Main Street Cultural District

A large metal gate with a curved top, surrounded by trees and a building with large windows.
A street lined with parked cars, a mural, and various storefronts.
A red sign with yellow text that reads "WELCOME IOWA STATE STUDENTS" and a gold seal.
A street with brick buildings, a black awning, and a sign for 'Men's Shoes'.
A red minivan parked on a street with a brick building in the background.


Stay near popular Main Street Cultural District attractions


Top Hotel Deals

Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive Ames IA
Gateway Hotel and Conference Center at Iowa State University
Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites

2.5 out of 5
2500 University Blvd. Ames IA
Best Western Plus University Park Inn & Suites
Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

2.5 out of 5
603 South 16th Street Ames IA
Comfort Inn and Suites Ames near ISU Campus
Spark by Hilton Ames

Spark by Hilton Ames

3 out of 5
2609 University Blvd Ames IA
Spark by Hilton Ames
GrandStay Hotel & Suites

GrandStay Hotel & Suites

2.5 out of 5
1606 S Kellogg Ave Ames IA
GrandStay Hotel & Suites
SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames

2.5 out of 5
1810 SE 16TH STREET Ames IA
SpringHill Suites by Marriott Ames
Microtel Inn & Suites by Wyndham Ames

Microtel Inn & Suites by Wyndham Ames

2 out of 5
2216 Se 16th St Ames IA
Microtel Inn & Suites by Wyndham Ames
AmericInn by Wyndham Ames

AmericInn by Wyndham Ames

3 out of 5
2507 SE 16th St. Ames IA
AmericInn by Wyndham Ames
Home2 Suites By Hilton Ames

Home2 Suites By Hilton Ames

3 out of 5
2125 Isaac Newton Dr Ames IA
Home2 Suites By Hilton Ames
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.