Search Hotels Near Medical City Frisco, Dallas

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
15 Dec - 16 Dec
Tomorrow
16 Dec - 17 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical City Frisco hotels

Exterior
Courtyard By Marriott Dallas Frisco

Courtyard By Marriott Dallas Frisco

Courtyard By Marriott Dallas Frisco
3.0 star property
0.7 km from Medical City Frisco
9.6 out of 10, Exceptional, (109)
"Excellent stay "
United States
Gary
The price is 3.735.594 ₫
4.397.856 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Courtyard By Marriott Dallas Frisco
Exterior
Holiday Inn Express & Suites Dallas-Frisco NW Toyota Stdm by IHG

Holiday Inn Express & Suites Dallas-Frisco NW Toyota Stdm by IHG

Holiday Inn Express & Suites Dallas-Frisco NW Toyota Stdm by IHG
2.5 star property
0.9 km from Medical City Frisco
9.0 out of 10, Wonderful, (1005)
"clean room and great staff. Breakfast was good as well"
United States
Jim
The price is 2.051.946 ₫
2.365.073 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Holiday Inn Express & Suites Dallas-Frisco NW Toyota Stdm by IHG
Restaurant
Hampton Inn & Suites Dallas/Frisco North-FieldhouseUSA

Hampton Inn & Suites Dallas/Frisco North-FieldhouseUSA

Hampton Inn & Suites Dallas/Frisco North-FieldhouseUSA
2.5 star property
1.4 km from Medical City Frisco
9.0 out of 10, Wonderful, (1001)
"Staff was very friendly upon arrival. Seamless check-in!"
United States
Marsha
The price is 2.293.970 ₫
2.644.030 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Dallas/Frisco North-FieldhouseUSA
Indoor pool
La Quinta Inn & Suites by Wyndham Dallas - Frisco Stadium

La Quinta Inn & Suites by Wyndham Dallas - Frisco Stadium

La Quinta Inn & Suites by Wyndham Dallas - Frisco Stadium
3.0 star property
1 km from Medical City Frisco
8.6 out of 10, Excellent, (1135)
"Great location, boutique like hotel, dog friendly "
United States
Kristy
The price is 1.990.125 ₫
2.293.818 ₫ total
includes taxes & fees
29 Dec - 30 Dec
La Quinta Inn & Suites by Wyndham Dallas - Frisco Stadium
Terrace/patio
Candlewood Suites Dallas-Frisco NW Toyota Ctr by IHG

Candlewood Suites Dallas-Frisco NW Toyota Ctr by IHG

Candlewood Suites Dallas-Frisco NW Toyota Ctr by IHG
2.5 star property
0.9 km from Medical City Frisco
8.6 out of 10, Excellent, (405)
"Great stay! Clean rooms in great condition and in a great location to attend events at Toyota Park"
Canada
Kristjan
The price is 2.078.253 ₫
2.395.252 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Candlewood Suites Dallas-Frisco NW Toyota Ctr by IHG
Lobby
Comfort Suites Frisco

Comfort Suites Frisco

Comfort Suites Frisco
2.5 star property
0.7 km from Medical City Frisco
8.4 out of 10, Very good, (1010)
"Staff was great, the room was clean and spacious. Location was tough due to the busy highway right outside my window. A bit too loud to get any real good sleep."
United States
Scott
The price is 2.107.191 ₫
2.428.749 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Comfort Suites Frisco
Outdoor pool, open 11:00 AM to 7:00 PM, pool loungers
Omni Frisco Hotel at The Star

Omni Frisco Hotel at The Star

Omni Frisco Hotel at The Star
4.0 star property
4.7 km from Medical City Frisco
9.4 out of 10, Exceptional, (1003)
"Great location, friendly staff and comfortable rooms"
United States
Jonathan
The price is 6.132.398 ₫
7.174.225 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Omni Frisco Hotel at The Star
Seasonal outdoor pool
HALL Park Hotel, Autograph Collection

HALL Park Hotel, Autograph Collection

HALL Park Hotel, Autograph Collection
4.0 star property
5 km from Medical City Frisco
9.6 out of 10, Exceptional, (119)
"Great stay. "
United States
Joshua
The price is 5.024.637 ₫
5.907.225 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
HALL Park Hotel, Autograph Collection
Lounge
AC Hotel by Marriott Dallas Frisco

AC Hotel by Marriott Dallas Frisco

AC Hotel by Marriott Dallas Frisco
3.5 star property
4.2 km from Medical City Frisco
9.0 out of 10, Wonderful, (502)
"Room was clean, friendly front desk and valley staff. Great place to stay. "
United States
Danielle
The price is 3.253.387 ₫
3.771.264 ₫ total
includes taxes & fees
28 Dec - 29 Dec
AC Hotel by Marriott Dallas Frisco
Lobby
Canopy by Hilton Dallas Frisco Station, TX

Canopy by Hilton Dallas Frisco Station, TX

Canopy by Hilton Dallas Frisco Station, TX
4.0 star property
4.1 km from Medical City Frisco
8.8 out of 10, Excellent, (863)
"No complaints whatsoever! We enjoyed our stay."
United States
Lateka
The price is 2.525.472 ₫
2.927.275 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Canopy by Hilton Dallas Frisco Station, TX
Exterior
Homewood Suites by Hilton Dallas-Frisco

Homewood Suites by Hilton Dallas-Frisco

Homewood Suites by Hilton Dallas-Frisco
3.0 star property
5.4 km from Medical City Frisco
9.6 out of 10, Exceptional, (1004)
"Loved our stay!"
United States
Carolina
The price is 2.925.338 ₫
3.371.744 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Homewood Suites by Hilton Dallas-Frisco
Property amenity
Drury Inn & Suites Dallas Frisco

Drury Inn & Suites Dallas Frisco

Drury Inn & Suites Dallas Frisco
3.0 star property
5.7 km from Medical City Frisco
9.6 out of 10, Exceptional, (1174)
"Always stay here when we have tournaments next door at Comerica Center, always a good stay and the breakfast is a plus!"
United States
Michelle
The price is 2.472.595 ₫
2.849.837 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Dallas Frisco
Exterior
Residence Inn by Marriott Dallas Frisco

Residence Inn by Marriott Dallas Frisco

Residence Inn by Marriott Dallas Frisco
3.0 star property
4.4 km from Medical City Frisco
8.8 out of 10, Excellent, (255)
"Room is nice, staff is amazing"
United States
Jacque
The price is 3.656.673 ₫
4.238.847 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Residence Inn by Marriott Dallas Frisco
Seasonal outdoor pool
Hotel Indigo Frisco by IHG

Hotel Indigo Frisco by IHG

Hotel Indigo Frisco by IHG
3.5 star property
5.7 km from Medical City Frisco
9.2 out of 10, Wonderful, (1005)
"Great stay! Nice staff, clean rooms!"
United States
Julia
The price is 2.657.007 ₫
3.062.466 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hotel Indigo Frisco by IHG
Reception
Hyatt Regency Frisco-Dallas

Hyatt Regency Frisco-Dallas

Hyatt Regency Frisco-Dallas
4.0 star property
6.3 km from Medical City Frisco
9.4 out of 10, Exceptional, (1004)
"Nice place with comfortable beds "
United States
John
The price is 4.583.995 ₫
5.328.995 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hyatt Regency Frisco-Dallas
Exterior
Holiday Inn Express Frisco Legacy Park Area by IHG

Holiday Inn Express Frisco Legacy Park Area by IHG

Holiday Inn Express Frisco Legacy Park Area by IHG
2.5 star property
5.2 km from Medical City Frisco
6.6 out of 10, (1008)
"Good breakfast, nice room, clean."
United States
Jorge
The price is 2.104.560 ₫
2.425.716 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Frisco Legacy Park Area by IHG
Terrace/patio
Home2 Suites by Hilton Dallas-Frisco

Home2 Suites by Hilton Dallas-Frisco

Home2 Suites by Hilton Dallas-Frisco
3.0 star property
6.5 km from Medical City Frisco
9.4 out of 10, Exceptional, (1003)
"Great stay, very convenient location."
United States
Nancy
The price is 2.782.754 ₫
3.207.402 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Home2 Suites by Hilton Dallas-Frisco
In-room safe, desk, laptop workspace, iron/ironing board
Hyatt House Dallas/Frisco

Hyatt House Dallas/Frisco

Hyatt House Dallas/Frisco
3.5 star property
5.8 km from Medical City Frisco
8.8 out of 10, Excellent, (1005)
"Everything was great!"
United States
Dr. Cryslynn
The price is 2.609.654 ₫
3.086.312 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hyatt House Dallas/Frisco
Exterior
Aloft Frisco

Aloft Frisco

Aloft Frisco
3.0 star property
5.5 km from Medical City Frisco
8.6 out of 10, Excellent, (1003)
"Great place to stay while in the metroplex! Definitely coming back!! "
United States
Olivia
The price is 2.213.734 ₫
2.551.549 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Aloft Frisco
13 restaurants, breakfast, lunch, dinner served; seafood
Omni PGA Frisco Resort & Spa

Omni PGA Frisco Resort & Spa

Omni PGA Frisco Resort & Spa
5.0 star property
7 km from Medical City Frisco
9.6 out of 10, Exceptional, (380)
"Loved everything about our stay!"
United States
Sarah
The price is 7.426.992 ₫
10.053.037 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni PGA Frisco Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Medical City Frisco Hotel Reviews

1/2 Mi to Frisco Commons! Poolside 4-season Oasis

1/2 Mi to Frisco Commons! Poolside 4-season Oasis

10/10 Excellent
"Great host, comfortable home for our needs. "
Craig 3-night trip
Posted 10 months ago
1/2 Mi to Frisco Commons! Poolside 4-season Oasis

Hotels near other Medical City Frisco attractions

Toyota Stadium

4.5/5 (268 reviews)
Catch an event at Toyota Stadium during your trip to Frisco. Experience the area's entertainment choices or attend a sporting event.
See properties

Cinemark Frisco Square

You can take time to visit Cinemark Frisco Square during your travels to Frisco. Attend a sporting event or visit the shops in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Medical City Frisco?
Medical City Frisco is located in Frisco. This family-friendly area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.
How many hotels are there close to Medical City Frisco?
Expedia has 40 hotels and other accommodation options within a mile from Medical City Frisco.
If I need to cancel the hotel reservation for my stay near Medical City Frisco, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to view the best deals near Medical City Frisco.
What can I see and do near Medical City Frisco?
You'll want to browse the exhibits at National Videogame Museum and Museum of the American Railroad. Main Event, Frisco Soccer Complex and KidZania USA are some favourites close by Medical City Frisco. A shopping trip to Stonebriar Centre Mall, Legacy West or The Star District might be the perfect place to find that souvenir you've been looking for.

Explore a world of travel with Expedia