Kona Kai Oasis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.

Old Town Key West
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Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
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Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
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White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Saint Mary Star of the Sea.

White Street Gallery District

Uptown - Upper Duval Travel Guide

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