Madre de Dios Region Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by James Pinkney

Top destinations in Madre de Dios Region

FlightsFlightsHotelsHotels

Tambopata

Tambopata
FlightsFlightsHotelsHotels

Manu

Manu

Top hotels in Madre de Dios Region

Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429, Tambopata, Madre de Dios
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (17 reviews)
"Great stay, friendly owners and staff."

Reviewed on 22 Jun 2025

Get rates
Libelula Hotel
Dmilez Hotel

Dmilez Hotel

2.5 out of 5
Psj. Tupac Amaru, Mz. E, Lot 6, A.H.8 de Octubre, Tambopata, Madre de Dios
7.2/10 Good! (26 reviews)
"Air conditioning was cold and very good. Pool is nice. Staff goes above and beyond. Place is clean, Bed is comfortable."

Reviewed on 11 Sept 2025

Get rates
Dmilez Hotel
IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo, Tambopata, Madre de Dios
The price is 5.489.184 ₫ per night from 4 Oct to 5 Oct
5.489.184 ₫
5.763.643 ₫ total
4 Oct - 5 Oct
9/10 Wonderful! (6 reviews)
"Half an hour a at from Puerto Maldonado by boat , the place is lovely, with river view and a feel of the jungle without venturing too far. We felt like we got a good insight into the area, with included excursions on the river and into the jungle. Our guide Yuri, who was with us throughout, was very ..."

Reviewed on 23 Sept 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
See all 55 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Madre de Dios Region holiday package cost?
Choose from any combination of hotels, flights and car rentals, and you can be holidaying in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region holiday packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1null000null000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cosy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region holiday?
Reward yourself with the biggest variety and the lowest prices by booking your holiday to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream holiday!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favourite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cosy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia holiday package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region holiday package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.

Popular places to visit

Manu National Park

Explore the great outdoors at Manu National Park, a lovely green space in Manu.

Manu National Park

Francisco Bolognesi Square

Francisco Bolognesi Square is just one of the places to see in Puerto Maldonado, so why not enjoy the other things to explore during your travels? Wander the riverfront and forests while you're in the area.

Francisco Bolognesi Square

Island of Monkeys

Commune with nature and explore the great outdoors at Island of Monkeys during your travels in Las Piedras. Wander the riverfront and rainforest while you're in the area.

Island of Monkeys