Lower Matecumbe Key Holidays

Book a Hotel + Flight or Car together to unlock savings

Top hotels in Lower Matecumbe Key

Caloosa Cove Resort by CoolVacay

Caloosa Cove Resort by CoolVacay

3 out of 5
73801 Overseas Hwy Islamorada FL
9.8/10 Exceptional! (8 reviews)
"Great location, we will return"

Reviewed on 9 Jul 2026

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Caloosa Cove Resort by CoolVacay
Matecumbe Resort

Matecumbe Resort

2 out of 5
76261 Overseas Hwy Islamorada FL
9/10 Wonderful! (149 reviews)
"All good! People need to understand the ocean seaweed and smell is uncontrollable by the hotel. We lived that they had kayaks to take out, beach volleyball, hammocks and a kid playground; all that we adults could sit outside the room and supervise the kids. Also pool was nice and clean. Will be back ..."

Reviewed on 6 Jul 2026

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Matecumbe Resort
Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
Fully refundableReserve now, pay when you stay
The price is 6.274.945 ₫ per night from 16 Jul to 17 Jul
6.274.945 ₫
8.979.341 ₫ total
16 Jul - 17 Jul
includes taxes & fees
9.2/10 Wonderful! (1,350 reviews)
"Visited in July and the stench of the seaweed was terrible for a luxury resort! Made the pool and outside dining basically unusable. Resorts in Marathon and Key West both cleared beaches daily to decrease the stench, which was very much appreciated!"

Reviewed on 14 Jul 2026

Cheeca Lodge & Spa
See all 2,086 properties in Lower Matecumbe Key
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Lower Matecumbe Key attractions

Anne's Beach

7.8/10 (597 reviews)
If a restful holiday is part of your travel plans, Anne's Beach might be the perfect place to visit during your trip to Islamorada.
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Frequently asked questions

How much does a Lower Matecumbe Key holiday package cost?
Custom build your Lower Matecumbe Key holiday package from an affordable . Choose from any combination of flights, hotels and rental cars to put together the escape you've long been dreaming about. Be sure to add on a few experiences or tours!
How do I get a cheap travel package to Lower Matecumbe Key?
You'll save big if you combine your hotels, car rentals and flights into a Lower Matecumbe Key travel package. Sometimes cheap means fewer options. But that's not the case with Expedia. We offer more than 550 partner airlines and 1null000null000 hotels worldwide, so you'll always have plenty of variety to choose from. Want to save even more? Add some exciting activities to your package deal to unlock even more bargains! After all, travel is about more than just getting to your destination.
How far in advance should I book my Lower Matecumbe Key holiday?
Reward yourself with the biggest variety at the cheapest prices by booking your trip to Lower Matecumbe Key early. Airlines typically sell flight tickets around a year before departure, so secure your spot as soon as possible. Having said that, Expedia is committed to giving you the best deals around, so there's never a bad time to book your dream holiday!
What does an Expedia Lower Matecumbe Key travel package include?
Flights, hotels and a shiny set of wheels for your road trip adventures. Simply pick and choose your preferred bundle and get access to incredible deals. Once you've made your booking, add on a couple of tours and experiences and watch your savings grow. When it comes to crafting your Lower Matecumbe Key getaway, you're the one in control!
What should I know before booking a Lower Matecumbe Key travel package?
You'll save big with an Expedia travel package. Bundle your flights, rental cars and hotels and enjoy fantastic discounts. You're not restricted to hotels, though. We have island resorts, cabins in the mountains and even treehouses and ranches!
Can I choose my airline with a Lower Matecumbe Key Expedia holiday package?
With a holiday package, you're the boss. Whether you're hoping to fly to Lower Matecumbe Key in economy or business class, simply choose from the available airline options. Expedia has access to more than 550 airline partners globally.
If I'm not able to travel, can I cancel my Lower Matecumbe Key holiday package?
Certainly, and we're here to help. You may be able to cancel or change your Lower Matecumbe Key holiday package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company for older bookings. If your travel plans suddenly change, look up our Customer Service Portal for more information.

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