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Our top choices for Mesilla business-friendly hotels

Deluxe Room, 2 Double Beds, Non Smoking, Mountain View | Premium bedding, desk, iron/ironing board, free cots/infant beds
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very good, (2291)
"Clean, helpful, easy parking"
United States
Alan
The price is 1.491.607 ₫
1.757.101 ₫ total
includes taxes & fees
21 Dec - 22 Dec
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Restaurant
Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1005)
"Great size rooms great location. Breakfast was average breakfast not bad"
United States
Juan Antonio
The price is 2.378.153 ₫
2.762.498 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn & Suites Las Cruces I-10
Lobby
Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very good, (1004)
"Dated but a very nice and clean place to stay. "
United States
Lynn
The price is 1.834.913 ₫
2.140.337 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Ramada Hotel & Conference Center by Wyndham Las Cruces
Exterior
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very good, (1292)
"Friendly staff and spacious King room."
United States
Donald
The price is 1.274.574 ₫
1.511.007 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Las Cruces
Free daily buffet breakfast
Best Western Mission Inn

Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1238)
"Very comfortable place to stay"
United States
Maryann
The price is 2.012.749 ₫
2.348.025 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Best Western Mission Inn
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1600)
"We had a wonderful stay. "
United States
Amber
The price is 2.660.868 ₫
3.795.846 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hotel Encanto de Las Cruces
Interior
Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1004)
"Great stay"
United States
Myles
The price is 2.146.651 ₫
2.499.856 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton Garden Inn Las Cruces
Lobby
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1006)
"Clean room, good breakfast, nice staff, and great pricing. "
United States
Shahzad
The price is 2.472.595 ₫
2.869.568 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Las Cruces
Indoor pool
Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1003)
"Nice place"
United States
chris
The price is 2.587.820 ₫
3.000.097 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Comfort Inn & Suites Las Cruces Mesilla
Desk, laptop workspace, blackout curtains, soundproofing
Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (1002)
"Was a place to rest my head during my travels for a night so affordable & room was in good condition. "
United States
Gloria
The price is 1.210.121 ₫
1.437.925 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Super 8 by Wyndham Las Cruces/White Sands Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesilla Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in Mesilla cost?
Expect to pay between 1.437.925 ₫ and 3.795.846 ₫ per night for business-friendly hotels in Mesilla. Awesome deals on stays that cater to work-related travellers as just a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Mesilla?
There are multiple business-friendly hotels in Mesilla that have a total average guest review rating of 8.5. Comfort Suites Las Cruces I-25 North is a hit with lots of corporate travellers. This 2.5-stars property features amenities such as an electric car charging station and pillow top mattresses. Courtyard by Marriott Las Cruces at NMSU is another highly rated option. It has a 3-stars rating and conveniences including a cafe and a swimming pool.
How many business-friendly hotels are there in Mesilla?
Choose from 1 business-friendly hotels in Mesilla. Whether you're looking for amenities like coworking spaces, dependable WiFi or meeting rooms, Expedia is here to help you find the ideal place to get the job done.
What are the best cheap business-friendly hotels in Mesilla?
Business-friendly hotels in Mesilla start at 1.437.925 ₫ per night, so your next official work trip doesn't need to cost a fortune. Comfort Suites Las Cruces I-25 North is a cost-effective choice that offers many amenities, like pillow top mattresses and a swimming pool. Holiday Inn Express & Suites Las Cruces North, an IHG Hotel is another budget stay that's popular with corporate guests. Conveniences here include pillow top mattresses and a swimming pool. Don't forget to add some sightseeing to your Mesilla work trip. Find time to explore some fun and free attractions, such as Mesilla Valley Bosque State Park and Las Cruces Museum of Fine Arts and Culture. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Mesilla that are also business friendly?
Holidaying with the fam, and staying in touch with colleagues, is a breeze at Comfort Suites Las Cruces I-25 North. Take advantage of amenities like complimentary breakfast and a laundry service at this leading 2.5-stars stay in Mesilla. Also look into Drury Inn & Suites Las Cruces. Get your meetings out of the way and then enjoy quality time with your loved ones at this 3-stars pick. Complimentary breakfast and a picnic area are just the start of its many conveniences. Once work is out of the way, there's no shortage of family-friendly attractions to visit around Mesilla. Museum of Nature & Science and New Mexico Farm and Ranch Heritage Museum promise fun for young and old.
Why book your business-friendly hotel in Mesilla with Expedia?
With top amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly hotels come with all you'll need to close your big work deal — and then unwind! Enter your travel destination and preferred dates and Expedia will help you organise the rest.
How can I find cheap business-friendly hotels in Mesilla?
When you're travelling for work in Mesilla, our "business friendly" filter will help you find the right hotel. From included breakfast and free WiFi to meeting rooms and work desks, they come with the amenities you need for a comfortable and productive stay. Another tip? Refine your search by your preferred star rating and budget to view the most affordable accommodation.
What is there to do in Mesilla near my business-friendly hotel?
There are plenty of impressive things to put on your itinerary in Mesilla. Discover popular attractions like Las Cruces Museum of Art, Rio Grande Vineyards and Winery and Mesilla Valley Bosque State Park. Las Cruces Museum of Fine Arts and Culture, Las Cruces Community Theatre and Museum of Nature & Science are other must-see's.