Madre de Dios Region Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by nevin xavier

Top destinations in Madre de Dios Region

A river winding through a dense forest under a cloudy sky.

Tambopata

Tambopata
A calm river with wooden docks and lush greenery in the background.

Manu

Manu

Where to stay in Madre de Dios Region

Find the best Madre de Dios Region areas for the activities you enjoy most.Learn more about Madre de Dios Region
Learn more about Madre de Dios Region

Chapajal

While Chapajal isn't home to many top sights, Puerto Maldonado Plaza de Armas and Puerto Maldonado Obelisk are some notable places to visit nearby.

Top hotels in Madre de Dios Region

IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

Tambopata KM. 7 Otr. Carretera Bajo Tambopata Madre de Dios
4.197.375 ₫
4.407.244 ₫ total
14 Aug - 15 Aug
9.2/10 Wonderful! (19 reviews)
"We had an amazing time. Staff as veery helpful organizing customized tours for our family. The menu at the restaurant is excellent. Breakfast was inclusive and good choices. Lunch and dinner had great options. A perfect retreat exploring the Amazon."

Reviewed on 2 Aug 2026

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Libelula Hotel

Libelula Hotel

Jr Puno No. 429 Tambopata Madre de Dios
Fully refundableReserve now, pay when you stay
1.086.750 ₫
1.086.750 ₫ total
8 Aug - 9 Aug
8.8/10 Excellent! (32 reviews)
"We really enjoyed our stay after our jungle excursion. The staff were very friendly and helped us find fun things to do and amazing places to eat. They spoke English and offered great suggestions. We were so grateful to get back to a clean room, hot water and wifi access."

Reviewed on 28 Jul 2026

Libelula Hotel
 Andean Wings Sotupa Eco Lodge

Andean Wings Sotupa Eco Lodge

Carretera Tambopata Km 11,5 Tambopata Madre de Dios
6.973.616 ₫
7.670.978 ₫ total
8 Aug - 9 Aug
Andean Wings Sotupa Eco Lodge
See all 60 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Madre de Dios Region holiday package cost?
Choose from any combination of hotels, flights and car rentals, and you can be holidaying in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region holiday packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1null000null000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cosy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region holiday?
Reward yourself with the biggest variety and the lowest prices by booking your holiday to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream holiday!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favourite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cosy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia holiday package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region holiday package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.

Stay near popular Madre de Dios Region attractions

Puerto Maldonado Plaza de Armas

8.2/10 (22 reviews)
You can find out about the history of Puerto Maldonado with a trip to Puerto Maldonado Plaza de Armas. Wander the riverfront and forests while you're in the area.
See properties

Francisco Bolognesi Square

9.0/10 (7 reviews)
Francisco Bolognesi Square is just one of the places to see in Puerto Maldonado, so why not enjoy the other things to explore during your travels? Wander the riverfront and forests while you're in the area.
See properties

Manu National Park

Explore the great outdoors at Manu National Park, a lovely green space in Manu.
See properties

Island of Monkeys

8.6/10 (11 reviews)
Commune with nature and explore the great outdoors at Island of Monkeys during your travels in Las Piedras. Wander the riverfront and rainforest while you're in the area.
See properties

Lake Sandoval

9.8/10 (31 reviews)
Commune with nature and explore the great outdoors at Lake Sandoval during your travels in Tambopata. Wander the riverfront and rainforest while you're in the area.
See properties

Puerto Maldonado Obelisk

8.4/10 (9 reviews)
Find out about the history of Puerto Maldonado with a stop at Puerto Maldonado Obelisk. Wander the riverfront and forests while you're in the area.
See properties

Parque Nacional Manu

You can find out about the history of Manu with a stop at Parque Nacional Manu. While you're in the area, wander around the parks.
See properties

Explore a world of travel with Expedia