Search Hotels in Main Street, Ann Arbor

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Dec - 17 Dec
Tomorrow
17 Dec - 18 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street hotels

Property amenity
Courtyard by Marriott Detroit Brighton

Courtyard by Marriott Detroit Brighton

Courtyard by Marriott Detroit Brighton
3.0 star property
30.2 km from Main Street
8.6 out of 10, Excellent, (508)
"Very nice place to stay. Clean. The bed was so comfortable "
United States
Mike
The price is 2.446.551 ₫
2.715.671 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott Detroit Brighton
Superior Room, 1 King Bed, Non Smoking | Desk, blackout curtains, free cots/infant beds, free WiFi
Red Roof Inn Detroit - Plymouth/ Canton

Red Roof Inn Detroit - Plymouth/ Canton

Red Roof Inn Detroit - Plymouth/ Canton
2.0 star property
27.5 km from Main Street
7.0 out of 10, Good, (1001)
"Staff was very friendly and helpful!"
United States
Michael
The price is 1.467.694 ₫
1.636.479 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Red Roof Inn Detroit - Plymouth/ Canton
In-room safe, desk, iron/ironing board, free cots/infant beds
Holiday Inn Express & Suites Brighton South - US 23 by IHG

Holiday Inn Express & Suites Brighton South - US 23 by IHG

Holiday Inn Express & Suites Brighton South - US 23 by IHG
2.5 star property
24.4 km from Main Street
8.6 out of 10, Excellent, (824)
"Wonderful breakfast and staff "
United States
Gerald
The price is 2.104.560 ₫
2.336.062 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Express & Suites Brighton South - US 23 by IHG
Indoor pool
Comfort Inn Chelsea

Comfort Inn Chelsea

Comfort Inn Chelsea
2.5 star property
23 km from Main Street
7.8 out of 10, Good, (742)
"The room was clean and the check in staff was very forthcoming with what wasn't available prior to starting the check in process. "
United States
Roland
The price is 1.633.665 ₫
1.813.368 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Comfort Inn Chelsea
Lobby
Homewood Suites by Hilton Brighton

Homewood Suites by Hilton Brighton

Homewood Suites by Hilton Brighton
3.0 star property
29.2 km from Main Street
8.4 out of 10, Very good, (750)
"Clean quiet rooms and friendly staff."
United States
James
The price is 1.873.058 ₫
2.079.094 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Homewood Suites by Hilton Brighton
Front of property
Your Motel

Your Motel

Your Motel
2.5 star property
13.3 km from Main Street
8.4 out of 10, Very good, (70)
"New carpeting only update to very dated and old property!! Staff very friendly and accommodating."
United States
Micki
The price is 2.249.248 ₫
2.496.665 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Your Motel
View from property
Fairfield Inn & Suites by Marriott Ann Arbor Ypsilanti

Fairfield Inn & Suites by Marriott Ann Arbor Ypsilanti

Fairfield Inn & Suites by Marriott Ann Arbor Ypsilanti
2.5 star property
12.3 km from Main Street
9.2 out of 10, Wonderful, (694)
"Everyone was friendly, place was clean and easy to find. "
United States
Heather
The price is 2.578.086 ₫
2.861.676 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Ann Arbor Ypsilanti
Indoor pool, open 7:00 AM to 10:00 PM, pool loungers
Spark by Hilton Plymouth

Spark by Hilton Plymouth

Spark by Hilton Plymouth
3.0 star property
26.8 km from Main Street
8.4 out of 10, Very good, (1002)
"The hotel staff is great, they let me check in early, and the breakfast is a nice perk."
United States
Ryan
The price is 2.293.970 ₫
2.557.777 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Spark by Hilton Plymouth
Bar (on property)
Hilton Garden Inn Plymouth

Hilton Garden Inn Plymouth

Hilton Garden Inn Plymouth
3.0 star property
25 km from Main Street
8.6 out of 10, Excellent, (937)
"Staff were so nice, room was clean and big."
United States
Natasha
The price is 2.451.489 ₫
2.733.411 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Plymouth
Indoor pool, pool loungers
Candlewood Suites Brighton by IHG

Candlewood Suites Brighton by IHG

Candlewood Suites Brighton by IHG
2.5 star property
29.2 km from Main Street
9.4 out of 10, Exceptional, (522)
"Great atmosphere "
United States
Guy
The price is 2.262.402 ₫
2.511.266 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Candlewood Suites Brighton by IHG
Presidential Suite, 1 King Bed with Sofa bed, Non Smoking | Living area | Flat-screen TV, video game console, pay films
Wingate by Wyndham Brighton

Wingate by Wyndham Brighton

Wingate by Wyndham Brighton
2.5 star property
29.7 km from Main Street
7.8 out of 10, Good, (1007)
"Clean rooms, kind staff & clean hotel. "
United States
Jessica
The price is 1.542.906 ₫
1.712.626 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Wingate by Wyndham Brighton
Indoor pool
Hampton Inn Brighton

Hampton Inn Brighton

Hampton Inn Brighton
2.5 star property
29.4 km from Main Street
8.8 out of 10, Excellent, (777)
"Clean room staff great and great food."
United States
Kathleen L
The price is 2.293.970 ₫
2.546.307 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn Brighton
Property amenity
Holiday Inn Express & Suites Brighton by IHG

Holiday Inn Express & Suites Brighton by IHG

Holiday Inn Express & Suites Brighton by IHG
2.5 star property
29.5 km from Main Street
9.0 out of 10, Wonderful, (576)
"Great stay! Nice staff and very clean!"
Canada
Meera
The price is 2.604.393 ₫
2.890.876 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Express & Suites Brighton by IHG
Free daily self-service breakfast
Baymont by Wyndham Chelsea

Baymont by Wyndham Chelsea

Baymont by Wyndham Chelsea
2.5 star property
22.9 km from Main Street
7.8 out of 10, Good, (1000)
"Very friendly staff, comfortable beds and fee breakfast that has everything in minimal size "
Canada
Dani
The price is 1.990.125 ₫
2.209.039 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Baymont by Wyndham Chelsea
Terrace/patio
Home2 Suites by Hilton Northville Detroit

Home2 Suites by Hilton Northville Detroit

Home2 Suites by Hilton Northville Detroit
3.0 star property
23.1 km from Main Street
8.8 out of 10, Excellent, (193)
"Staff, room, everything great. Highly recommend this hotel."
United States
Ronald
The price is 2.567.037 ₫
2.862.247 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites by Hilton Northville Detroit
Exterior
Country Meadow inn

Country Meadow inn

Country Meadow inn
2.0 star property
23.7 km from Main Street
6.6 out of 10, (33)
"Its a great room. My only issue is the bathroom floor is a little slippery but i brought a bath mat from dollar tree. I usually do as so many hotel bathrooms have a slippery floor Very nice manager. I like this place"
Canada
Darlene
Country Meadow inn
Garden
Saint John's Resort

Saint John's Resort

Saint John's Resort
4.0 star property
25.7 km from Main Street
9.6 out of 10, Exceptional, (1007)
"Room was amazing, the staff was very friendly and helpful. "
United States
Theresa
The price is 5.934.596 ₫
7.785.294 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Saint John's Resort
Lobby lounge
The Vanguard Ann Arbor, Autograph Collection

The Vanguard Ann Arbor, Autograph Collection

The Vanguard Ann Arbor, Autograph Collection
4.0 star property
Old Fourth Ward, 1.1 km from Main Street
9.8 out of 10, Exceptional, (43)
"Excellent hotel, new, clean, great service, fantastic food and service."
United States
Peter
The price is 3.998.664 ₫
5.314.540 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Vanguard Ann Arbor, Autograph Collection
Meeting facility
Ann Arbor Marriott Ypsilanti at Eagle Crest

Ann Arbor Marriott Ypsilanti at Eagle Crest

Ann Arbor Marriott Ypsilanti at Eagle Crest
4.0 star property
12.8 km from Main Street
8.8 out of 10, Excellent, (567)
"Nice clean room"
United States
Joseph
The price is 2.893.770 ₫
3.212.084 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Ann Arbor Marriott Ypsilanti at Eagle Crest
Exterior
TownePlace Suites by Marriott Detroit Belleville

TownePlace Suites by Marriott Detroit Belleville

TownePlace Suites by Marriott Detroit Belleville
3.0 star property
22.2 km from Main Street
9.2 out of 10, Wonderful, (335)
"This is my home away from home! I live the atmosphere and the staff!"
United States
Audrey
The price is 2.657.007 ₫
2.962.563 ₫ total
includes taxes & fees
21 Dec - 22 Dec
TownePlace Suites by Marriott Detroit Belleville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Main Street

Find the best Main Street areas for the activities you enjoy most.

South Central

If you're spending some time in South Central, Yost Ice Arena and Michigan Stadium are top sights worth seeing.

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Cobblestone Farm and Buhr Park are top sights worth seeing.

Hidden Valley

If you're spending some time in Hidden Valley, Varsity Tennis Center and University of Michigan Golf Course are top sights worth seeing.

Ann Arbor featuring a house

Downtown

If you're spending some time in Downtown, Ann Arbor Hands On Museum and Kempf House Museum are top sights worth seeing.

Burns Park

When in Burns Park, you can plan a visit to Yost Ice Arena and Exhibit Museum of Natural History at the University Of Michigan, some noteworthy sights in the nearby area.

Top Main Street Hotel Reviews

Home2 Suites By Hilton Ann Arbor South

Home2 Suites By Hilton Ann Arbor South

10/10 Excellent
"Very new and clean property "
REGINALDO 3-night trip
Posted 10 days ago
Home2 Suites By Hilton Ann Arbor South

Explore a world of travel with Expedia

Frequently asked questions

What is Main Street like?
Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.
If I need to cancel my hotel reservation in Main Street, will I receive a refund?
Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.
What is there to do around this Ann Arbor neighbourhood?
Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.