Top hotels in Mesopotamia

Marriott Corrientes Hotel
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
4.189.431 ₫
4.189.431 ₫ total
4 Sept - 5 Sept
9.8/10 Exceptional! (43 reviews)
"Impecable, 10/10"
Reviewed on 16 Aug 2026

O2 Hotel Gualeguaychú
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
963.843 ₫
963.843 ₫ total
31 Aug - 1 Sept

Hathor Concordia
Ruta Nacional 14-km 264.5 Concordia Entre Rios
Fully refundableReserve now, pay when you stay
1.259.046 ₫
1.545.904 ₫ total
31 Aug - 1 Sept
8.8/10 Excellent! (389 reviews)
"AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road."
Reviewed on 22 Dec 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Mesopotamia attractions

Basilica Nuestra Senora De Itati
Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.

El Palmar National Park
8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

Costanera de Corrientes
9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
Termas de Federacion
10.0/10 (2 reviews)
Bring the children to Termas de Federacion and enjoy this exciting theme park in Federacion. Stroll along the beaches or discover the area's waterfalls.
Victoria Beach
If a restful holiday is part of your travel plans, Victoria Beach might be the perfect place to visit during your trip to Victoria. Make some time to visit the monuments while you're in the area.
Concepción del Uruguay City Racetrack
You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
Termas Concepcion Entrerios
Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this theme park in Concepción del Uruguay. Experience the area's art scene and museums.
Portal Carambola
You can take time to visit Portal Carambola during your travels to Concepción. While you're in the area, wander around the parks.
Frequently asked questions
How much does a Mesopotamia holiday package cost?
Maybe less than you might think — from only , actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia holiday package with Expedia is a great way to save. We offer more than 550 partner airlines and 1null000null000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travellers.
How far in advance should I book my Mesopotamia holiday?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travellers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including holiday rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia holiday package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia holiday package?
Don't worry if you're rethinking your Mesopotamia holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realise life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.

