The Best Hotels in Middletown, San Diego - 2026 Updated Prices

A marina with yachts and a city skyline with tall buildings.

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Our top choices for Middletown hotels

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

Middletown

omokayode

4.160.767 ₫ total

includes taxes & fees

8 Sept - 9 Sept

A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.

2. Best Western Seven Seas

2.5 km from Middletown

Colleen

2.535.429 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A modern lobby with a stone wall, blue sofas, a reception desk, and a staircase.

3. Kings Inn San Diego

2.1 km from Middletown

Manuel

2.683.816 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A resort with a large swimming pool surrounded by lounge chairs and palm trees.

4. Handlery Hotel

2.3 km from Middletown

Ronald

3.572.378 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A rectangular swimming pool with lounge chairs and umbrellas, surrounded by tall trees and greenery.

5. Days Inn by Wyndham San Diego Hotel Circle

2.4 km from Middletown

Alyssa

2.670.592 ₫ total

includes taxes & fees

9 Sept - 10 Sept

A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.

6. Legacy Resort Hotel & Spa

2.1 km from Middletown

amy

5.214.018 ₫ total

includes taxes & fees

13 Sept - 14 Sept

A balcony with wicker furniture overlooking a marina and a coastal cityscape.

7. Sheraton San Diego Resort

2.5 km from Middletown

Pooja

5.874.152 ₫ total

includes taxes & fees

8 Sept - 9 Sept

A spacious lobby with a large seating area, a wooden ceiling, and large windows offering a view of the outdoor patio area.

8. Hampton Inn & Suites San Diego Airport Liberty Station

3.6 km from Middletown

David

5.606.329 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A modern dining area with multiple tables and chairs, large windows, and artwork on the walls.

9. Comfort Inn San Diego Old Town

Old Town San Diego, 2.1 km from Middletown

Heather

3.541.045 ₫ total

includes taxes & fees

28 Sept - 29 Sept

A hotel sign with palm trees in the background.

10. The Atwood Hotel San Diego - SeaWorld/Zoo

2.2 km from Middletown

jannet

2.831.228 ₫ total

includes taxes & fees

16 Sept - 17 Sept

An outdoor patio area with tables and chairs, string lights, and a building with balconies.

11. Fairfield Inn & Suites San Diego Old Town

Old Town San Diego, 2 km from Middletown

Anthony

3.795.797 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A hotel breakfast area with a long counter displaying various food items, including fruits, pastries, and a coffee station.

12. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.7 km from Middletown

Philomena

3.957.467 ₫ total

includes taxes & fees

1 Oct - 2 Oct

A hotel courtyard with outdoor seating, palm trees, and a view of the ocean at dusk.

13. Wyndham San Diego Bayside

2.3 km from Middletown

Jennifer

5.506.885 ₫ total

includes taxes & fees

20 Sept - 21 Sept

14. Hard Rock Hotel San Diego

Gaslamp Quarter, 3.8 km from Middletown

Carlos

6.428.806 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A hotel entrance with a covered outdoor area, palm trees, and a white building with multiple windows and balconies.

15. Courtyard by Marriott Old Town

Old Town San Diego, 2.2 km from Middletown

Christine

4.560.052 ₫ total

includes taxes & fees

7 Sept - 8 Sept

An outdoor lounge area with seating, a fire feature, and a pool in the background.

16. Town and Country San Diego

2.7 km from Middletown

Sol

6.271.831 ₫ total

includes taxes & fees

6 Sept - 7 Sept

A hotel room with a large window offering a city view, a bed, a chair, and a small table.

17. The DEXTRO Little Italy, BW Premier Collection

2.2 km from Middletown

Patricia

4.214.341 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A building with a "Bienvenidos" sign, palm trees, and a well-maintained garden.

18. Old Town Inn

2.7 km from Middletown

Layne

4.464.741 ₫ total

includes taxes & fees

7 Sept - 8 Sept

A modern building with multiple windows, outdoor seating, and a chessboard.

19. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

3.3 km from Middletown

Joshua

3.907.588 ₫ total

includes taxes & fees

9 Sept - 10 Sept

A hotel room with a large bed, a desk, a chair, a painting, and a view of the city.

20. Best Western Plus Marina Gateway Hotel

10.8 km from Middletown

Samuel

4.281.090 ₫ total

includes taxes & fees

7 Sept - 8 Sept

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Where to stay in Middletown

Find the best Middletown areas for the activities you enjoy most.

A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

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A beach with surfers and swimmers during sunset.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

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A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

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Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

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An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

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Top Middletown Hotel Reviews

Best Western Seven Seas

10/10 Excellent

"Comfortable"

Manchester Grand Hyatt San Diego

8/10 Good

"Room was excellent, very comfortable and stylish. Ordering for room delivery a little complicated; QR code on menu linked to multiple webpages that were not intuitive nor included breakfast ordering options- tried ordering at dinner too and webpage would not allow order to be placed- ended up calling in order both times. Dismayed main pool area was completely under construction in August, and they started at 8am, so no sleeping in. Other than that, very pleasant stay"

Frequently asked questions

What's it like in Middletown?

Middletown is a neighbourhood that travellers like for its live music, bars and theatres. Consider a visit to The Casbah San Diego as part of your Middletown travel plans.

How many hotels can I expect to find in the Middletown area?

Expedia has 75 hotels and other accommodation options in Middletown to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Middletown, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view top deals in Middletown.

What are the top things to see and do in Middletown?

The Casbah San Diego is an attraction you might want to check out while you're in Middletown. When you're sightseeing in San Diego, San Diego Zoo and Petco Park are also worth a stop.

How can I get around Middletown and the greater San Diego area?

Ready to get out and explore the city? Middletown Station is the closest metro station.

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Our top choices for Middletown hotels

1. City24 Hotel Little Italy Mission Hills

2. Best Western Seven Seas

3. Kings Inn San Diego

4. Handlery Hotel

5. Days Inn by Wyndham San Diego Hotel Circle

6. Legacy Resort Hotel & Spa

7. Sheraton San Diego Resort

8. Hampton Inn & Suites San Diego Airport Liberty Station

9. Comfort Inn San Diego Old Town

10. The Atwood Hotel San Diego - SeaWorld/Zoo

11. Fairfield Inn & Suites San Diego Old Town

12. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

13. Wyndham San Diego Bayside

14. Hard Rock Hotel San Diego

15. Courtyard by Marriott Old Town

16. Town and Country San Diego

17. The DEXTRO Little Italy, BW Premier Collection

18. Old Town Inn

19. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

20. Best Western Plus Marina Gateway Hotel

Where to stay in Middletown

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Mission Bay

Top Middletown Hotel Reviews

Best Western Seven Seas

Frequently asked questions

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