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Check availability on Lake City Business Hotels

Our top choices for Lake City business-friendly hotels

Exterior
The Inn at the Crossroads

The Inn at the Crossroads

2.0 star property
Lake City
9.4 out of 10, Exceptional, (826)
"Awesome hotel stay "
United States
Jerry
The price is 3.535.144 ₫
3.959.362 ₫ total
includes taxes & fees
12 Dec - 13 Dec
The Inn at the Crossroads
Lobby
Quality Inn & Suites Lake City

Quality Inn & Suites Lake City

2.5 star property
Lake City
7.0 out of 10, Good, (165)
"Good for the weekend. "
United States
Amber
The price is 2.583.740 ₫
2.893.788 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn & Suites Lake City
Property entrance
Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City

2.0 star property
Lake City
6.4 out of 10, (241)
"Overall good stay for 1 night. "
United States
April
The price is 2.576.886 ₫
2.886.113 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Days Inn by Wyndham Lake City
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1162)
"Enjoyed our stay there. "
United States
Cathy
The price is 2.667.326 ₫
2.987.405 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Florence Center Area
Desk, iron/ironing board, free WiFi, bed sheets
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
Florence
6.8 out of 10, (1001)
"Clean rooms and wonderful staff "
United States
Rita
The price is 1.634.940 ₫
1.831.133 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Days Inn by Wyndham Florence Near Civic Center
Reception
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 star property
Florence
9.0 out of 10, Wonderful, (813)
"Very friendly and responsive staff. Very clean and comfortable room. Would definitely stay there again when we pass this way. "
United States
Maggie
The price is 2.700.288 ₫
3.024.323 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Florence Center
Reception
Hotel O Deluxe Inn Kingstree Sc Hwy 52

Hotel O Deluxe Inn Kingstree Sc Hwy 52

2.5 star property
Kingstree
2.0 out of 10, (2)
"As soon as we walked it several roaches crawled across our floor. Went to front desk and nobody answered. The furniture was also broken and damaged. And the shower was horrible. Hotel looks nothing like the photos. WILL NOT BE BOOKING AGAIN!!"
United States
Aprel
The price is 1.977.150 ₫
2.379.169 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hotel O Deluxe Inn Kingstree Sc Hwy 52
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
Florence
9.0 out of 10, Wonderful, (547)
"Good breakfast and room service "
United States
Indira
The price is 2.826.006 ₫
3.165.127 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Fairfield Inn & Suites by Marriott Florence I-20
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property
Florence
7.8 out of 10, Good, (1254)
"Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. "
United States
Tim
The price is 2.135.058 ₫
2.391.265 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Quality Inn & Suites Florence Civic Center
Exterior
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3.0 star property
Florence
9.0 out of 10, Wonderful, (701)
"Good stay, great staff"
United States
James
The price is 2.615.110 ₫
2.928.923 ₫ total
includes taxes & fees
14 Dec - 15 Dec
TownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lake City Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in Lake City cost?
You can expect to pay between 1.831.133 ₫ and 3.959.362 ₫ per night for business-friendly hotels in Lake City. Top deals on stays that are suitable for work-related guests as just a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Lake City?
Many corporate travellers recommend The Inn at the Crossroads. This 2-stars stay offers amenities such as al fresco dining and an outdoor entertainment area. Quality Inn & Suites is also popular. It has a 2.5-stars rating and conveniences like blackout curtains and complimentary breakfast. You'll have your pick of multiple business-friendly hotels in Lake City that have a total average guest review rating of 7.5.
How many business-friendly hotels are there in Lake City?
You can choose from 2 business-friendly hotels in Lake City. Whether you're searching for conveniences like meeting rooms or dependable WiFi, trust Expedia to help you find the ideal space to get the job done.
Why book your business-friendly hotel in Lake City with Expedia?
With top amenities like meeting rooms, 24-hour room service and free WiFi, our business-friendly accommodation come with everything you'll need to get the job done — and then chill! Enter your destination and preferred travel dates and we'll help you plan the rest.
How can I find cheap business-friendly hotels in Lake City?
Expedia can help you narrow down your search for cheap business-friendly hotels in Lake City. Look for the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like included breakfast and free WiFi. You can also choose your budget and hotel star rating to keep costs within your price range.
What is there to do in Lake City near my business-friendly hotel?
After you've settled into your hotel, venture out and discover the fun things Lake City has on offer. Moore Farms Botanical Garden is a top attraction to add to your travel itinerary.