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Check availability on Mayagüez Luxury Hotels

Our top choices for Mayagüez luxury hotels

Luxury Room | Frette Italian sheets, hypo-allergenic bedding, down duvets
Royal Isabela

Royal Isabela

Royal Isabela
4.5 star property
Isabela
9.6 out of 10, Exceptional, (162)
"Great resort! "
United States
Jodie
The price is 18.235.534 ₫
23.852.079 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Royal Isabela
Beach nearby, white sand, beach towels
Parguera Plaza Hotel - Adults Only

Parguera Plaza Hotel - Adults Only

Parguera Plaza Hotel - Adults Only
4.0 star property
Lajas
9.6 out of 10, Exceptional, (649)
"We had a good time and we are going back soon. Excellent staff and nice place to stay. "
United States
Magaly
The price is 3.956.497 ₫
4.312.582 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Parguera Plaza Hotel - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayagüez Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Mayagüez?
Use Expedia to arrange your flight to Mayagüez (MAZ-Eugenio María de Hostos) airport or Aguadilla (BQN-Rafael Hernandez) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a holiday, so we make it easy to get what you'd like to make your stay special. If you want a posh hotel that has fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Mayagüez has to offer. During your visit, you might want to enjoy the entertainment which Mayagüez is known for.
When can I expect good weather in Mayagüez?
Planning for the weather is a good way to make your trip to Mayagüez relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and September, with an average temperature of 28°C, while the coldest months are March and February, with an average of 25°C. Average annual precipitation for Mayagüez is 890 mm.
What's there to see and do in Mayagüez?
Take in some sights and attractions while you're in Mayagüez by visiting Plaza Colon, Mayagüez Mall and Mona Island. If you have some spare time during your trip, you might want to check out Yaguez Theater and Playa El Maní.