The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Lester E. Cox Medical Center South hotels

A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.

A business center with two computers, a printer, and a lamp. There are signs indicating the business center is available 24 hours and providing emergency and front desk contact information.

A gym with various exercise machines, a clock, and a motivational sign.

The exterior of Hampton Inn with a clear sign, a welcome sign, and a clearance height sign.

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

2.642.358 ₫

2.999.340 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern hotel with a dark facade, multiple windows, and an American flag.

A modern living room with a sectional sofa, a coffee table, and yellow armchairs. There is a dining area with a table and chairs in the background.

A modern hotel lobby with a bar, seating area, kitchen, and a TV.

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Aaron

3.705.486 ₫

4.206.098 ₫ total

includes taxes & fees

31 Oct - 1 Nov

A spacious living area with large windows, a bar, and modern furniture.

A modern kitchen with a bar area, featuring a large TV, wooden shelves, and bar stools.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

A spacious kitchen with a large island, ample seating, and a view of the cityscape through large windows.

3. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Nathaniel

3.872.063 ₫

4.395.179 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A modern hotel room with a sofa, armchair, and a dining area with a kitchen in the background.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

A spacious lobby with a pool, comfortable seating, and a reception desk.

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

3.066.466 ₫

3.480.745 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

An outdoor patio with wicker furniture, a round table, and a grill area.

A buffet setup with various food items, a clock, and a coffee machine.

A hotel room with a desk, chair, TV, fireplace, bed, and a small dining area.

5. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Jacob

3.070.364 ₫

3.485.171 ₫ total

includes taxes & fees

19 Oct - 20 Oct

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

A lobby with a fireplace, large windows, and a view of the outdoors.

An indoor swimming pool with clear water, surrounded by a tiled floor and a glass wall.

A spacious hotel lobby with high ceilings, large windows, and a central seating area with tables and chairs.

6. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

daryl

3.153.782 ₫

3.612.973 ₫ total

includes taxes & fees

31 Oct - 1 Nov

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A hotel reception area with a counter displaying various alcohol bottles, a menu board, and artwork on the walls.

An indoor swimming pool with a tiled floor, a pool ladder, and a glass door leading to another room.

A compact hotel room with a sofa, a small table, a TV, and a desk with a coffee machine.

7. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Denise

2.307.646 ₫

2.667.195 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A modern living room with a fireplace, a sofa, a TV, and a staircase leading to a bedroom.

A kitchen area with a coffee machine, a buffet setup, and a dining table with chairs.

A spacious living area with a sofa, a ceiling fan, a staircase, and a kitchen area.

8. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Arthur

2.315.442 ₫

2.628.258 ₫ total

includes taxes & fees

12 Oct - 13 Oct

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and a view of the outdoors.

A modern living room with blue sofas, a stone accent wall, and a bookshelf.

A hotel room with a large bed, a wooden nightstand with a phone, two wall-mounted lamps, and a window with curtains.

A Comfort Inn hotel with a modern facade, a covered entrance, and a parking lot.

9. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

2.658.210 ₫

3.017.334 ₫ total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A hotel with a prominent sign, a covered parking area, and a well-lit entrance.

A spacious indoor dining area with multiple round tables and chairs, large windows, and a modern staircase.

A hotel room with two beds, a desk with a chair, a flat-screen TV, and a large window with curtains.

10. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

William

2.428.745 ₫

2.756.869 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, a staircase, and a seating area.

A hotel room with a bed, a chair, a nightstand with a lamp, and framed pictures on the wall.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

A modern hotel lobby with a sofa, armchairs, a coffee table, and a staircase.

11. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Dina

2.078.700 ₫

2.359.532 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

A hotel with a prominent sign for 'extended stay America' and a parking lot with several cars.

A compact kitchenette with white cabinets, a sink, a microwave, and a refrigerator.

12. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

1.870.804 ₫

2.123.398 ₫ total

includes taxes & fees

7 Oct - 8 Oct

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

A gym with exercise equipment, a treadmill, and a wall mural of athletes.

13. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Amanda

2.058.690 ₫

2.336.819 ₫ total

includes taxes & fees

29 Oct - 30 Oct

A modern hotel room with a large bed, a desk with a sink, and a view of the cityscape through large windows.

A rooftop lounge with wooden flooring, various seating options including sofas and chairs, a round table, and potted plants.

A modern kitchen with a large island, bar stools, a window with a city view, and pendant lighting.

A modern building with a prominent V-shaped entrance and large glass windows.

14. Hotel Vandivort

Downtown Springfield, 6.8 km from Lester E. Cox Medical Center South

George

4.395.701 ₫

5.012.892 ₫ total

includes taxes & fees

6 Oct - 7 Oct

A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A conference room with rows of tables and chairs, a flat-screen TV on the wall, and a door in the background.

A gym with treadmills, weight machines, and exercise mats.

15. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

2.962.518 ₫

3.362.978 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

An indoor swimming pool with a clear water line, surrounded by lounge chairs and tables.

A hotel with a clear entrance, a covered waiting area, and a parking lot.

A hotel lobby with a large bar area, seating, a fireplace, and framed pictures on the walls.

16. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Donna Sue

2.876.761 ₫

3.265.410 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

A modern kitchen with wooden cabinets, a countertop with various kitchen items, and a wall-mounted shelf with decorative objects.

An outdoor patio area with a stone wall, wooden pergola, and seating arrangements including a sofa and chairs.

A modern hotel room with a dark grey sofa, a wooden side table, a desk with a chair, and two abstract paintings on the walls.

17. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Amanda

2.962.518 ₫

3.480.735 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A spa area with a hot tub, a pool, and a seating area with tables and chairs.

A Drury Inn & Suites hotel with a modern design, featuring a prominent entrance and stone pillars.

A modern kitchen with a long counter, wooden cabinets, and a backsplash.

18. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Deanna

2.910.284 ₫

3.332.565 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

A modern hotel room with a stone accent wall, a flat-screen TV, a fireplace, a sofa, a dining area, and a patterned carpet.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a parking lot.

A modern living room with a wooden dining table, comfortable seating, a stone accent wall, and a large window.

19. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Kristal

2.721.359 ₫

3.152.103 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with a stone wall, a fire pit, and outdoor seating.

A modern hotel with a prominent "HOME 2" sign, a covered entrance, and a parking area with a handicap parking space.

A modern restaurant with a long counter, multiple seating areas, and a variety of tableware displayed on shelves.

A hotel room with a desk, two beds, a sofa, a TV, and a large window.

20. Home2 Suites by Hilton Springfield North

Parkwood, 11.4 km from Lester E. Cox Medical Center South

Vicky

3.729.135 ₫

4.270.233 ₫ total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 717 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 564 reviews	View
Element by Marriott Springfield South	9.2 Wonderful 155 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 434 reviews	View
Residence Inn by Marriott Springfield	9.0 Wonderful 1,001 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Comfort Inn South - Springfield

8/10 Good

"Rooms were clean and refreshed. closet door latch was broke, and toilet wobbled. Notified desk at end of stay, and stated they would be handled. :-)"

Homewood Suites by Hilton Springfield Medical District

8/10 Good

"Good"

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"This is gonna be our go to stay in Springfield. The staff was friendly. The place was very clean. Our room was very clean. We had a standard two queen room that was huge. The bed was super comfortable. The pool area and hot tub was super clean and very nice and their breakfast was really good."

Element by Marriott Springfield South

10/10 Excellent

"Great place to stay"

The Bradford Hotel, an Ascend Collection Hotel

8/10 Good

"The staff is friendly and responsive to issues with the room. The room was clean and beds were comfortable. The breakfast was only adequate. They did not restock the breakfast food efficiently, and the eggs and gravy reminded me of the food at summer camp! The hotel needs to keep up with maintenance. Items noted were a broken 1st floor ice machine, the door to the room has missing weatherstripping. The bathroom sink was slow and the shower head was partially clogged. The door swing bar guard that uses a solid, hinged U-shaped metal bar was installed improperly and would not secure the door."

Residence Inn by Marriott Springfield

10/10 Excellent

"Great! I love staying with the Marriotts. Always my first choice."

Sleep Inn Springfield South I60 near Medical District

10/10 Excellent

"The staff was so friendly and the breakfast was great. Very convenient location for travelers - places to eat and gas up so nearby."

Lamplighter Inn & Suites - South

10/10 Excellent

"The staff was wonderful due to a family emergency I had to check in at different hours for several days over a couple weeks time and they were all great. The are in the middle of redoing the older rooms but everything is still clean and out of they way. You can see the construction but it never was loud or disturbing to us. If I had any questions everyone was willing to help. I will definitely be staying again"

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travellers like for its sporting events and opera houses. If you're looking for a convenient place to stay, take a look at the 19 hotels and other accommodation options you'll find within a mile.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 19 hotels and other accommodation options within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best deals available near Lester E. Cox Medical Center South.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Element by Marriott Springfield South

4. Candlewood Suites Springfield-Medical District

5. Residence Inn by Marriott Springfield

6. Hilton Garden Inn Springfield, MO

7. La Quinta Inn & Suites by Wyndham Springfield South

8. MainStay Suites Springfield South - Battlefield Rd

9. Comfort Inn South - Springfield

10. The Bradford Hotel, an Ascend Collection Hotel

11. Sleep Inn Springfield South I60 near Medical District

12. Extended Stay America Select Suites Springfield South

13. Clarion Pointe Springfield Southeast

14. Hotel Vandivort

15. Holiday Inn Express & Suites Springfield North by IHG

16. Hampton Inn Springfield-Southeast

17. SpringHill Suites by Marriott Springfield North

18. Drury Inn & Suites Springfield, MO

19. Fairfield Inn & Suites by Marriott Springfield North

20. Home2 Suites by Hilton Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Comfort Inn South - Springfield

Homewood Suites by Hilton Springfield Medical District

Holiday Inn Express and Suites Springfield Medical District by IHG

Element by Marriott Springfield South

The Bradford Hotel, an Ascend Collection Hotel

Residence Inn by Marriott Springfield

Sleep Inn Springfield South I60 near Medical District

Lamplighter Inn & Suites - South

Frequently asked questions

Search Hotels Near Lester E. Cox Medical Center South, Springfield

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Element by Marriott Springfield South

4. Candlewood Suites Springfield-Medical District

5. Residence Inn by Marriott Springfield

6. Hilton Garden Inn Springfield, MO

7. La Quinta Inn & Suites by Wyndham Springfield South

8. MainStay Suites Springfield South - Battlefield Rd

9. Comfort Inn South - Springfield

10. The Bradford Hotel, an Ascend Collection Hotel

11. Sleep Inn Springfield South I60 near Medical District

12. Extended Stay America Select Suites Springfield South

13. Clarion Pointe Springfield Southeast

14. Hotel Vandivort

15. Holiday Inn Express & Suites Springfield North by IHG

16. Hampton Inn Springfield-Southeast

17. SpringHill Suites by Marriott Springfield North

18. Drury Inn & Suites Springfield, MO

19. Fairfield Inn & Suites by Marriott Springfield North

20. Home2 Suites by Hilton Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Comfort Inn South - Springfield

Homewood Suites by Hilton Springfield Medical District

Holiday Inn Express and Suites Springfield Medical District by IHG

Element by Marriott Springfield South

The Bradford Hotel, an Ascend Collection Hotel

Residence Inn by Marriott Springfield

Sleep Inn Springfield South I60 near Medical District

Lamplighter Inn & Suites - South

Frequently asked questions