Mesopotamia Holidays

Book a Hotel + Flight or Car together to unlock savings

Top hotels in Mesopotamia

Arena Resort
Arena Resort
Avenida Las Violetas 500, Federacion, Entre Rios
"nos resulto todo de maravilla! el desayuno completo. Hubo dificultad con el WiFi en la habitacion no me pude conectar. el SPA estupendo"

Reviewed on 23 Nov 2016

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Arena Resort
Hathor Concordia
Hathor Concordia
3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (342 reviews)
"Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful."

Reviewed on 31 Dec 2024

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Hathor Concordia
O2 Hotel Gualeguaychú
O2 Hotel Gualeguaychú
2.5 out of 5
115 3 de Febrero, Gualeguaychú, Entre Ríos
Fully refundableReserve now, pay when you stay
The price is 992.978 ₫ per night from 29 Jun to 30 Jun
992.978 ₫
992.978 ₫ total
29 Jun - 30 Jun
7.4/10 Good! (58 reviews)
"Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice."

Reviewed on 2 Jan 2025

O2 Hotel Gualeguaychú
See all 455 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mesopotamia holiday package cost?
Maybe less than you might think --- from only , actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia holiday package with Expedia is a great way to save. We offer more than 550 partner airlines and 1null000null000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travellers.
How far in advance should I book my Mesopotamia holiday?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travellers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including holiday rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia holiday package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia holiday package?
Don't worry if you're rethinking your Mesopotamia holiday package --- you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realise life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.

Popular places to visit

Termas de Federacion

Bring the children to Termas de Federacion and enjoy this exciting theme park in Federacion. Stroll along the beaches or discover the area's waterfalls.

Termas de Federacion

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.

Basilica Nuestra Senora De Itati

Termas Concepcion Entrerios

Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this theme park in Concepción del Uruguay. Experience the area's art scene and museums.

Termas Concepcion Entrerios